LRRC70 (leucine rich repeat containing 70)

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Gene Gene information from NCBI Gene database.
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Entrez ID 100130733
Gene name Leucine rich repeat containing 70
Gene symbol LRRC70
Synonyms (NCBI Gene)
SLRN
Chromosome 5
Chromosome location 5q12.1
miRNA miRNA information provided by mirtarbase database.
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miRTarBase ID miRNA Experiments Reference
MIRT017786 hsa-miR-335-5p Microarray 18185580
MIRT2453390 hsa-miR-3173-3p CLIP-seq
MIRT2453391 hsa-miR-410 CLIP-seq
MIRT2453392 hsa-miR-4428 CLIP-seq
MIRT2453393 hsa-miR-944 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane IDA 12767927
GO:0016020 Component Membrane IEA
GO:0060760 Process Positive regulation of response to cytokine stimulus IMP 12767927
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z2Q7
Protein name Leucine-rich repeat-containing protein 70 (Synleurin)
Protein function Renders cells highly sensitive to the activation by cytokines and lipopolysaccharide (LPS).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13855 LRR_8 133 → 192 Leucine rich repeat Repeat
PF13855 LRR_8 228 → 288 Leucine rich repeat Repeat
PF13855 LRR_8 181 → 240 Leucine rich repeat Repeat
PF13855 LRR_8 108 → 168 Leucine rich repeat Repeat
PF13855 LRR_8 160 → 216 Leucine rich repeat Repeat
PF13855 LRR_8 204 → 264 Leucine rich repeat Repeat
PF13855 LRR_8 253 → 312 Leucine rich repeat Repeat
PF13855 LRR_8 300 → 360 Leucine rich repeat Repeat
PF13855 LRR_8 60 → 118 Leucine rich repeat Repeat
Tissue specificity TISSUE SPECIFICITY: Expressed at low levels in many tissues, including smooth muscle, brain, uterus, pancreas, cartilage, adipose, spleen and testis. {ECO:0000269|PubMed:12767927}.
Sequence 
MCGLQFSLPCLRLFLVVTCYLLLLLHKEILGCSSVCQLCTGRQINCRNLGLSSIPKNFPE
STVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFI
KRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMV
ALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPI
EAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLK
NLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNP
WECNCKLLGLRDWLASSAITLNIYCQNPPSMRGRALRYINITNCVTSSINVSRAWAVVKS
PHIHHKTTALMMAWHKVTTNGSPLENTETENITFWERIPTSPAGRFFQENAFGNPLETTA
VLPVQIQLTTSVTLNLEKNSALPNDAASMSGKTSLICTQEVEKLNEAFDILLAFFILACV
LIIFLIYKVVQFKQKLKASENSRENRLEYYSFYQSARYNVTASICNTSPNSLESPGLEQI
RLHKQIVPENEAQVILFEHSAL
Sequence length 622
Interactions View interactions

No strongly related genes found yet for LRRC70.

No additional diseases found yet through genes similar to LRRC70.