MATCAP1 (microtubule associated tyrosine carboxypeptidase 1)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 653319
• Gene name: Microtubule associated tyrosine carboxypeptidase 1
• Gene symbol: MATCAP1
• Synonyms (NCBI Gene): KIAA0895L, TMCP1
• Chromosome: 16
• Chromosome location: 16q22.1

miRNA Show/Hide all (257)

miRTarBase ID	miRNA	Experiments	Reference
MIRT041118	hsa-miR-503-5p	CLASH	23622248
MIRT608217	hsa-miR-4506	HITS-CLIP	23824327
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	23824327
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT608213	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT608217	hsa-miR-4506	HITS-CLIP	23824327
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	23824327
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT608213	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT608769	hsa-miR-5094	HITS-CLIP	24906430
MIRT608768	hsa-miR-6733-3p	HITS-CLIP	24906430
MIRT608767	hsa-miR-4302	HITS-CLIP	24906430
MIRT608766	hsa-miR-5187-3p	HITS-CLIP	24906430
MIRT608765	hsa-miR-15b-3p	HITS-CLIP	24906430
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT608213	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT608217	hsa-miR-4506	HITS-CLIP	24906430
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	24906430
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT608213	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT474790	hsa-miR-1296-3p	PAR-CLIP	23592263
MIRT474789	hsa-miR-922	PAR-CLIP	23592263
MIRT474788	hsa-miR-4419a	PAR-CLIP	23592263
MIRT474787	hsa-miR-4510	PAR-CLIP	23592263
MIRT474786	hsa-miR-6127	PAR-CLIP	23592263
MIRT474785	hsa-miR-6129	PAR-CLIP	23592263
MIRT474784	hsa-miR-6130	PAR-CLIP	23592263
MIRT474783	hsa-miR-6133	PAR-CLIP	23592263
MIRT474782	hsa-miR-4481	PAR-CLIP	23592263
MIRT474781	hsa-miR-4745-5p	PAR-CLIP	23592263
MIRT474780	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT474779	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT474778	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT474777	hsa-miR-4271	PAR-CLIP	23592263
MIRT474776	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT474775	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT474774	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT474773	hsa-miR-491-5p	PAR-CLIP	23592263
MIRT474772	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT474771	hsa-miR-2110	PAR-CLIP	23592263
MIRT474790	hsa-miR-1296-3p	HITS-CLIP	27418678
MIRT474790	hsa-miR-1296-3p	HITS-CLIP	27418678
MIRT474790	hsa-miR-1296-3p	HITS-CLIP	27418678
MIRT474790	hsa-miR-1296-3p	HITS-CLIP	27418678
MIRT474782	hsa-miR-4481	HITS-CLIP	27418678
MIRT474782	hsa-miR-4481	HITS-CLIP	27418678
MIRT474782	hsa-miR-4481	HITS-CLIP	27418678
MIRT474782	hsa-miR-4481	HITS-CLIP	27418678
MIRT608217	hsa-miR-4506	HITS-CLIP	27418678
MIRT608217	hsa-miR-4506	HITS-CLIP	27418678
MIRT608217	hsa-miR-4506	HITS-CLIP	27418678
MIRT608217	hsa-miR-4506	HITS-CLIP	27418678
MIRT474781	hsa-miR-4745-5p	HITS-CLIP	27418678
MIRT474781	hsa-miR-4745-5p	HITS-CLIP	27418678
MIRT474781	hsa-miR-4745-5p	HITS-CLIP	27418678
MIRT474781	hsa-miR-4745-5p	HITS-CLIP	27418678
MIRT608213	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608213	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608213	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608213	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	27418678
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	27418678
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	27418678
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	27418678
MIRT608217	hsa-miR-4506	HITS-CLIP	23824327
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	23824327
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT608213	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT608217	hsa-miR-4506	HITS-CLIP	23824327
MIRT608215	hsa-miR-6871-5p	HITS-CLIP	23824327
MIRT608214	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT608213	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT474790	hsa-miR-1296-3p	PAR-CLIP	23592263
MIRT474789	hsa-miR-922	PAR-CLIP	23592263
MIRT474788	hsa-miR-4419a	PAR-CLIP	23592263
MIRT474787	hsa-miR-4510	PAR-CLIP	23592263
MIRT474786	hsa-miR-6127	PAR-CLIP	23592263
MIRT474785	hsa-miR-6129	PAR-CLIP	23592263
MIRT474784	hsa-miR-6130	PAR-CLIP	23592263
MIRT474783	hsa-miR-6133	PAR-CLIP	23592263
MIRT474782	hsa-miR-4481	PAR-CLIP	23592263
MIRT474781	hsa-miR-4745-5p	PAR-CLIP	23592263
MIRT474780	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT474779	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT474778	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT474777	hsa-miR-4271	PAR-CLIP	23592263
MIRT474776	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT474775	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT474774	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT474773	hsa-miR-491-5p	PAR-CLIP	23592263
MIRT474772	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT474771	hsa-miR-2110	PAR-CLIP	23592263
MIRT1088363	hsa-let-7a	CLIP-seq
MIRT1088364	hsa-let-7b	CLIP-seq
MIRT1088365	hsa-let-7c	CLIP-seq
MIRT1088366	hsa-let-7d	CLIP-seq
MIRT1088367	hsa-let-7e	CLIP-seq
MIRT1088368	hsa-let-7f	CLIP-seq
MIRT1088369	hsa-let-7g	CLIP-seq
MIRT1088370	hsa-let-7i	CLIP-seq
MIRT1088371	hsa-miR-105	CLIP-seq
MIRT1088372	hsa-miR-1264	CLIP-seq
MIRT1088373	hsa-miR-198	CLIP-seq
MIRT1088374	hsa-miR-28-5p	CLIP-seq
MIRT1088375	hsa-miR-3130-5p	CLIP-seq
MIRT1088376	hsa-miR-3139	CLIP-seq
MIRT1088377	hsa-miR-3164	CLIP-seq
MIRT1088378	hsa-miR-3170	CLIP-seq
MIRT1088379	hsa-miR-3179	CLIP-seq
MIRT1088380	hsa-miR-3182	CLIP-seq
MIRT1088381	hsa-miR-345	CLIP-seq
MIRT1088382	hsa-miR-3529	CLIP-seq
MIRT1088383	hsa-miR-3688-3p	CLIP-seq
MIRT1088384	hsa-miR-377	CLIP-seq
MIRT1088385	hsa-miR-379	CLIP-seq
MIRT1088386	hsa-miR-3918	CLIP-seq
MIRT1088387	hsa-miR-3927	CLIP-seq
MIRT1088388	hsa-miR-3941	CLIP-seq
MIRT1088389	hsa-miR-411	CLIP-seq
MIRT1088390	hsa-miR-4256	CLIP-seq
MIRT1088391	hsa-miR-4433	CLIP-seq
MIRT1088392	hsa-miR-4436a	CLIP-seq
MIRT1088393	hsa-miR-4458	CLIP-seq
MIRT1088394	hsa-miR-4459	CLIP-seq
MIRT1088395	hsa-miR-4482	CLIP-seq
MIRT1088396	hsa-miR-4500	CLIP-seq
MIRT1088397	hsa-miR-4512	CLIP-seq
MIRT1088398	hsa-miR-4640-5p	CLIP-seq
MIRT1088399	hsa-miR-466	CLIP-seq
MIRT1088400	hsa-miR-4672	CLIP-seq
MIRT1088401	hsa-miR-4685-5p	CLIP-seq
MIRT1088402	hsa-miR-4691-3p	CLIP-seq
MIRT1088403	hsa-miR-4719	CLIP-seq
MIRT1088404	hsa-miR-4726-5p	CLIP-seq
MIRT1088405	hsa-miR-4728-3p	CLIP-seq
MIRT1088406	hsa-miR-4731-3p	CLIP-seq
MIRT1088407	hsa-miR-4757-5p	CLIP-seq
MIRT1088408	hsa-miR-4768-3p	CLIP-seq
MIRT1088409	hsa-miR-4801	CLIP-seq
MIRT1088410	hsa-miR-558	CLIP-seq
MIRT1088411	hsa-miR-618	CLIP-seq
MIRT1088412	hsa-miR-635	CLIP-seq
MIRT1088413	hsa-miR-708	CLIP-seq
MIRT1088414	hsa-miR-711	CLIP-seq
MIRT1088415	hsa-miR-873	CLIP-seq
MIRT1088416	hsa-miR-98	CLIP-seq
MIRT2023375	hsa-miR-4268	CLIP-seq
MIRT1088392	hsa-miR-4436a	CLIP-seq
MIRT2023376	hsa-miR-4448	CLIP-seq
MIRT1088398	hsa-miR-4640-5p	CLIP-seq
MIRT2023377	hsa-miR-4722-3p	CLIP-seq
MIRT1088404	hsa-miR-4726-5p	CLIP-seq
MIRT1088412	hsa-miR-635	CLIP-seq
MIRT1088363	hsa-let-7a	CLIP-seq
MIRT1088364	hsa-let-7b	CLIP-seq
MIRT1088365	hsa-let-7c	CLIP-seq
MIRT1088366	hsa-let-7d	CLIP-seq
MIRT1088367	hsa-let-7e	CLIP-seq
MIRT1088368	hsa-let-7f	CLIP-seq
MIRT1088369	hsa-let-7g	CLIP-seq
MIRT1088370	hsa-let-7i	CLIP-seq
MIRT2254229	hsa-miR-122	CLIP-seq
MIRT2254230	hsa-miR-1284	CLIP-seq
MIRT2254231	hsa-miR-15a	CLIP-seq
MIRT2254232	hsa-miR-15b	CLIP-seq
MIRT2254233	hsa-miR-16	CLIP-seq
MIRT2254234	hsa-miR-195	CLIP-seq
MIRT1088374	hsa-miR-28-5p	CLIP-seq
MIRT2254235	hsa-miR-3130-3p	CLIP-seq
MIRT1088375	hsa-miR-3130-5p	CLIP-seq
MIRT1088376	hsa-miR-3139	CLIP-seq
MIRT2254236	hsa-miR-3154	CLIP-seq
MIRT1088382	hsa-miR-3529	CLIP-seq
MIRT2254237	hsa-miR-3622a-3p	CLIP-seq
MIRT2254238	hsa-miR-3622b-3p	CLIP-seq
MIRT2254239	hsa-miR-3663-5p	CLIP-seq
MIRT1088385	hsa-miR-379	CLIP-seq
MIRT2254240	hsa-miR-3926	CLIP-seq
MIRT1088387	hsa-miR-3927	CLIP-seq
MIRT1088388	hsa-miR-3941	CLIP-seq
MIRT2254241	hsa-miR-424	CLIP-seq
MIRT2254242	hsa-miR-4421	CLIP-seq
MIRT1088391	hsa-miR-4433	CLIP-seq
MIRT2254243	hsa-miR-4434	CLIP-seq
MIRT1088392	hsa-miR-4436a	CLIP-seq
MIRT1088393	hsa-miR-4458	CLIP-seq
MIRT1088394	hsa-miR-4459	CLIP-seq
MIRT1088395	hsa-miR-4482	CLIP-seq
MIRT2254244	hsa-miR-4484	CLIP-seq
MIRT1088396	hsa-miR-4500	CLIP-seq
MIRT2254245	hsa-miR-4516	CLIP-seq
MIRT1088398	hsa-miR-4640-5p	CLIP-seq
MIRT1088399	hsa-miR-466	CLIP-seq
MIRT1088400	hsa-miR-4672	CLIP-seq
MIRT2254246	hsa-miR-4682	CLIP-seq
MIRT1088402	hsa-miR-4691-3p	CLIP-seq
MIRT1088403	hsa-miR-4719	CLIP-seq
MIRT1088404	hsa-miR-4726-5p	CLIP-seq
MIRT1088406	hsa-miR-4731-3p	CLIP-seq
MIRT2254247	hsa-miR-4733-3p	CLIP-seq
MIRT2254248	hsa-miR-4738-3p	CLIP-seq
MIRT2254249	hsa-miR-4753-5p	CLIP-seq
MIRT1088408	hsa-miR-4768-3p	CLIP-seq
MIRT2254250	hsa-miR-4793-3p	CLIP-seq
MIRT1088409	hsa-miR-4801	CLIP-seq
MIRT2254251	hsa-miR-497	CLIP-seq
MIRT2254252	hsa-miR-524-3p	CLIP-seq
MIRT2254253	hsa-miR-525-3p	CLIP-seq
MIRT1088410	hsa-miR-558	CLIP-seq
MIRT2254254	hsa-miR-601	CLIP-seq
MIRT1088412	hsa-miR-635	CLIP-seq
MIRT2254255	hsa-miR-656	CLIP-seq
MIRT2254256	hsa-miR-665	CLIP-seq
MIRT2254257	hsa-miR-671-5p	CLIP-seq
MIRT1088413	hsa-miR-708	CLIP-seq
MIRT1088414	hsa-miR-711	CLIP-seq
MIRT1088416	hsa-miR-98	CLIP-seq
MIRT2254230	hsa-miR-1284	CLIP-seq
MIRT2556689	hsa-miR-1972	CLIP-seq
MIRT2556690	hsa-miR-24	CLIP-seq
MIRT2556691	hsa-miR-3155	CLIP-seq
MIRT2556692	hsa-miR-3155b	CLIP-seq
MIRT1088388	hsa-miR-3941	CLIP-seq
MIRT2254244	hsa-miR-4484	CLIP-seq
MIRT2556693	hsa-miR-4529-5p	CLIP-seq
MIRT2556694	hsa-miR-4650-5p	CLIP-seq
MIRT1088399	hsa-miR-466	CLIP-seq
MIRT1088400	hsa-miR-4672	CLIP-seq
MIRT2556695	hsa-miR-4705	CLIP-seq
MIRT1088406	hsa-miR-4731-3p	CLIP-seq
MIRT1088409	hsa-miR-4801	CLIP-seq
MIRT2556696	hsa-miR-484	CLIP-seq
MIRT2254252	hsa-miR-524-3p	CLIP-seq
MIRT2254253	hsa-miR-525-3p	CLIP-seq
MIRT1088371	hsa-miR-105	CLIP-seq
MIRT2683358	hsa-miR-1252	CLIP-seq
MIRT2254230	hsa-miR-1284	CLIP-seq
MIRT2683359	hsa-miR-3646	CLIP-seq
MIRT2683360	hsa-miR-369-3p	CLIP-seq
MIRT2683361	hsa-miR-374a	CLIP-seq
MIRT2683362	hsa-miR-374b	CLIP-seq
MIRT1088388	hsa-miR-3941	CLIP-seq
MIRT2254244	hsa-miR-4484	CLIP-seq
MIRT1088399	hsa-miR-466	CLIP-seq
MIRT1088400	hsa-miR-4672	CLIP-seq
MIRT1088403	hsa-miR-4719	CLIP-seq
MIRT1088405	hsa-miR-4728-3p	CLIP-seq
MIRT1088406	hsa-miR-4731-3p	CLIP-seq
MIRT2683363	hsa-miR-4790-5p	CLIP-seq
MIRT1088409	hsa-miR-4801	CLIP-seq
MIRT2254252	hsa-miR-524-3p	CLIP-seq
MIRT2254253	hsa-miR-525-3p	CLIP-seq
MIRT2254255	hsa-miR-656	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004180	Function	Carboxypeptidase activity	IEA
GO:0004181	Function	Metallocarboxypeptidase activity	IDA	35482892
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IDA	35482892
GO:0006508	Process	Proteolysis	IEA
GO:0007420	Process	Brain development	IEA
GO:0007420	Process	Brain development	ISS
GO:0008233	Function	Peptidase activity	IEA
GO:0008237	Function	Metallopeptidase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0106423	Function	Tubulin-tyrosine carboxypeptidase	IDA	35482892

Other IDs

• MIM: 619978
• HGNC: 34408
• e!Ensembl: ENSG00000196123

Protein

• UniProt ID: Q68EN5
• Protein name: Microtubule-associated tyrosine carboxypeptidase 1 (EC 3.4.17.17) (Microtubule-associated tyrosine carboxypeptidase)
• Protein function: Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:35482892). Also able to remove the C-terminal phenylalanine residue of alpha-tubulin TUBA8 (Pub
• PDB: 7Z5G , 7Z5H , 7Z6S
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08014	DUF1704	177 → 460	Domain of unknown function (DUF1704)	Domain

• Sequence:

  MVLDSGAQAYDQAPPSPPTSPPSLRHRLKPSDRDGPPLYPWSQSLALPLALAVPPALQPQ
  PEQQPFSQMLLGHRGHMRRSESTYSVNSTGRRGRGTLGRPPPGRGRNPGGGTLRPAASLP
  HIAKTQRDAGHIASKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKY
  CEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCAGEVV
  VQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNARQPWHNA
  EGRLRYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLERY
  VQDADVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSY
  EDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMATNRLDEAELGRLLPD

• Sequence length: 471

Related Genes

No strongly related genes found yet for MATCAP1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MATCAP1.