MIR15B (microRNA 15b)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene Gene ontology Other IDs Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 406949
• Gene name: MicroRNA 15b
• Gene symbol: MIR15B
• Synonyms (NCBI Gene): MIRN15B, hsa-mir-15b, miR-15b
• Chromosome: 3
• Chromosome location: 3q25.33
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO) Show/Hide all (39)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001569	Process	Branching involved in blood vessel morphogenesis	IMP	23688497
GO:0003300	Process	Cardiac muscle hypertrophy	ISS
GO:0003730	Function	MRNA 3'-UTR binding	IDA	23688497, 26179126, 26440600, 29961672
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0005615	Component	Extracellular space	IDA	28254819
GO:0008285	Process	Negative regulation of cell population proliferation	IGI	22139073
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IDA	27208409
GO:0016525	Process	Negative regulation of angiogenesis	ISS
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	ISS
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	HDA	18320040
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18449891, 21454377, 23487264, 23688497, 25261849, 25594541, 26440600, 27208409, 28254819, 29207665, 29961672
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	26179126
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IGI	25403480
GO:0043065	Process	Positive regulation of apoptotic process	IDA	25261849
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	23487264
GO:0043524	Process	Negative regulation of neuron apoptotic process	IGI	29207665
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IDA	28254819
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IMP	23688497
GO:0045719	Process	Negative regulation of glycogen biosynthetic process	IMP	26179126
GO:0045727	Process	Positive regulation of translation	IGI	25403480
GO:0045930	Process	Negative regulation of mitotic cell cycle	ISS
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	IMP	26179126
GO:0050728	Process	Negative regulation of inflammatory response	IGI	29961672
GO:0061045	Process	Negative regulation of wound healing	IMP	23688497
GO:1900077	Process	Negative regulation of cellular response to insulin stimulus	IMP	26179126
GO:1901164	Process	Negative regulation of trophoblast cell migration	IDA	27208409
GO:1901223	Process	Negative regulation of non-canonical NF-kappaB signal transduction	IGI	29961672
GO:1902430	Process	Negative regulation of amyloid-beta formation	IDA	29961672
GO:1902992	Process	Negative regulation of amyloid precursor protein catabolic process	IDA	29961672
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18449891, 23688497, 25261849, 25594541, 26179126, 28254819, 29207665, 29961672
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	27208409
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	HMP	18320040
GO:1905064	Process	Negative regulation of vascular associated smooth muscle cell differentiation	IMP	18548003
GO:1905205	Process	Positive regulation of connective tissue replacement	ISS
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IDA	28254819
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IDA	25261849

Other IDs

• MIM: 619572
• HGNC: 31544
• e!Ensembl: ENSG00000207779

Interactions View interactions

Pathways

KEGG Pathway:

MicroRNAs in cancer

Related Genes

No strongly related genes found yet for MIR15B.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MIR15B.