LURAP1 (leucine rich adaptor protein 1)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 541468
• Gene name: Leucine rich adaptor protein 1
• Gene symbol: LURAP1
• Synonyms (NCBI Gene): C1orf190, LRAP35a, LRP35A
• Chromosome: 1
• Chromosome location: 1p34.1

miRNA Show/Hide all (31)

miRTarBase ID	miRNA	Experiments	Reference
MIRT042466	hsa-miR-423-3p	CLASH	23622248
MIRT722283	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT722282	hsa-miR-5088-3p	HITS-CLIP	19536157
MIRT722281	hsa-miR-6734-3p	HITS-CLIP	19536157
MIRT722280	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT722279	hsa-miR-516a-3p	HITS-CLIP	19536157
MIRT722278	hsa-miR-516b-3p	HITS-CLIP	19536157
MIRT722277	hsa-miR-7162-5p	HITS-CLIP	19536157
MIRT722276	hsa-miR-6815-3p	HITS-CLIP	19536157
MIRT722275	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT722274	hsa-miR-623	HITS-CLIP	19536157
MIRT722273	hsa-miR-204-5p	HITS-CLIP	19536157
MIRT722272	hsa-miR-211-5p	HITS-CLIP	19536157
MIRT722271	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT722270	hsa-miR-4755-5p	HITS-CLIP	19536157
MIRT722269	hsa-miR-5006-3p	HITS-CLIP	19536157
MIRT722283	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT722282	hsa-miR-5088-3p	HITS-CLIP	19536157
MIRT722281	hsa-miR-6734-3p	HITS-CLIP	19536157
MIRT722280	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT722279	hsa-miR-516a-3p	HITS-CLIP	19536157
MIRT722278	hsa-miR-516b-3p	HITS-CLIP	19536157
MIRT722277	hsa-miR-7162-5p	HITS-CLIP	19536157
MIRT722276	hsa-miR-6815-3p	HITS-CLIP	19536157
MIRT722275	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT722274	hsa-miR-623	HITS-CLIP	19536157
MIRT722273	hsa-miR-204-5p	HITS-CLIP	19536157
MIRT722272	hsa-miR-211-5p	HITS-CLIP	19536157
MIRT722271	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT722270	hsa-miR-4755-5p	HITS-CLIP	19536157
MIRT722269	hsa-miR-5006-3p	HITS-CLIP	19536157

Gene ontology (GO) Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001819	Process	Positive regulation of cytokine production	IBA
GO:0001819	Process	Positive regulation of cytokine production	IDA	21048106
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 25910212, 31515488, 32296183, 32814053, 33961781
GO:0005737	Component	Cytoplasm	IDA	21048106
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IBA
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	21048106
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IEA

Other IDs

• MIM: 616129
• HGNC: 32327
• e!Ensembl: ENSG00000171357

Protein

• UniProt ID: Q96LR2
• Protein name: Leucine rich adaptor protein 1 (Leucine repeat adapter protein 35A)
• Protein function: Acts as an activator of the canonical NF-kappa-B pathway and drive the production of pro-inflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway (PubMed:21048106).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14854	LURAP	39 → 159	Leucine rich adaptor protein	Family

• Sequence:

  MEGTVESQTPDLRDVEGKVGRKTPEGLLRGLRGECELGTSGALLLPGASSTGHDLGDKIM
  ALKMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPG
  RSRRGSWDSLPDTSTTDRLDSVSIGSFLDTVAPSELDEQGPPGAPRSEMDWAKVIAGGER
  ARTEVDVAATRLGSLRAVWKPPGERLQGGPPESPEDESAKLGFEAHWFWEQCQDDVTFL

• Sequence length: 239

Related Genes

No strongly related genes found yet for LURAP1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to LURAP1.