MIR181A2 (microRNA 181a-2) | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	406954
Gene name	MicroRNA 181a-2
Gene symbol	MIR181A2
Synonyms (NCBI Gene)	MIRN181AMIRN181A2hsa-mir-181a-2mir-181a-2
Chromosome	9
Chromosome location	9q33.3
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	22492871, 24848932, 27767084
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0005615	Component	Extracellular space	IDA	26322847
GO:0010629	Process	Negative regulation of gene expression	IGI	18728182
GO:0016442	Component	RISC complex	IEA
GO:0030335	Process	Positive regulation of cell migration	IMP	23993976
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IMP	22714950
GO:0032690	Process	Negative regulation of interleukin-1 alpha production	IDA	23516523
GO:0032691	Process	Negative regulation of interleukin-1 beta production	IDA	23516523
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	23516523
GO:0032717	Process	Negative regulation of interleukin-8 production	IDA	24848932
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IDA	23516523
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18728182, 22042811, 22492871, 24098322, 24848932, 27767084, 28323882
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	23993976
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IMP	23993976
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	25535255
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IMP	22714950
GO:0045177	Component	Apical part of cell	IDA	26322847
GO:0045429	Process	Positive regulation of nitric oxide biosynthetic process	IGI	22232059
GO:0045598	Process	Regulation of fat cell differentiation	ISS
GO:0045603	Process	Positive regulation of endothelial cell differentiation	IGI	22232059
GO:0050728	Process	Negative regulation of inflammatory response	IDA	23516523
GO:1900745	Process	Positive regulation of p38MAPK cascade	IMP	23993976
GO:1902461	Process	Negative regulation of mesenchymal stem cell proliferation	IMP	22714950
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18728182, 22042811, 22492871, 24848932, 25535255, 27767084, 28323882
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	22714950, 23993976
GO:1903427	Process	Negative regulation of reactive oxygen species biosynthetic process	IDA	23516523

MIM	HGNC	e!Ensembl
612743	31549	ENSG00000207595

Interactions View interactions

KEGG Pathway
MicroRNAs in cancer