MIR199A1 (microRNA 199a-1)

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Gene Gene ontology Other IDs Pathways Diseases linked via similar genes

Gene

• Entrez ID: 406976
• Gene name: MicroRNA 199a-1
• Gene symbol: MIR199A1
• Synonyms (NCBI Gene): MIR-199-s, MIRN199A1, mir-199a-1
• Chromosome: 19
• Chromosome location: 19p13.2
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO) Show/Hide all (47)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000320	Process	Re-entry into mitotic cell cycle	ISS
GO:0002091	Process	Negative regulation of receptor internalization	IDA	26163491
GO:0003730	Function	MRNA 3'-UTR binding	IDA	23764775, 24299514
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0007204	Process	Positive regulation of cytosolic calcium ion concentration	IMP	27038547
GO:0010507	Process	Negative regulation of autophagy	ISS
GO:0010595	Process	Positive regulation of endothelial cell migration	IMP	23142051
GO:0010629	Process	Negative regulation of gene expression	IDA	23764775
GO:0010667	Process	Negative regulation of cardiac muscle cell apoptotic process	ISS
GO:0010989	Process	Negative regulation of low-density lipoprotein particle clearance	IDA	26163491
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	22821565
GO:0030514	Process	Negative regulation of BMP signaling pathway	IDA	22821565
GO:0032008	Process	Positive regulation of TOR signaling	ISS
GO:0032686	Process	Negative regulation of hepatocyte growth factor production	IMP	28358369
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	22821565, 23764775, 24011070, 24299514, 25706326, 26160071, 26163491, 27038547, 28358369
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	23142051
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	24299514
GO:0045019	Process	Negative regulation of nitric oxide biosynthetic process	IMP	27038547
GO:0045663	Process	Positive regulation of myoblast differentiation	IMP	23764775
GO:0045765	Process	Regulation of angiogenesis	ISS
GO:0045766	Process	Positive regulation of angiogenesis	IMP	23142051
GO:0050728	Process	Negative regulation of inflammatory response	IMP	24299514
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ISS
GO:0060043	Process	Regulation of cardiac muscle cell proliferation	ISS
GO:0060044	Process	Negative regulation of cardiac muscle cell proliferation	ISS
GO:0060045	Process	Positive regulation of cardiac muscle cell proliferation	ISS
GO:0060392	Process	Negative regulation of SMAD protein signal transduction	IDA	22821565
GO:0061049	Process	Cell growth involved in cardiac muscle cell development	ISS
GO:0061051	Process	Positive regulation of cell growth involved in cardiac muscle cell development	ISS
GO:0061052	Process	Negative regulation of cell growth involved in cardiac muscle cell development	ISS
GO:0061766	Process	Positive regulation of lung blood pressure	ISS
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IMP	28358369
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IDA	23764775
GO:1900102	Process	Negative regulation of endoplasmic reticulum unfolded protein response	IDA	24299514
GO:1900747	Process	Negative regulation of vascular endothelial growth factor signaling pathway	IMP	28358369
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	22821565, 23764775, 24011070, 24299514, 25706326, 26160071, 26163491, 28358369
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	23142051
GO:1903244	Process	Positive regulation of cardiac muscle hypertrophy in response to stress	ISS
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	IMP	28358369
GO:1904465	Process	Negative regulation of matrix metallopeptidase secretion	IMP	28358369
GO:1905180	Process	Positive regulation of cardiac muscle tissue regeneration	ISS
GO:1905203	Process	Regulation of connective tissue replacement	ISS
GO:1905205	Process	Positive regulation of connective tissue replacement	ISS
GO:2000288	Process	Positive regulation of myoblast proliferation	IMP	23764775
GO:2001237	Process	Negative regulation of extrinsic apoptotic signaling pathway	IDA	22821565

Other IDs

• MIM: 610719
• HGNC: 31571
• e!Ensembl: ENSG00000207752

Interactions View interactions

Pathways

KEGG Pathway:

MicroRNAs in cancer

Related Genes

No strongly related genes found yet for MIR199A1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MIR199A1.