MEIOC (meiosis specific with coiled-coil domain)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 284071
• Gene name: Meiosis specific with coiled-coil domain
• Gene symbol: MEIOC
• Synonyms (NCBI Gene): C17orf104
• Chromosome: 17
• Chromosome location: 17q21.31

miRNA Show/Hide all (10)

miRTarBase ID	miRNA	Experiments	Reference
MIRT643935	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT643934	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT643933	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT643932	hsa-miR-5009-3p	HITS-CLIP	23824327
MIRT643931	hsa-miR-3130-3p	HITS-CLIP	23824327
MIRT643930	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT643929	hsa-miR-4252	HITS-CLIP	23824327
MIRT643928	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT643927	hsa-miR-3685	HITS-CLIP	23824327
MIRT643926	hsa-miR-384	HITS-CLIP	23824327

Gene ontology (GO) Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0006302	Process	Double-strand break repair	IEA
GO:0007130	Process	Synaptonemal complex assembly	IEA
GO:0007141	Process	Male meiosis I	IBA
GO:0007141	Process	Male meiosis I	IEA
GO:0007144	Process	Female meiosis I	IBA
GO:0007144	Process	Female meiosis I	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0007286	Process	Spermatid development	IEA
GO:0007286	Process	Spermatid development	ISS
GO:0048255	Process	MRNA stabilization	IBA
GO:0048255	Process	MRNA stabilization	IEA
GO:0048599	Process	Oocyte development	IEA
GO:0048599	Process	Oocyte development	ISS
GO:0051310	Process	Metaphase chromosome alignment	IEA
GO:0051321	Process	Meiotic cell cycle	IEA
GO:0051729	Process	Germline cell cycle switching, mitotic to meiotic cell cycle	IEA
GO:0051729	Process	Germline cell cycle switching, mitotic to meiotic cell cycle	ISS
GO:0070192	Process	Chromosome organization involved in meiotic cell cycle	IEA
GO:0070192	Process	Chromosome organization involved in meiotic cell cycle	ISS

Other IDs

• MIM: 616934
• HGNC: 26670
• e!Ensembl: ENSG00000180336

Protein

• UniProt ID: A2RUB1
• Protein name: Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein)
• Protein function: Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent o
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15189	MEIOC	747 → 912	Meiosis-specific coiled-coil domain-containing protein MEIOC	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in fetal ovaries (PubMed:26742488). Expressed in testis (PubMed:28380054). {ECO:0000269|PubMed:26742488, ECO:0000269|PubMed:28380054}.
• Sequence:

  MEVRRGDTCPRPHPSGLREEGLEPKVAFPGGANRCWNLGADAGSRLTDVFGSVMLTGSAS
  FYDCYTSQSEDNVDLRQTYTPFSSTEYSSSVDSSLFCAPWSTYGDDIKQPSNSQISIKNR
  IQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFADHHDLLT
  ETKRPIDTVISQQAFYSDESVSAMEKQYLRNSNLTPQQKIDELHHGFTGLDLEEQWMYPS
  RSDHSNCHNIQTNDTAKTTFQEYPLIKNCFTPQTGLSDIMKESGVDIYHYGRDRICTKGL
  EAPLQQKRAEMFLSQFNRYNENVDYCRYPEYVHPNKAKLNKCSNFSVQDSKKLANGTPET
  PTVEADTYTKLFQVKPANQKKMEETIPDQQNFTFPKTTPHLTEKQFAKEAVFTADFGLTS
  EYGLKPHTACPANDFANVTEKQQFAKPDPPHSEYFKSVNLLSNSATSSGGINLNRPTWMN
  VQTKNNTPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTPNSNLFQKYCQENP
  SAFSSFDFSYSGAERIQSVNHIEGLTKPGEENLFKLVTDKKIKQPNGFCDNYSAQKYGII
  ENVNKHNFQAKPQSGHYDPEEGPKHLDGLSQNTYQDLLESQGHSNSHRTRGGDNSRVNRT
  QVSCFSNNYMMGDLRHNQCFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLLSYDDLSHLYP
  YFNMMYGDNSFSGLMPTFGFQRPIKTRSGPASELHIRLEECCEQWRALEKERKKTELALA
  KNYPGKKVSSTNNTPVPRLTSNPSRVDRLIVDELRELARVVTLLGKMERLRSSLLHASIS
  TALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALASAIKEMCVATRKTRT
  ALWCALQMTLPKTASTADVVKPLQDTVNCEDKVHESINSSNPMNQRGETNKH

• Sequence length: 952

Related Genes

No strongly related genes found yet for MEIOC.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MEIOC.