MIR140 (microRNA 140)

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Gene Gene information from NCBI Gene database.
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Entrez ID 406932
Gene name MicroRNA 140
Gene symbol MIR140
Synonyms (NCBI Gene)
MIRN140SEDNmiRNA140mir-140
Chromosome 16
Chromosome location 16q22.1
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0003730 Function MRNA 3'-UTR binding IDA 24530397, 24928442, 30233718
GO:0005615 Component Extracellular space HDA 26646931
GO:0010628 Process Positive regulation of gene expression IDA 24530397
GO:0010628 Process Positive regulation of gene expression IDA 27021683
GO:0010629 Process Negative regulation of gene expression IDA 30233718
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
611894 31527 ENSG00000208017
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession Evidence Score
Spondyloepiphyseal dysplasia MIR140 type Nishimura Pathogenic rs1567443039 RCV000735792
★★★★★
★★★★☆
ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Spondyloepiphyseal dysplasia, nishimura type Pathogenic rs1567443039 RCV000853066
★★★★★
★★★★☆
ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Associations from Text Mining Disease associations identified through text mining
Show/Hide Text Mining Associations (163)
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute Kidney Insufficiency Acute Kidney Insufficiency CTD_human_DG 30682439
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of lung (disorder) Lung adenocarcinoma BEFREE 28005074, 31043858
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenoid Cystic Carcinoma Adenocarcinoma BEFREE 31762692
★★★★★
★☆☆☆☆
Found in Text Mining only
Alveolitis, Fibrosing Alveolitis CTD_human_DG 25926378
★★★★★
★☆☆☆☆
Found in Text Mining only
Alzheimer Disease Alzheimer disease Pubtator 32846274 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Angina, Unstable Intermediate coronary syndrome BEFREE 28961259
★★★★★
★☆☆☆☆
Found in Text Mining only
Arteriosclerosis Arteriosclerosis BEFREE 30483753
★★★★★
★☆☆☆☆
Found in Text Mining only
Arthritis Arthritis BEFREE 26473405
★★★★★
★☆☆☆☆
Found in Text Mining only
Arthritis Arthritis Pubtator 27165343 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Arthritis Rheumatoid Rheumatoid arthritis Pubtator 38241560 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only

No strongly related genes found yet for MIR140.

No additional diseases found yet through genes similar to MIR140.