METTL2A (methyltransferase 2A, tRNA N3-cytidine)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 339175 |
| Gene name | Methyltransferase 2A, tRNA N3-cytidine |
| Gene symbol | METTL2A |
| Synonyms (NCBI Gene) |
METTL2
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| Chromosome | 17 |
| Chromosome location | 17q23.2 |
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miRNA
miRNA information provided by mirtarbase database.
424
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96IZ6 | ||||||||||
| Protein name | tRNA N(3)-cytidine methyltransferase METTL2A (EC 2.1.1.-) (Methyltransferase-like protein 2A) | ||||||||||
| Protein function | S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU) (PubMed:28655767, PubMed:34268557). N(3)-methylcytidine methylation | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MAGSYPEGAPAVLADKRQQFGSRFLRDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQ |
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| Sequence length | 378 | ||||||||||
| Interactions | View interactions | ||||||||||
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Related Genes
Genes most often co-reported with METTL2A across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to METTL2A (see Related Genes above), that are NOT already directly curated for METTL2A itself -- a lead worth checking, not a confirmed association.
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