Log in to bookmark this gene

Bookmark This Gene

Gene Gene information from NCBI Gene database.
Entrez ID 10162
Gene name Lysophosphatidylcholine acyltransferase 3
Gene symbol LPCAT3
Synonyms (NCBI Gene)
C3FLPCATLPLAT 5LPLAT12LPSATMBOAT5OACT5nessy
Chromosome 12
Chromosome location 12p13.31
miRNA miRNA information provided by mirtarbase database.
319 Show/Hide all (319)
miRTarBase ID miRNA Experiments Reference
MIRT027464 hsa-miR-98-5p Microarray 19088304
MIRT032237 hsa-let-7b-5p Proteomics 18668040
MIRT649795 hsa-miR-561-3p HITS-CLIP 23824327
MIRT649794 hsa-miR-3613-3p HITS-CLIP 23824327
MIRT649793 hsa-miR-3127-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
59 Show/Hide all (59)
GO ID Ontology Definition Evidence Reference
GO:0003841 Function 1-acylglycerol-3-phosphate O-acyltransferase activity TAS
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IDA 18195019
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0005789 Component Endoplasmic reticulum membrane TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611950 30244 ENSG00000111684
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6P1A2
Protein name Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysoph
Protein function Lysophospholipid O-acyltransferase (LPLAT) that catalyzes the reacylation step of the phospholipid remodeling process also known as the Lands cycle (PubMed:18195019, PubMed:18772128, PubMed:18782225). Catalyzes transfer of the fatty acyl chain f
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03062 MBOAT 126 → 437 MBOAT, membrane-bound O-acyltransferase family Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in liver, pancreas and adipose tissue. Very low expression in skeletal muscle and heart. Detected in neutrophils. {ECO:0000269|PubMed:18195019, ECO:0000269|PubMed:18772128}.
Sequence
Sequence length 487
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Glycerophospholipid metabolism Acyl chain remodelling of PC
Ferroptosis Acyl chain remodelling of PS
  Acyl chain remodelling of PE