MAGEB6 (MAGE family member B6)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 158809
• Gene name: MAGE family member B6
• Gene symbol: MAGEB6
• Synonyms (NCBI Gene): CT3.4, MAGE-B6, MAGEB6A
• Chromosome: X
• Chromosome location: Xp21.3
• Summary: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB gen

miRNA Show/Hide all (19)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1125684	hsa-miR-106a	CLIP-seq
MIRT1125685	hsa-miR-106b	CLIP-seq
MIRT1125686	hsa-miR-142-5p	CLIP-seq
MIRT1125687	hsa-miR-17	CLIP-seq
MIRT1125688	hsa-miR-20a	CLIP-seq
MIRT1125689	hsa-miR-20b	CLIP-seq
MIRT1125690	hsa-miR-3609	CLIP-seq
MIRT1125691	hsa-miR-3647-3p	CLIP-seq
MIRT1125692	hsa-miR-4796-3p	CLIP-seq
MIRT1125693	hsa-miR-4803	CLIP-seq
MIRT1125694	hsa-miR-519d	CLIP-seq
MIRT1125695	hsa-miR-548ah	CLIP-seq
MIRT1125696	hsa-miR-93	CLIP-seq
MIRT2266021	hsa-miR-1236	CLIP-seq
MIRT2266022	hsa-miR-1279	CLIP-seq
MIRT2266023	hsa-miR-1537	CLIP-seq
MIRT2266024	hsa-miR-4753-3p	CLIP-seq
MIRT2266025	hsa-miR-4768-5p	CLIP-seq
MIRT2266026	hsa-miR-656	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA
GO:0005515	Function	Protein binding	IPI	23275563, 25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA

Other IDs

• MIM: 300467
• HGNC: 23796
• e!Ensembl: ENSG00000176746

Protein

• UniProt ID: Q8N7X4
• Protein name: Melanoma-associated antigen B6 (Cancer/testis antigen 3.4) (CT3.4) (MAGE-B6 antigen)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01454	MAGE	202 → 370	MAGE family	Family
  PF12440	MAGE_N	5 → 95	Melanoma associated antigen family N terminal	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins. {ECO:0000269|PubMed:10861452}.
• Sequence:

  MPRGHKSKLRTCEKRQETNGQPQGLTGPQATAEKQEESHSSSSSSRACLGDCRRSSDASI
  PQESQGVSPTGSPDAVVSYSKSDVAANGQDEKSPSTSRDASVPQESQGASPTGSPDAGVS
  GSKYDVAANGQDEKSPSTSHDVSVPQESQGASPTGSPDAGVSGSKYDVAAEGEDEESVSA
  SQKAIIFKRLSKDAVKKKACTLAQFLQKKFEKKESILKADMLKCVRREYKPYFPQILNRT
  SQHLVVAFGVELKEMDSSGESYTLVSKLGLPSEGILSGDNALPKSGLLMSLLVVIFMNGN
  CATEEEVWEFLGLLGIYDGILHSIYGDARKIITEDLVQDKYVVYRQVCNSDPPCYEFLWG
  PRAYAETTKMRVLRVLADSSNTSPGLYPHLYEDALIDEVERALRLRA

• Sequence length: 407

Related Genes

No strongly related genes found yet for MAGEB6.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to MAGEB6.