MIR181B1 (microRNA 181b-1) | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	406955
Gene name	MicroRNA 181b-1
Gene symbol	MIR181B1
Synonyms (NCBI Gene)	MIRN181B1mir-181b-1
Chromosome	1
Chromosome location	1q32.1
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	18184693
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0009968	Process	Negative regulation of signal transduction	IGI	25505240
GO:0010917	Process	Negative regulation of mitochondrial membrane potential	ISS
GO:0030335	Process	Positive regulation of cell migration	IMP	23993976
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18184693, 18728182, 25505240, 27756793, 28323882
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	23993976, 27756793
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IMP	23993976, 25762865
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	25535255
GO:0045429	Process	Positive regulation of nitric oxide biosynthetic process	IGI	22232059
GO:0045603	Process	Positive regulation of endothelial cell differentiation	IGI	22232059
GO:0045766	Process	Positive regulation of angiogenesis	IGI	22232059
GO:0045824	Process	Negative regulation of innate immune response	IGI	25505240
GO:0050728	Process	Negative regulation of inflammatory response	ISS
GO:0050729	Process	Positive regulation of inflammatory response	IGI	25505240
GO:0050765	Process	Negative regulation of phagocytosis	IGI	25505240
GO:0061889	Process	Negative regulation of astrocyte activation	ISS
GO:0071356	Process	Cellular response to tumor necrosis factor	ISS
GO:0110015	Process	Positive regulation of elastin catabolic process	ISS
GO:0120041	Process	Positive regulation of macrophage proliferation	ISS
GO:1900425	Process	Negative regulation of defense response to bacterium	IGI	25505240
GO:1900745	Process	Positive regulation of p38MAPK cascade	IMP	23993976
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18184693, 18728182, 25505240, 25535255, 28323882
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	23993976, 25762865
GO:2000271	Process	Positive regulation of fibroblast apoptotic process	ISS

MIM	HGNC	e!Ensembl
612744	31550	ENSG00000207975

Interactions View interactions

KEGG Pathway
MicroRNAs in cancer