MIR138-1 (microRNA 138-1) | Gene Details, Disease Associations & Pathways | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	406929
Gene name	MicroRNA 138-1
Gene symbol	MIR138-1
Synonyms (NCBI Gene)	MIRN138-1mir-138-1
Chromosome	3
Chromosome location	3p21.32
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	21444814
GO:0005737	Component	Cytoplasm	IDA	25336585
GO:0007162	Process	Negative regulation of cell adhesion	ISS
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	21079996, 24171926
GO:0010888	Process	Negative regulation of lipid storage	IDA	31769250
GO:0016442	Component	RISC complex	IEA
GO:0030336	Process	Negative regulation of cell migration	IDA	20232393, 24171926
GO:0033689	Process	Negative regulation of osteoblast proliferation	ISS
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	20232393, 21079996, 23319823, 24171926, 24244340, 26891291, 28537665, 31769250
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	20232393, 21444814
GO:0042311	Process	Vasodilation	IMP	24244340
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	23319823
GO:0044854	Process	Plasma membrane raft assembly	IDA	23319823
GO:0045599	Process	Negative regulation of fat cell differentiation	IDA	31769250
GO:0045668	Process	Negative regulation of osteoblast differentiation	IMP	21444814
GO:0045668	Process	Negative regulation of osteoblast differentiation	ISS
GO:0050728	Process	Negative regulation of inflammatory response	IDA	28537665
GO:0051497	Process	Negative regulation of stress fiber assembly	IDA	20232393
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ISS
GO:0060761	Process	Negative regulation of response to cytokine stimulus	IDA	28537665
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IMP	21444814
GO:1900045	Process	Negative regulation of protein K63-linked ubiquitination	IMP	23319823
GO:1902532	Process	Negative regulation of intracellular signal transduction	IDA	21444814
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	20232393, 21079996, 21444814, 23319823, 24171926, 24244340, 26891291, 28537665, 31769250
GO:1903671	Process	Negative regulation of sprouting angiogenesis	IDA	24244340
GO:1904178	Process	Negative regulation of adipose tissue development	IDA	31769250
GO:1905460	Process	Negative regulation of vascular associated smooth muscle cell apoptotic process	ISS

MIM	HGNC	e!Ensembl
613394	31524	ENSG00000207954

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