LRRC3C (leucine rich repeat containing 3C)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 100505591
• Gene name: Leucine rich repeat containing 3C
• Gene symbol: LRRC3C
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17q21.1

miRNA Show/Hide all (152)

miRTarBase ID	miRNA	Experiments	Reference
MIRT717157	hsa-miR-186-5p	HITS-CLIP	19536157
MIRT717156	hsa-miR-584-3p	HITS-CLIP	19536157
MIRT717155	hsa-miR-4277	HITS-CLIP	19536157
MIRT717154	hsa-miR-6715b-3p	HITS-CLIP	19536157
MIRT717153	hsa-miR-155-3p	HITS-CLIP	19536157
MIRT717152	hsa-miR-30b-5p	HITS-CLIP	19536157
MIRT717151	hsa-miR-30c-5p	HITS-CLIP	19536157
MIRT692180	hsa-miR-7846-3p	HITS-CLIP	23313552
MIRT692179	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT692178	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT692177	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT692176	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT692175	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT692174	hsa-miR-4252	HITS-CLIP	23313552
MIRT692173	hsa-miR-4683	HITS-CLIP	23313552
MIRT692172	hsa-miR-7703	HITS-CLIP	23313552
MIRT662764	hsa-miR-6856-3p	HITS-CLIP	23824327
MIRT662763	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT662762	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT662761	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT662760	hsa-miR-4780	HITS-CLIP	23824327
MIRT662759	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT662758	hsa-miR-5193	HITS-CLIP	23824327
MIRT662757	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT662756	hsa-miR-4287	HITS-CLIP	23824327
MIRT662755	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT662754	hsa-miR-4749-3p	HITS-CLIP	23824327
MIRT662753	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT662752	hsa-miR-623	HITS-CLIP	23824327
MIRT662751	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT662750	hsa-miR-6772-3p	HITS-CLIP	23824327
MIRT662749	hsa-miR-4714-3p	HITS-CLIP	23824327
MIRT662748	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT662747	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT662746	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT662745	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT662744	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT662743	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT662742	hsa-miR-7114-5p	HITS-CLIP	23824327
MIRT662741	hsa-miR-134-3p	HITS-CLIP	23824327
MIRT662740	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT662739	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT662738	hsa-miR-3135b	HITS-CLIP	23824327
MIRT662737	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT662736	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT662735	hsa-miR-3136-3p	HITS-CLIP	23824327
MIRT662734	hsa-miR-7155-3p	HITS-CLIP	23824327
MIRT662733	hsa-miR-3652	HITS-CLIP	23824327
MIRT662732	hsa-miR-4430	HITS-CLIP	23824327
MIRT662731	hsa-miR-5698	HITS-CLIP	23824327
MIRT662730	hsa-miR-3650	HITS-CLIP	23824327
MIRT662729	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT662728	hsa-miR-663b	HITS-CLIP	23824327
MIRT662727	hsa-miR-7641	HITS-CLIP	23824327
MIRT662726	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT662725	hsa-miR-3689d	HITS-CLIP	23824327
MIRT569199	hsa-miR-4524b-3p	PAR-CLIP	20371350
MIRT569198	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT569197	hsa-miR-4459	PAR-CLIP	20371350
MIRT569196	hsa-miR-1253	PAR-CLIP	20371350
MIRT569195	hsa-miR-4419a	PAR-CLIP	20371350
MIRT569194	hsa-miR-4510	PAR-CLIP	20371350
MIRT569193	hsa-miR-6127	PAR-CLIP	20371350
MIRT569192	hsa-miR-6129	PAR-CLIP	20371350
MIRT569191	hsa-miR-6130	PAR-CLIP	20371350
MIRT569190	hsa-miR-6133	PAR-CLIP	20371350
MIRT569189	hsa-miR-658	PAR-CLIP	20371350
MIRT569188	hsa-miR-4434	PAR-CLIP	20371350
MIRT569187	hsa-miR-4516	PAR-CLIP	20371350
MIRT569186	hsa-miR-5703	PAR-CLIP	20371350
MIRT569185	hsa-miR-765	PAR-CLIP	20371350
MIRT569184	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT569182	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT569183	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT569181	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT569180	hsa-miR-4298	PAR-CLIP	20371350
MIRT717157	hsa-miR-186-5p	HITS-CLIP	19536157
MIRT717156	hsa-miR-584-3p	HITS-CLIP	19536157
MIRT717155	hsa-miR-4277	HITS-CLIP	19536157
MIRT717154	hsa-miR-6715b-3p	HITS-CLIP	19536157
MIRT717153	hsa-miR-155-3p	HITS-CLIP	19536157
MIRT717152	hsa-miR-30b-5p	HITS-CLIP	19536157
MIRT717151	hsa-miR-30c-5p	HITS-CLIP	19536157
MIRT692180	hsa-miR-7846-3p	HITS-CLIP	23313552
MIRT692179	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT692178	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT692177	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT692176	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT692175	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT692174	hsa-miR-4252	HITS-CLIP	23313552
MIRT692173	hsa-miR-4683	HITS-CLIP	23313552
MIRT692172	hsa-miR-7703	HITS-CLIP	23313552
MIRT662764	hsa-miR-6856-3p	HITS-CLIP	23824327
MIRT662763	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT662762	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT662761	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT662760	hsa-miR-4780	HITS-CLIP	23824327
MIRT662759	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT662758	hsa-miR-5193	HITS-CLIP	23824327
MIRT662757	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT662756	hsa-miR-4287	HITS-CLIP	23824327
MIRT662755	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT662754	hsa-miR-4749-3p	HITS-CLIP	23824327
MIRT662753	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT662752	hsa-miR-623	HITS-CLIP	23824327
MIRT662751	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT662750	hsa-miR-6772-3p	HITS-CLIP	23824327
MIRT662749	hsa-miR-4714-3p	HITS-CLIP	23824327
MIRT662748	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT662747	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT662746	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT662745	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT662744	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT662743	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT662742	hsa-miR-7114-5p	HITS-CLIP	23824327
MIRT662741	hsa-miR-134-3p	HITS-CLIP	23824327
MIRT662740	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT662739	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT662738	hsa-miR-3135b	HITS-CLIP	23824327
MIRT662737	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT662736	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT662735	hsa-miR-3136-3p	HITS-CLIP	23824327
MIRT662734	hsa-miR-7155-3p	HITS-CLIP	23824327
MIRT662733	hsa-miR-3652	HITS-CLIP	23824327
MIRT662732	hsa-miR-4430	HITS-CLIP	23824327
MIRT662731	hsa-miR-5698	HITS-CLIP	23824327
MIRT662730	hsa-miR-3650	HITS-CLIP	23824327
MIRT662729	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT662728	hsa-miR-663b	HITS-CLIP	23824327
MIRT662727	hsa-miR-7641	HITS-CLIP	23824327
MIRT662726	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT662725	hsa-miR-3689d	HITS-CLIP	23824327
MIRT569199	hsa-miR-4524b-3p	PAR-CLIP	20371350
MIRT569198	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT569197	hsa-miR-4459	PAR-CLIP	20371350
MIRT569196	hsa-miR-1253	PAR-CLIP	20371350
MIRT569195	hsa-miR-4419a	PAR-CLIP	20371350
MIRT569194	hsa-miR-4510	PAR-CLIP	20371350
MIRT569193	hsa-miR-6127	PAR-CLIP	20371350
MIRT569192	hsa-miR-6129	PAR-CLIP	20371350
MIRT569191	hsa-miR-6130	PAR-CLIP	20371350
MIRT569190	hsa-miR-6133	PAR-CLIP	20371350
MIRT569189	hsa-miR-658	PAR-CLIP	20371350
MIRT569188	hsa-miR-4434	PAR-CLIP	20371350
MIRT569187	hsa-miR-4516	PAR-CLIP	20371350
MIRT569186	hsa-miR-5703	PAR-CLIP	20371350
MIRT569185	hsa-miR-765	PAR-CLIP	20371350
MIRT569184	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT569182	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT569183	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT569181	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT569180	hsa-miR-4298	PAR-CLIP	20371350

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005886	Component	Plasma membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0038023	Function	Signaling receptor activity	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: A6NJW4
• Protein name: Leucine-rich repeat-containing protein 3C
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13855	LRR_8	80 → 140	Leucine rich repeat	Repeat

• Sequence:

  MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
  RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
  AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
  TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
  VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV

• Sequence length: 275

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (7)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
ASTHMA	—	GWAS catalog	21150878, 22561531, 31669095, 35126453	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	GWAS catalog	31043756	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR I DISORDER	—	GWAS catalog	31043756	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	35126453	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHILDHOOD ONSET ASTHMA	—	GWAS catalog	31669095	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	39792054	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	34594039	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Childhood asthma	Asthma	GWASDB_DG	17611496		★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn Disease	BEFREE	26484354		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	26484354		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	26484354	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for LRRC3C.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to LRRC3C.