MIR149 (microRNA 149) | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	406941
Gene name	MicroRNA 149
Gene symbol	MIR149
Synonyms (NCBI Gene)	MIRN149mir-149
Chromosome	2
Chromosome location	2q37.3
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

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GO ID	Ontology	Definition	Evidence	Reference
GO:0008285	Process	Negative regulation of cell population proliferation	IMP	33102210
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IDA	25916550
GO:0016442	Component	RISC complex	IEA
GO:0030336	Process	Negative regulation of cell migration	IDA	26498692
GO:0032715	Process	Negative regulation of interleukin-6 production	IGI	24299952
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IGI	23595570
GO:0032916	Process	Positive regulation of transforming growth factor beta3 production	ISS
GO:0032967	Process	Positive regulation of collagen biosynthetic process	ISS
GO:0034144	Process	Negative regulation of toll-like receptor 4 signaling pathway	IMP	28260877
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	24463821, 25916550, 26498692, 29029439, 29331391, 33102210
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IGI	23595570, 24299952
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	28260877
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IMP	24463821
GO:0044344	Process	Cellular response to fibroblast growth factor stimulus	IMP	24463821
GO:0050728	Process	Negative regulation of inflammatory response	ISS
GO:0051497	Process	Negative regulation of stress fiber assembly	IDA	26498692
GO:0071354	Process	Cellular response to interleukin-6	IDA	29029439
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IMP	24463821
GO:1901223	Process	Negative regulation of non-canonical NF-kappaB signal transduction	ISS
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	24463821, 25916550, 26498692, 28260877, 29331391, 33102210
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IGI	23595570
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IMP	24463821
GO:1904893	Process	Negative regulation of receptor signaling pathway via STAT	IDA	29029439
GO:2000545	Process	Negative regulation of endothelial cell chemotaxis to fibroblast growth factor	IMP	24463821

MIM	HGNC	e!Ensembl
615209	31536	ENSG00000207611

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