MBLAC2 (metallo-beta-lactamase domain containing 2)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 153364
• Gene name: Metallo-beta-lactamase domain containing 2
• Gene symbol: MBLAC2
• Synonyms (NCBI Gene): -
• Chromosome: 5
• Chromosome location: 5q14.3

miRNA Show/Hide all (119)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020679	hsa-miR-155-5p	Proteomics	18668040
MIRT038924	hsa-miR-92a-1-5p	CLASH	23622248
MIRT544920	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT544919	hsa-miR-570-3p	PAR-CLIP	21572407
MIRT544920	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT544919	hsa-miR-570-3p	PAR-CLIP	21572407
MIRT1135286	hsa-miR-1197	CLIP-seq
MIRT1135287	hsa-miR-1271	CLIP-seq
MIRT1135288	hsa-miR-1279	CLIP-seq
MIRT1135289	hsa-miR-1305	CLIP-seq
MIRT1135290	hsa-miR-181a	CLIP-seq
MIRT1135291	hsa-miR-181b	CLIP-seq
MIRT1135292	hsa-miR-181c	CLIP-seq
MIRT1135293	hsa-miR-181d	CLIP-seq
MIRT1135294	hsa-miR-182	CLIP-seq
MIRT1135295	hsa-miR-205	CLIP-seq
MIRT1135296	hsa-miR-21	CLIP-seq
MIRT1135297	hsa-miR-214	CLIP-seq
MIRT1135298	hsa-miR-2277-3p	CLIP-seq
MIRT1135299	hsa-miR-2278	CLIP-seq
MIRT1135300	hsa-miR-23a	CLIP-seq
MIRT1135301	hsa-miR-23b	CLIP-seq
MIRT1135302	hsa-miR-23c	CLIP-seq
MIRT1135303	hsa-miR-3121-3p	CLIP-seq
MIRT1135304	hsa-miR-3619-5p	CLIP-seq
MIRT1135305	hsa-miR-3973	CLIP-seq
MIRT1135306	hsa-miR-4262	CLIP-seq
MIRT1135307	hsa-miR-4291	CLIP-seq
MIRT1135308	hsa-miR-4470	CLIP-seq
MIRT1135309	hsa-miR-450b-5p	CLIP-seq
MIRT1135310	hsa-miR-4511	CLIP-seq
MIRT1135311	hsa-miR-4668-3p	CLIP-seq
MIRT1135312	hsa-miR-4775	CLIP-seq
MIRT1135313	hsa-miR-4777-5p	CLIP-seq
MIRT1135314	hsa-miR-500a	CLIP-seq
MIRT1135315	hsa-miR-507	CLIP-seq
MIRT1135316	hsa-miR-513c	CLIP-seq
MIRT1135317	hsa-miR-514b-5p	CLIP-seq
MIRT1135318	hsa-miR-518d-5p	CLIP-seq
MIRT1135319	hsa-miR-519b-5p	CLIP-seq
MIRT1135320	hsa-miR-519c-5p	CLIP-seq
MIRT1135321	hsa-miR-520c-5p	CLIP-seq
MIRT1135322	hsa-miR-526a	CLIP-seq
MIRT1135323	hsa-miR-548b-3p	CLIP-seq
MIRT1135324	hsa-miR-548c-3p	CLIP-seq
MIRT1135325	hsa-miR-548l	CLIP-seq
MIRT1135326	hsa-miR-557	CLIP-seq
MIRT1135327	hsa-miR-568	CLIP-seq
MIRT1135328	hsa-miR-590-5p	CLIP-seq
MIRT1135329	hsa-miR-605	CLIP-seq
MIRT1135330	hsa-miR-616	CLIP-seq
MIRT1135331	hsa-miR-656	CLIP-seq
MIRT1135332	hsa-miR-657	CLIP-seq
MIRT1135333	hsa-miR-761	CLIP-seq
MIRT1135334	hsa-miR-922	CLIP-seq
MIRT1135335	hsa-miR-935	CLIP-seq
MIRT1135336	hsa-miR-944	CLIP-seq
MIRT1135337	hsa-miR-96	CLIP-seq
MIRT1135287	hsa-miR-1271	CLIP-seq
MIRT1135295	hsa-miR-205	CLIP-seq
MIRT1135297	hsa-miR-214	CLIP-seq
MIRT2038447	hsa-miR-302f	CLIP-seq
MIRT2038448	hsa-miR-3074-3p	CLIP-seq
MIRT2038449	hsa-miR-3192	CLIP-seq
MIRT1135304	hsa-miR-3619-5p	CLIP-seq
MIRT2038450	hsa-miR-3907	CLIP-seq
MIRT2038451	hsa-miR-3942-3p	CLIP-seq
MIRT2038452	hsa-miR-4277	CLIP-seq
MIRT1135307	hsa-miR-4291	CLIP-seq
MIRT2038453	hsa-miR-4436b-3p	CLIP-seq
MIRT2038454	hsa-miR-4457	CLIP-seq
MIRT1135310	hsa-miR-4511	CLIP-seq
MIRT2038455	hsa-miR-4724-3p	CLIP-seq
MIRT2038456	hsa-miR-4724-5p	CLIP-seq
MIRT2038457	hsa-miR-4731-3p	CLIP-seq
MIRT2038458	hsa-miR-4731-5p	CLIP-seq
MIRT1135312	hsa-miR-4775	CLIP-seq
MIRT2038459	hsa-miR-4789-5p	CLIP-seq
MIRT2038460	hsa-miR-4801	CLIP-seq
MIRT1135314	hsa-miR-500a	CLIP-seq
MIRT1135323	hsa-miR-548b-3p	CLIP-seq
MIRT2038461	hsa-miR-590-3p	CLIP-seq
MIRT1135329	hsa-miR-605	CLIP-seq
MIRT2038462	hsa-miR-624	CLIP-seq
MIRT1135332	hsa-miR-657	CLIP-seq
MIRT1135333	hsa-miR-761	CLIP-seq
MIRT1135334	hsa-miR-922	CLIP-seq
MIRT1135336	hsa-miR-944	CLIP-seq
MIRT1135337	hsa-miR-96	CLIP-seq
MIRT1135287	hsa-miR-1271	CLIP-seq
MIRT1135288	hsa-miR-1279	CLIP-seq
MIRT1135290	hsa-miR-181a	CLIP-seq
MIRT1135291	hsa-miR-181b	CLIP-seq
MIRT1135292	hsa-miR-181c	CLIP-seq
MIRT1135293	hsa-miR-181d	CLIP-seq
MIRT1135294	hsa-miR-182	CLIP-seq
MIRT2268301	hsa-miR-186	CLIP-seq
MIRT1135296	hsa-miR-21	CLIP-seq
MIRT2268302	hsa-miR-2113	CLIP-seq
MIRT2268303	hsa-miR-218	CLIP-seq
MIRT1135298	hsa-miR-2277-3p	CLIP-seq
MIRT1135300	hsa-miR-23a	CLIP-seq
MIRT1135301	hsa-miR-23b	CLIP-seq
MIRT1135302	hsa-miR-23c	CLIP-seq
MIRT2038448	hsa-miR-3074-3p	CLIP-seq
MIRT2268304	hsa-miR-3120-3p	CLIP-seq
MIRT2268305	hsa-miR-3646	CLIP-seq
MIRT2268306	hsa-miR-3647-3p	CLIP-seq
MIRT2268307	hsa-miR-369-3p	CLIP-seq
MIRT1135305	hsa-miR-3973	CLIP-seq
MIRT1135306	hsa-miR-4262	CLIP-seq
MIRT1135308	hsa-miR-4470	CLIP-seq
MIRT1135310	hsa-miR-4511	CLIP-seq
MIRT1135323	hsa-miR-548b-3p	CLIP-seq
MIRT1135324	hsa-miR-548c-3p	CLIP-seq
MIRT1135325	hsa-miR-548l	CLIP-seq
MIRT2268308	hsa-miR-548p	CLIP-seq
MIRT1135328	hsa-miR-590-5p	CLIP-seq
MIRT1135337	hsa-miR-96	CLIP-seq

Gene ontology (GO) Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	33219126
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005886	Component	Plasma membrane	IDA	33219126
GO:0005886	Component	Plasma membrane	IEA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0008800	Function	Beta-lactamase activity	IDA	31434986
GO:0008800	Function	Beta-lactamase activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0052816	Function	Long-chain fatty acyl-CoA hydrolase activity	IMP	33219126
GO:0070062	Component	Extracellular exosome	HDA	20458337

Other IDs

• MIM: 620907
• HGNC: 33711
• e!Ensembl: ENSG00000176055

Protein

• UniProt ID: Q68D91
• Protein name: Acyl-coenzyme A thioesterase MBLAC2 (Acyl-CoA thioesterase MBLAC2) (EC 3.1.2.2) (Beta-lactamase MBLAC2) (EC 3.5.2.6) (Metallo-beta-lactamase domain-containing protein 2) (Palmitoyl-coenzyme A thioesterase MBLAC2)
• Protein function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:3321
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00753	Lactamase_B	27 → 231	Metallo-beta-lactamase superfamily	Domain

• Sequence:

  MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSS
  GLLQDREAKEDAARRPLLAVATHVHFDHSGGLYQFDRVAVHHAEAEALARGDNFETVTWL
  SDSEVVRTPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDK
  DRKILFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERL
  FRLASNYISKAGICHKVSTFAMRSLASLALRVTNSRTSP

• Sequence length: 279

Pathways

KEGG Pathway:

Fatty acid elongation

Related Genes

No strongly related genes found yet for MBLAC2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MBLAC2.