MAN1C1 (mannosidase alpha class 1C member 1)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57134
• Gene name: Mannosidase alpha class 1C member 1
• Gene symbol: MAN1C1
• Synonyms (NCBI Gene): HMIC, MAN1A3, MAN1C, pp6318
• Chromosome: 1
• Chromosome location: 1p36.11

miRNA Show/Hide all (345)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020204	hsa-miR-130b-3p	Sequencing	20371350
MIRT028164	hsa-miR-93-5p	Sequencing	20371350
MIRT050567	hsa-miR-20a-5p	CLASH	23622248
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT623323	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	27418678
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	27418678
MIRT623327	hsa-miR-552-3p	HITS-CLIP	27418678
MIRT623327	hsa-miR-552-3p	HITS-CLIP	27418678
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	27418678
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	27418678
MIRT623324	hsa-miR-8055	HITS-CLIP	27418678
MIRT623324	hsa-miR-8055	HITS-CLIP	27418678
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT2036049	hsa-miR-4420	CLIP-seq
MIRT2036050	hsa-miR-554	CLIP-seq
MIRT2036051	hsa-miR-570	CLIP-seq
MIRT2390489	hsa-miR-1915	CLIP-seq
MIRT2390490	hsa-miR-3141	CLIP-seq
MIRT2390491	hsa-miR-4685-5p	CLIP-seq
MIRT2565551	hsa-miR-1	CLIP-seq
MIRT2565552	hsa-miR-106a	CLIP-seq
MIRT2565553	hsa-miR-106b	CLIP-seq
MIRT2565554	hsa-miR-1182	CLIP-seq
MIRT2565555	hsa-miR-1183	CLIP-seq
MIRT2565556	hsa-miR-1207-5p	CLIP-seq
MIRT2565557	hsa-miR-1264	CLIP-seq
MIRT2565558	hsa-miR-1273f	CLIP-seq
MIRT2565559	hsa-miR-1291	CLIP-seq
MIRT2565560	hsa-miR-132	CLIP-seq
MIRT2565561	hsa-miR-1323	CLIP-seq
MIRT2565562	hsa-miR-141	CLIP-seq
MIRT2565563	hsa-miR-146a	CLIP-seq
MIRT2565564	hsa-miR-147	CLIP-seq
MIRT2565565	hsa-miR-1587	CLIP-seq
MIRT2565566	hsa-miR-17	CLIP-seq
MIRT2565567	hsa-miR-188-5p	CLIP-seq
MIRT2565568	hsa-miR-1909	CLIP-seq
MIRT2565569	hsa-miR-1913	CLIP-seq
MIRT2390489	hsa-miR-1915	CLIP-seq
MIRT2565570	hsa-miR-19a	CLIP-seq
MIRT2565571	hsa-miR-19b	CLIP-seq
MIRT2565572	hsa-miR-200a	CLIP-seq
MIRT2565573	hsa-miR-204	CLIP-seq
MIRT2565574	hsa-miR-206	CLIP-seq
MIRT2565575	hsa-miR-20a	CLIP-seq
MIRT2565576	hsa-miR-20b	CLIP-seq
MIRT2565577	hsa-miR-211	CLIP-seq
MIRT2565578	hsa-miR-2113	CLIP-seq
MIRT2565579	hsa-miR-212	CLIP-seq
MIRT2565580	hsa-miR-300	CLIP-seq
MIRT2565581	hsa-miR-31	CLIP-seq
MIRT2565582	hsa-miR-3121-5p	CLIP-seq
MIRT2565583	hsa-miR-3123	CLIP-seq
MIRT2565584	hsa-miR-3125	CLIP-seq
MIRT2565585	hsa-miR-3140-5p	CLIP-seq
MIRT2390490	hsa-miR-3141	CLIP-seq
MIRT2565586	hsa-miR-3147	CLIP-seq
MIRT2565587	hsa-miR-3152-5p	CLIP-seq
MIRT2565588	hsa-miR-3174	CLIP-seq
MIRT2565589	hsa-miR-3180	CLIP-seq
MIRT2565590	hsa-miR-3180-3p	CLIP-seq
MIRT2565591	hsa-miR-3196	CLIP-seq
MIRT2565592	hsa-miR-3201	CLIP-seq
MIRT2565593	hsa-miR-324-3p	CLIP-seq
MIRT2565594	hsa-miR-324-5p	CLIP-seq
MIRT2565595	hsa-miR-328	CLIP-seq
MIRT2565596	hsa-miR-342-5p	CLIP-seq
MIRT2565597	hsa-miR-346	CLIP-seq
MIRT2565598	hsa-miR-3655	CLIP-seq
MIRT2565599	hsa-miR-3671	CLIP-seq
MIRT2565600	hsa-miR-3673	CLIP-seq
MIRT2565601	hsa-miR-3675-5p	CLIP-seq
MIRT2565602	hsa-miR-3691-3p	CLIP-seq
MIRT2565603	hsa-miR-371-5p	CLIP-seq
MIRT2565604	hsa-miR-371b-5p	CLIP-seq
MIRT2565605	hsa-miR-381	CLIP-seq
MIRT2565606	hsa-miR-3910	CLIP-seq
MIRT2565607	hsa-miR-3913-3p	CLIP-seq
MIRT2565608	hsa-miR-3916	CLIP-seq
MIRT2565609	hsa-miR-3925-5p	CLIP-seq
MIRT2565610	hsa-miR-3960	CLIP-seq
MIRT2565611	hsa-miR-425	CLIP-seq
MIRT2565612	hsa-miR-4268	CLIP-seq
MIRT2565613	hsa-miR-4269	CLIP-seq
MIRT2565614	hsa-miR-4279	CLIP-seq
MIRT2565615	hsa-miR-4302	CLIP-seq
MIRT2565616	hsa-miR-4308	CLIP-seq
MIRT2565617	hsa-miR-4422	CLIP-seq
MIRT2565618	hsa-miR-4425	CLIP-seq
MIRT2565619	hsa-miR-4435	CLIP-seq
MIRT2565620	hsa-miR-4448	CLIP-seq
MIRT2565621	hsa-miR-4467	CLIP-seq
MIRT2565622	hsa-miR-4481	CLIP-seq
MIRT2565623	hsa-miR-4492	CLIP-seq
MIRT2565624	hsa-miR-4498	CLIP-seq
MIRT2565625	hsa-miR-4504	CLIP-seq
MIRT2565626	hsa-miR-4514	CLIP-seq
MIRT2565627	hsa-miR-4527	CLIP-seq
MIRT2565628	hsa-miR-4649-5p	CLIP-seq
MIRT2565629	hsa-miR-4651	CLIP-seq
MIRT2565630	hsa-miR-4656	CLIP-seq
MIRT2565631	hsa-miR-4664-5p	CLIP-seq
MIRT2565632	hsa-miR-4674	CLIP-seq
MIRT2565633	hsa-miR-4675	CLIP-seq
MIRT2390491	hsa-miR-4685-5p	CLIP-seq
MIRT2565634	hsa-miR-4686	CLIP-seq
MIRT2565635	hsa-miR-4692	CLIP-seq
MIRT2565636	hsa-miR-4697-3p	CLIP-seq
MIRT2565637	hsa-miR-4708-3p	CLIP-seq
MIRT2565638	hsa-miR-4731-5p	CLIP-seq
MIRT2565639	hsa-miR-4732-5p	CLIP-seq
MIRT2565640	hsa-miR-4740-3p	CLIP-seq
MIRT2565641	hsa-miR-4741	CLIP-seq
MIRT2565642	hsa-miR-4742-5p	CLIP-seq
MIRT2565643	hsa-miR-4745-5p	CLIP-seq
MIRT2565644	hsa-miR-4758-5p	CLIP-seq
MIRT2565645	hsa-miR-4762-5p	CLIP-seq
MIRT2565646	hsa-miR-4763-3p	CLIP-seq
MIRT2565647	hsa-miR-4768-3p	CLIP-seq
MIRT2565648	hsa-miR-4773	CLIP-seq
MIRT2565649	hsa-miR-4774-3p	CLIP-seq
MIRT2565650	hsa-miR-4791	CLIP-seq
MIRT2565651	hsa-miR-489	CLIP-seq
MIRT2565652	hsa-miR-515-5p	CLIP-seq
MIRT2565653	hsa-miR-519a	CLIP-seq
MIRT2565654	hsa-miR-519b-3p	CLIP-seq
MIRT2565655	hsa-miR-519c-3p	CLIP-seq
MIRT2565656	hsa-miR-519d	CLIP-seq
MIRT2565657	hsa-miR-542-3p	CLIP-seq
MIRT2565658	hsa-miR-548aa	CLIP-seq
MIRT2565659	hsa-miR-548ac	CLIP-seq
MIRT2565660	hsa-miR-548an	CLIP-seq
MIRT2565661	hsa-miR-548d-3p	CLIP-seq
MIRT2565662	hsa-miR-548g	CLIP-seq
MIRT2565663	hsa-miR-548o	CLIP-seq
MIRT2565664	hsa-miR-548p	CLIP-seq
MIRT2565665	hsa-miR-548z	CLIP-seq
MIRT2036051	hsa-miR-570	CLIP-seq
MIRT2565666	hsa-miR-577	CLIP-seq
MIRT2565667	hsa-miR-580	CLIP-seq
MIRT2565668	hsa-miR-589	CLIP-seq
MIRT2565669	hsa-miR-599	CLIP-seq
MIRT2565670	hsa-miR-608	CLIP-seq
MIRT2565671	hsa-miR-613	CLIP-seq
MIRT2565672	hsa-miR-624	CLIP-seq
MIRT2565673	hsa-miR-627	CLIP-seq
MIRT2565674	hsa-miR-629	CLIP-seq
MIRT2565675	hsa-miR-637	CLIP-seq
MIRT2565676	hsa-miR-642b	CLIP-seq
MIRT2565677	hsa-miR-758	CLIP-seq
MIRT2565678	hsa-miR-762	CLIP-seq
MIRT2565679	hsa-miR-924	CLIP-seq
MIRT2565680	hsa-miR-93	CLIP-seq
MIRT2565552	hsa-miR-106a	CLIP-seq
MIRT2565553	hsa-miR-106b	CLIP-seq
MIRT2565554	hsa-miR-1182	CLIP-seq
MIRT2565555	hsa-miR-1183	CLIP-seq
MIRT2565556	hsa-miR-1207-5p	CLIP-seq
MIRT2565557	hsa-miR-1264	CLIP-seq
MIRT2565558	hsa-miR-1273f	CLIP-seq
MIRT2565560	hsa-miR-132	CLIP-seq
MIRT2565561	hsa-miR-1323	CLIP-seq
MIRT2565562	hsa-miR-141	CLIP-seq
MIRT2565563	hsa-miR-146a	CLIP-seq
MIRT2565564	hsa-miR-147	CLIP-seq
MIRT2565565	hsa-miR-1587	CLIP-seq
MIRT2565566	hsa-miR-17	CLIP-seq
MIRT2565567	hsa-miR-188-5p	CLIP-seq
MIRT2565568	hsa-miR-1909	CLIP-seq
MIRT2565569	hsa-miR-1913	CLIP-seq
MIRT2390489	hsa-miR-1915	CLIP-seq
MIRT2565570	hsa-miR-19a	CLIP-seq
MIRT2565571	hsa-miR-19b	CLIP-seq
MIRT2565572	hsa-miR-200a	CLIP-seq
MIRT2565573	hsa-miR-204	CLIP-seq
MIRT2565575	hsa-miR-20a	CLIP-seq
MIRT2565576	hsa-miR-20b	CLIP-seq
MIRT2565577	hsa-miR-211	CLIP-seq
MIRT2565578	hsa-miR-2113	CLIP-seq
MIRT2565579	hsa-miR-212	CLIP-seq
MIRT2565580	hsa-miR-300	CLIP-seq
MIRT2565582	hsa-miR-3121-5p	CLIP-seq
MIRT2565583	hsa-miR-3123	CLIP-seq
MIRT2565584	hsa-miR-3125	CLIP-seq
MIRT2565585	hsa-miR-3140-5p	CLIP-seq
MIRT2390490	hsa-miR-3141	CLIP-seq
MIRT2565586	hsa-miR-3147	CLIP-seq
MIRT2565587	hsa-miR-3152-5p	CLIP-seq
MIRT2565589	hsa-miR-3180	CLIP-seq
MIRT2565590	hsa-miR-3180-3p	CLIP-seq
MIRT2565591	hsa-miR-3196	CLIP-seq
MIRT2565592	hsa-miR-3201	CLIP-seq
MIRT2565593	hsa-miR-324-3p	CLIP-seq
MIRT2565594	hsa-miR-324-5p	CLIP-seq
MIRT2565596	hsa-miR-342-5p	CLIP-seq
MIRT2565597	hsa-miR-346	CLIP-seq
MIRT2565598	hsa-miR-3655	CLIP-seq
MIRT2565599	hsa-miR-3671	CLIP-seq
MIRT2565601	hsa-miR-3675-5p	CLIP-seq
MIRT2565602	hsa-miR-3691-3p	CLIP-seq
MIRT2565603	hsa-miR-371-5p	CLIP-seq
MIRT2565604	hsa-miR-371b-5p	CLIP-seq
MIRT2565605	hsa-miR-381	CLIP-seq
MIRT2565606	hsa-miR-3910	CLIP-seq
MIRT2565607	hsa-miR-3913-3p	CLIP-seq
MIRT2565608	hsa-miR-3916	CLIP-seq
MIRT2565609	hsa-miR-3925-5p	CLIP-seq
MIRT2565610	hsa-miR-3960	CLIP-seq
MIRT2565611	hsa-miR-425	CLIP-seq
MIRT2565613	hsa-miR-4269	CLIP-seq
MIRT2565614	hsa-miR-4279	CLIP-seq
MIRT2565615	hsa-miR-4302	CLIP-seq
MIRT2565617	hsa-miR-4422	CLIP-seq
MIRT2565618	hsa-miR-4425	CLIP-seq
MIRT2565619	hsa-miR-4435	CLIP-seq
MIRT2565621	hsa-miR-4467	CLIP-seq
MIRT2565623	hsa-miR-4492	CLIP-seq
MIRT2565624	hsa-miR-4498	CLIP-seq
MIRT2565625	hsa-miR-4504	CLIP-seq
MIRT2565626	hsa-miR-4514	CLIP-seq
MIRT2565627	hsa-miR-4527	CLIP-seq
MIRT2565628	hsa-miR-4649-5p	CLIP-seq
MIRT2565629	hsa-miR-4651	CLIP-seq
MIRT2565630	hsa-miR-4656	CLIP-seq
MIRT2565631	hsa-miR-4664-5p	CLIP-seq
MIRT2565632	hsa-miR-4674	CLIP-seq
MIRT2565633	hsa-miR-4675	CLIP-seq
MIRT2390491	hsa-miR-4685-5p	CLIP-seq
MIRT2565634	hsa-miR-4686	CLIP-seq
MIRT2565635	hsa-miR-4692	CLIP-seq
MIRT2565636	hsa-miR-4697-3p	CLIP-seq
MIRT2565637	hsa-miR-4708-3p	CLIP-seq
MIRT2565638	hsa-miR-4731-5p	CLIP-seq
MIRT2565639	hsa-miR-4732-5p	CLIP-seq
MIRT2565640	hsa-miR-4740-3p	CLIP-seq
MIRT2565641	hsa-miR-4741	CLIP-seq
MIRT2565642	hsa-miR-4742-5p	CLIP-seq
MIRT2565645	hsa-miR-4762-5p	CLIP-seq
MIRT2565646	hsa-miR-4763-3p	CLIP-seq
MIRT2565647	hsa-miR-4768-3p	CLIP-seq
MIRT2565648	hsa-miR-4773	CLIP-seq
MIRT2565649	hsa-miR-4774-3p	CLIP-seq
MIRT2565650	hsa-miR-4791	CLIP-seq
MIRT2565651	hsa-miR-489	CLIP-seq
MIRT2565652	hsa-miR-515-5p	CLIP-seq
MIRT2565653	hsa-miR-519a	CLIP-seq
MIRT2565654	hsa-miR-519b-3p	CLIP-seq
MIRT2565655	hsa-miR-519c-3p	CLIP-seq
MIRT2565656	hsa-miR-519d	CLIP-seq
MIRT2565657	hsa-miR-542-3p	CLIP-seq
MIRT2565658	hsa-miR-548aa	CLIP-seq
MIRT2565659	hsa-miR-548ac	CLIP-seq
MIRT2565660	hsa-miR-548an	CLIP-seq
MIRT2565661	hsa-miR-548d-3p	CLIP-seq
MIRT2565662	hsa-miR-548g	CLIP-seq
MIRT2565663	hsa-miR-548o	CLIP-seq
MIRT2565664	hsa-miR-548p	CLIP-seq
MIRT2565665	hsa-miR-548z	CLIP-seq
MIRT2036051	hsa-miR-570	CLIP-seq
MIRT2565666	hsa-miR-577	CLIP-seq
MIRT2565667	hsa-miR-580	CLIP-seq
MIRT2565668	hsa-miR-589	CLIP-seq
MIRT2565669	hsa-miR-599	CLIP-seq
MIRT2565670	hsa-miR-608	CLIP-seq
MIRT2565672	hsa-miR-624	CLIP-seq
MIRT2565673	hsa-miR-627	CLIP-seq
MIRT2565674	hsa-miR-629	CLIP-seq
MIRT2565675	hsa-miR-637	CLIP-seq
MIRT2565676	hsa-miR-642b	CLIP-seq
MIRT2565677	hsa-miR-758	CLIP-seq
MIRT2565678	hsa-miR-762	CLIP-seq
MIRT2565679	hsa-miR-924	CLIP-seq
MIRT2565680	hsa-miR-93	CLIP-seq

Gene ontology (GO) Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IBA
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS	10915796
GO:0004571	Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IBA
GO:0004571	Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IEA
GO:0004571	Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	TAS	10915796
GO:0005509	Function	Calcium ion binding	IEA
GO:0005509	Function	Calcium ion binding	TAS	10915796
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005975	Process	Carbohydrate metabolic process	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006487	Process	Protein N-linked glycosylation	TAS	10915796
GO:0006491	Process	N-glycan processing	IEA
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016798	Function	Hydrolase activity, acting on glycosyl bonds	IEA
GO:0036503	Process	ERAD pathway	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:1904381	Process	Golgi apparatus mannose trimming	TAS

Other IDs

• MIM: 616772
• HGNC: 19080
• e!Ensembl: ENSG00000117643

Protein

• UniProt ID: Q9NR34
• Protein name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (EC 3.2.1.113) (HMIC) (Mannosidase alpha class 1C member 1) (Processing alpha-1,2-mannosidase IC) (Alpha-1,2-mannosidase IC)
• Protein function: Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01532	Glyco_hydro_47	181 → 617	Glycosyl hydrolase family 47	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta.
• Sequence:

  MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQ
  PGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREE
  ATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKE
  MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK
  AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTG
  IPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI
  EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA
  IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ
  ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI
  YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL
  LSLEDWVFNTEAHPLPVNHSDSSGRAWGRH

• Sequence length: 630

Pathways

KEGG Pathway	Reactome Pathway
N-Glycan biosynthesis	Intra-Golgi traffic
Various types of N-glycan biosynthesis	Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
Metabolic pathways
Protein processing in endoplasmic reticulum

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
MAN1C1-related disorder	Likely benign; Benign; Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (15)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinogenesis	Carcinogenesis	Pubtator	38117655	Associate	★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	38117655	Associate	★☆☆☆☆ Found in Text Mining only
Common Variable Immunodeficiency	Common Variable Immunodeficiency	GWASDB_DG	21497890		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	30588245		★☆☆☆☆ Found in Text Mining only
Emphysema	Emphysema	Pubtator	24383474	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	39333557	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	39333557	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25455875, 30588245		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	39972314	Associate	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	26510930	Associate	★☆☆☆☆ Found in Text Mining only
Pulmonary Emphysema	Pulmonary Emphysema	BEFREE	24383474		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	30588245		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	27557994		★☆☆☆☆ Found in Text Mining only
Sleep Apnea, Obstructive	Sleep Apnea	BEFREE	28543355		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	35065254	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

MAN1A2 5 shared pathwaysN-Glycan biosynthesis, Various types of N-glycan biosynthesis, Protein processing in endoplasmic reticulum, Intra-Golgi traffic, Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 Related via 5 shared pathways including N-Glycan biosynthesis, Various types of N-glycan biosynthesis. MAN1A1 5 shared pathwaysN-Glycan biosynthesis, Various types of N-glycan biosynthesis, Protein processing in endoplasmic reticulum, Intra-Golgi traffic, Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 Related via 5 shared pathways including N-Glycan biosynthesis, Various types of N-glycan biosynthesis. KRTCAP2 3 shared pathwaysN-Glycan biosynthesis, Various types of N-glycan biosynthesis, Protein processing in endoplasmic reticulum Related via 3 shared pathways including N-Glycan biosynthesis, Various types of N-glycan biosynthesis. STT3B 3 shared pathwaysN-Glycan biosynthesis, Various types of N-glycan biosynthesis, Protein processing in endoplasmic reticulum Related via 3 shared pathways including N-Glycan biosynthesis, Various types of N-glycan biosynthesis. OSTC 3 shared pathwaysN-Glycan biosynthesis, Various types of N-glycan biosynthesis, Protein processing in endoplasmic reticulum Related via 3 shared pathways including N-Glycan biosynthesis, Various types of N-glycan biosynthesis.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
MAN1A2	0	[]	5	["N-Glycan biosynthesis","Various types of N-glycan biosynthesis","Protein processing in endoplasmic reticulum","Intra-Golgi traffic","Progressive trimming of alpha-1,2-linked mannose residues from Man9\/8\/7GlcNAc2 to produce Man5GlcNAc2"]	0	[]
MAN1A1	0	[]	5	["N-Glycan biosynthesis","Various types of N-glycan biosynthesis","Protein processing in endoplasmic reticulum","Intra-Golgi traffic","Progressive trimming of alpha-1,2-linked mannose residues from Man9\/8\/7GlcNAc2 to produce Man5GlcNAc2"]	0	[]
KRTCAP2	0	[]	3	["N-Glycan biosynthesis","Various types of N-glycan biosynthesis","Protein processing in endoplasmic reticulum"]	0	[]
STT3B	0	[]	3	["N-Glycan biosynthesis","Various types of N-glycan biosynthesis","Protein processing in endoplasmic reticulum"]	0	[]
OSTC	0	[]	3	["N-Glycan biosynthesis","Various types of N-glycan biosynthesis","Protein processing in endoplasmic reticulum"]	0	[]

Diseases Linked via Similar Genes

Metabolic syndrome Linked via 2 of 5 related genesMAN1A2, MAN1A1 Diabetes mellitus type 2 Linked via 2 of 5 related genesMAN1A2, MAN1A1 Gout Linked via 2 of 5 related genesKRTCAP2, STT3B Insomnia Linked via 1 of 5 related genesMAN1A2 Oligodendroglioma Linked via 1 of 5 related genesMAN1A2

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Metabolic syndrome	2	["MAN1A2","MAN1A1"]
Diabetes mellitus type 2	2	["MAN1A2","MAN1A1"]
Gout	2	["KRTCAP2","STT3B"]
Insomnia	1	["MAN1A2"]
Oligodendroglioma	1	["MAN1A2"]