LDOC1 (LDOC1 regulator of NFKB signaling)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 23641
• Gene name: LDOC1 regulator of NFKB signaling
• Gene symbol: LDOC1
• Synonyms (NCBI Gene): BCUR1, Mar7, Mart7, RTL7, SIRH7
• Chromosome: X
• Chromosome location: Xq27.1
• Summary: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought t

miRNA Show/Hide all (317)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002351	kshv-miR-K12-11-3p	Luciferase reporter assay	17881434
MIRT001805	hsa-miR-155-5p	Luciferase reporter assay	17881434
MIRT001805	hsa-miR-155-5p	Reporter assay;Other	17881434
MIRT488323	hsa-miR-3936	PAR-CLIP	23592263
MIRT488322	hsa-miR-2278	PAR-CLIP	23592263
MIRT488321	hsa-miR-4519	PAR-CLIP	23592263
MIRT488320	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT488319	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT488318	hsa-miR-5693	PAR-CLIP	23592263
MIRT488317	hsa-miR-221-5p	PAR-CLIP	23592263
MIRT488316	hsa-miR-8073	PAR-CLIP	23592263
MIRT488315	hsa-miR-3616-3p	PAR-CLIP	23592263
MIRT488314	hsa-miR-6809-5p	PAR-CLIP	23592263
MIRT488313	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT488312	hsa-miR-8085	PAR-CLIP	23592263
MIRT488310	hsa-miR-3144-5p	PAR-CLIP	23592263
MIRT488311	hsa-miR-3175	PAR-CLIP	23592263
MIRT488309	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT488308	hsa-miR-5698	PAR-CLIP	23592263
MIRT488307	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT488306	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT488323	hsa-miR-3936	PAR-CLIP	23592263
MIRT488322	hsa-miR-2278	PAR-CLIP	23592263
MIRT488321	hsa-miR-4519	PAR-CLIP	23592263
MIRT488320	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT488319	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT488318	hsa-miR-5693	PAR-CLIP	23592263
MIRT488317	hsa-miR-221-5p	PAR-CLIP	23592263
MIRT488316	hsa-miR-8073	PAR-CLIP	23592263
MIRT488315	hsa-miR-3616-3p	PAR-CLIP	23592263
MIRT488314	hsa-miR-6809-5p	PAR-CLIP	23592263
MIRT488313	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT488312	hsa-miR-8085	PAR-CLIP	23592263
MIRT488310	hsa-miR-3144-5p	PAR-CLIP	23592263
MIRT488311	hsa-miR-3175	PAR-CLIP	23592263
MIRT488309	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT488308	hsa-miR-5698	PAR-CLIP	23592263
MIRT488307	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT488306	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT1106919	hsa-miR-103a	CLIP-seq
MIRT1106920	hsa-miR-105	CLIP-seq
MIRT1106921	hsa-miR-107	CLIP-seq
MIRT1106922	hsa-miR-1184	CLIP-seq
MIRT1106923	hsa-miR-1197	CLIP-seq
MIRT1106924	hsa-miR-1207-5p	CLIP-seq
MIRT1106925	hsa-miR-1224-5p	CLIP-seq
MIRT1106926	hsa-miR-1273e	CLIP-seq
MIRT1106927	hsa-miR-1288	CLIP-seq
MIRT1106928	hsa-miR-1343	CLIP-seq
MIRT1106929	hsa-miR-1587	CLIP-seq
MIRT1106930	hsa-miR-15a	CLIP-seq
MIRT1106931	hsa-miR-15b	CLIP-seq
MIRT1106932	hsa-miR-16	CLIP-seq
MIRT1106933	hsa-miR-1908	CLIP-seq
MIRT1106934	hsa-miR-1909	CLIP-seq
MIRT1106935	hsa-miR-195	CLIP-seq
MIRT1106936	hsa-miR-196a	CLIP-seq
MIRT1106937	hsa-miR-196b	CLIP-seq
MIRT1106938	hsa-miR-2052	CLIP-seq
MIRT1106939	hsa-miR-2117	CLIP-seq
MIRT1106940	hsa-miR-214	CLIP-seq
MIRT1106941	hsa-miR-2277-5p	CLIP-seq
MIRT1106942	hsa-miR-2355-3p	CLIP-seq
MIRT1106943	hsa-miR-28-5p	CLIP-seq
MIRT1106944	hsa-miR-2861	CLIP-seq
MIRT1106945	hsa-miR-3115	CLIP-seq
MIRT1106946	hsa-miR-3139	CLIP-seq
MIRT1106947	hsa-miR-3140-3p	CLIP-seq
MIRT1106948	hsa-miR-3145-3p	CLIP-seq
MIRT1106949	hsa-miR-3150b-3p	CLIP-seq
MIRT1106950	hsa-miR-3151	CLIP-seq
MIRT1106951	hsa-miR-3160-3p	CLIP-seq
MIRT1106952	hsa-miR-3168	CLIP-seq
MIRT1106953	hsa-miR-3170	CLIP-seq
MIRT1106954	hsa-miR-3178	CLIP-seq
MIRT1106955	hsa-miR-3180-5p	CLIP-seq
MIRT1106956	hsa-miR-3192	CLIP-seq
MIRT1106957	hsa-miR-3199	CLIP-seq
MIRT1106958	hsa-miR-326	CLIP-seq
MIRT1106959	hsa-miR-330-5p	CLIP-seq
MIRT1106960	hsa-miR-3611	CLIP-seq
MIRT1106961	hsa-miR-3616-5p	CLIP-seq
MIRT1106962	hsa-miR-3619-5p	CLIP-seq
MIRT1106963	hsa-miR-3646	CLIP-seq
MIRT1106964	hsa-miR-3647-3p	CLIP-seq
MIRT1106965	hsa-miR-3647-5p	CLIP-seq
MIRT1106966	hsa-miR-365	CLIP-seq
MIRT1106967	hsa-miR-3665	CLIP-seq
MIRT1106968	hsa-miR-3681	CLIP-seq
MIRT1106969	hsa-miR-3690	CLIP-seq
MIRT1106970	hsa-miR-3691-5p	CLIP-seq
MIRT1106971	hsa-miR-378g	CLIP-seq
MIRT1106972	hsa-miR-3915	CLIP-seq
MIRT1106973	hsa-miR-3926	CLIP-seq
MIRT1106974	hsa-miR-3927	CLIP-seq
MIRT1106975	hsa-miR-3942-3p	CLIP-seq
MIRT1106976	hsa-miR-424	CLIP-seq
MIRT1106977	hsa-miR-4254	CLIP-seq
MIRT1106978	hsa-miR-4269	CLIP-seq
MIRT1106979	hsa-miR-4299	CLIP-seq
MIRT1106980	hsa-miR-4314	CLIP-seq
MIRT1106981	hsa-miR-4436a	CLIP-seq
MIRT1106982	hsa-miR-4436b-3p	CLIP-seq
MIRT1106983	hsa-miR-4456	CLIP-seq
MIRT1106984	hsa-miR-4461	CLIP-seq
MIRT1106985	hsa-miR-4468	CLIP-seq
MIRT1106986	hsa-miR-4481	CLIP-seq
MIRT1106987	hsa-miR-4487	CLIP-seq
MIRT1106988	hsa-miR-4492	CLIP-seq
MIRT1106989	hsa-miR-4498	CLIP-seq
MIRT1106990	hsa-miR-4524	CLIP-seq
MIRT1106991	hsa-miR-4532	CLIP-seq
MIRT1106992	hsa-miR-4645-5p	CLIP-seq
MIRT1106993	hsa-miR-4646-3p	CLIP-seq
MIRT1106994	hsa-miR-4646-5p	CLIP-seq
MIRT1106995	hsa-miR-4648	CLIP-seq
MIRT1106996	hsa-miR-4654	CLIP-seq
MIRT1106997	hsa-miR-4656	CLIP-seq
MIRT1106998	hsa-miR-4673	CLIP-seq
MIRT1106999	hsa-miR-4675	CLIP-seq
MIRT1107000	hsa-miR-4689	CLIP-seq
MIRT1107001	hsa-miR-4690-5p	CLIP-seq
MIRT1107002	hsa-miR-4709-3p	CLIP-seq
MIRT1107003	hsa-miR-4710	CLIP-seq
MIRT1107004	hsa-miR-4713-3p	CLIP-seq
MIRT1107005	hsa-miR-4728-5p	CLIP-seq
MIRT1107006	hsa-miR-4731-5p	CLIP-seq
MIRT1107007	hsa-miR-4736	CLIP-seq
MIRT1107008	hsa-miR-4741	CLIP-seq
MIRT1107009	hsa-miR-4745-5p	CLIP-seq
MIRT1107010	hsa-miR-4747-5p	CLIP-seq
MIRT1107011	hsa-miR-4755-3p	CLIP-seq
MIRT1107012	hsa-miR-4758-5p	CLIP-seq
MIRT1107013	hsa-miR-4763-3p	CLIP-seq
MIRT1107014	hsa-miR-4764-5p	CLIP-seq
MIRT1107015	hsa-miR-4769-5p	CLIP-seq
MIRT1107016	hsa-miR-4784	CLIP-seq
MIRT1107017	hsa-miR-4792	CLIP-seq
MIRT1107018	hsa-miR-4795-5p	CLIP-seq
MIRT1107019	hsa-miR-483-5p	CLIP-seq
MIRT1107020	hsa-miR-486-3p	CLIP-seq
MIRT1107021	hsa-miR-497	CLIP-seq
MIRT1107022	hsa-miR-520f	CLIP-seq
MIRT1107023	hsa-miR-539	CLIP-seq
MIRT1107024	hsa-miR-541	CLIP-seq
MIRT1107025	hsa-miR-548q	CLIP-seq
MIRT1107026	hsa-miR-548s	CLIP-seq
MIRT1107027	hsa-miR-558	CLIP-seq
MIRT1107028	hsa-miR-573	CLIP-seq
MIRT1107029	hsa-miR-636	CLIP-seq
MIRT1107030	hsa-miR-654-5p	CLIP-seq
MIRT1107031	hsa-miR-663	CLIP-seq
MIRT1107032	hsa-miR-708	CLIP-seq
MIRT1107033	hsa-miR-761	CLIP-seq
MIRT1107034	hsa-miR-762	CLIP-seq
MIRT1107035	hsa-miR-885-3p	CLIP-seq
MIRT2029480	hsa-miR-103b	CLIP-seq
MIRT1106923	hsa-miR-1197	CLIP-seq
MIRT2029481	hsa-miR-1256	CLIP-seq
MIRT1106930	hsa-miR-15a	CLIP-seq
MIRT1106931	hsa-miR-15b	CLIP-seq
MIRT1106932	hsa-miR-16	CLIP-seq
MIRT1106934	hsa-miR-1909	CLIP-seq
MIRT2029482	hsa-miR-194	CLIP-seq
MIRT1106935	hsa-miR-195	CLIP-seq
MIRT1106936	hsa-miR-196a	CLIP-seq
MIRT1106937	hsa-miR-196b	CLIP-seq
MIRT1106940	hsa-miR-214	CLIP-seq
MIRT1106944	hsa-miR-2861	CLIP-seq
MIRT2029483	hsa-miR-3127-3p	CLIP-seq
MIRT2029484	hsa-miR-3127-5p	CLIP-seq
MIRT1106947	hsa-miR-3140-3p	CLIP-seq
MIRT1106953	hsa-miR-3170	CLIP-seq
MIRT1106955	hsa-miR-3180-5p	CLIP-seq
MIRT1106962	hsa-miR-3619-5p	CLIP-seq
MIRT1106966	hsa-miR-365	CLIP-seq
MIRT2029485	hsa-miR-3662	CLIP-seq
MIRT2029486	hsa-miR-3910	CLIP-seq
MIRT1106973	hsa-miR-3926	CLIP-seq
MIRT2029487	hsa-miR-3929	CLIP-seq
MIRT1106975	hsa-miR-3942-3p	CLIP-seq
MIRT1106976	hsa-miR-424	CLIP-seq
MIRT1106978	hsa-miR-4269	CLIP-seq
MIRT2029488	hsa-miR-4419b	CLIP-seq
MIRT1106981	hsa-miR-4436a	CLIP-seq
MIRT2029489	hsa-miR-4478	CLIP-seq
MIRT2029490	hsa-miR-4485	CLIP-seq
MIRT1106990	hsa-miR-4524	CLIP-seq
MIRT1106991	hsa-miR-4532	CLIP-seq
MIRT1106992	hsa-miR-4645-5p	CLIP-seq
MIRT1106998	hsa-miR-4673	CLIP-seq
MIRT1107001	hsa-miR-4690-5p	CLIP-seq
MIRT1107004	hsa-miR-4713-3p	CLIP-seq
MIRT1107005	hsa-miR-4728-5p	CLIP-seq
MIRT1107006	hsa-miR-4731-5p	CLIP-seq
MIRT2029491	hsa-miR-4766-5p	CLIP-seq
MIRT2029492	hsa-miR-488	CLIP-seq
MIRT1107021	hsa-miR-497	CLIP-seq
MIRT2029493	hsa-miR-542-5p	CLIP-seq
MIRT2029494	hsa-miR-548an	CLIP-seq
MIRT1107026	hsa-miR-548s	CLIP-seq
MIRT2029495	hsa-miR-604	CLIP-seq
MIRT2029496	hsa-miR-654-3p	CLIP-seq
MIRT1107033	hsa-miR-761	CLIP-seq
MIRT2029497	hsa-miR-887	CLIP-seq
MIRT1106923	hsa-miR-1197	CLIP-seq
MIRT2029481	hsa-miR-1256	CLIP-seq
MIRT1106930	hsa-miR-15a	CLIP-seq
MIRT1106931	hsa-miR-15b	CLIP-seq
MIRT1106932	hsa-miR-16	CLIP-seq
MIRT1106934	hsa-miR-1909	CLIP-seq
MIRT2029482	hsa-miR-194	CLIP-seq
MIRT1106935	hsa-miR-195	CLIP-seq
MIRT1106940	hsa-miR-214	CLIP-seq
MIRT2260417	hsa-miR-2467-5p	CLIP-seq
MIRT1106944	hsa-miR-2861	CLIP-seq
MIRT2260418	hsa-miR-3132	CLIP-seq
MIRT1106953	hsa-miR-3170	CLIP-seq
MIRT1106955	hsa-miR-3180-5p	CLIP-seq
MIRT1106962	hsa-miR-3619-5p	CLIP-seq
MIRT1106973	hsa-miR-3926	CLIP-seq
MIRT1106975	hsa-miR-3942-3p	CLIP-seq
MIRT1106976	hsa-miR-424	CLIP-seq
MIRT2260419	hsa-miR-425	CLIP-seq
MIRT1106978	hsa-miR-4269	CLIP-seq
MIRT2260420	hsa-miR-4435	CLIP-seq
MIRT1106981	hsa-miR-4436a	CLIP-seq
MIRT1106990	hsa-miR-4524	CLIP-seq
MIRT2260421	hsa-miR-4530	CLIP-seq
MIRT1106991	hsa-miR-4532	CLIP-seq
MIRT1106992	hsa-miR-4645-5p	CLIP-seq
MIRT1106998	hsa-miR-4673	CLIP-seq
MIRT1107001	hsa-miR-4690-5p	CLIP-seq
MIRT1107004	hsa-miR-4713-3p	CLIP-seq
MIRT2260422	hsa-miR-4720-5p	CLIP-seq
MIRT1107005	hsa-miR-4728-5p	CLIP-seq
MIRT1107006	hsa-miR-4731-5p	CLIP-seq
MIRT1107011	hsa-miR-4755-3p	CLIP-seq
MIRT2260423	hsa-miR-4799-3p	CLIP-seq
MIRT1107021	hsa-miR-497	CLIP-seq
MIRT2029493	hsa-miR-542-5p	CLIP-seq
MIRT1107026	hsa-miR-548s	CLIP-seq
MIRT2260424	hsa-miR-582-3p	CLIP-seq
MIRT2029495	hsa-miR-604	CLIP-seq
MIRT2260425	hsa-miR-647	CLIP-seq
MIRT1107033	hsa-miR-761	CLIP-seq
MIRT2260426	hsa-miR-766	CLIP-seq
MIRT1106968	hsa-miR-3681	CLIP-seq
MIRT1106970	hsa-miR-3691-5p	CLIP-seq
MIRT1106986	hsa-miR-4481	CLIP-seq
MIRT1106996	hsa-miR-4654	CLIP-seq
MIRT1107003	hsa-miR-4710	CLIP-seq
MIRT1107009	hsa-miR-4745-5p	CLIP-seq
MIRT1107012	hsa-miR-4758-5p	CLIP-seq
MIRT1107014	hsa-miR-4764-5p	CLIP-seq
MIRT1107015	hsa-miR-4769-5p	CLIP-seq
MIRT1107017	hsa-miR-4792	CLIP-seq
MIRT1106928	hsa-miR-1343	CLIP-seq
MIRT2560464	hsa-miR-148a	CLIP-seq
MIRT2560465	hsa-miR-148b	CLIP-seq
MIRT2560466	hsa-miR-152	CLIP-seq
MIRT2560467	hsa-miR-153	CLIP-seq
MIRT1106930	hsa-miR-15a	CLIP-seq
MIRT1106931	hsa-miR-15b	CLIP-seq
MIRT1106932	hsa-miR-16	CLIP-seq
MIRT2560468	hsa-miR-1825	CLIP-seq
MIRT1106935	hsa-miR-195	CLIP-seq
MIRT1106940	hsa-miR-214	CLIP-seq
MIRT2560469	hsa-miR-2277-3p	CLIP-seq
MIRT1106941	hsa-miR-2277-5p	CLIP-seq
MIRT2260417	hsa-miR-2467-5p	CLIP-seq
MIRT2560470	hsa-miR-3117-5p	CLIP-seq
MIRT2560471	hsa-miR-3148	CLIP-seq
MIRT2560472	hsa-miR-3174	CLIP-seq
MIRT1106954	hsa-miR-3178	CLIP-seq
MIRT2560473	hsa-miR-3188	CLIP-seq
MIRT1106962	hsa-miR-3619-5p	CLIP-seq
MIRT1106963	hsa-miR-3646	CLIP-seq
MIRT1106969	hsa-miR-3690	CLIP-seq
MIRT2560474	hsa-miR-3975	CLIP-seq
MIRT1106976	hsa-miR-424	CLIP-seq
MIRT1106977	hsa-miR-4254	CLIP-seq
MIRT1106985	hsa-miR-4468	CLIP-seq
MIRT2560475	hsa-miR-4496	CLIP-seq
MIRT2260421	hsa-miR-4530	CLIP-seq
MIRT1107002	hsa-miR-4709-3p	CLIP-seq
MIRT1107019	hsa-miR-483-5p	CLIP-seq
MIRT2560476	hsa-miR-485-5p	CLIP-seq
MIRT1107021	hsa-miR-497	CLIP-seq
MIRT1107023	hsa-miR-539	CLIP-seq
MIRT2560477	hsa-miR-548aa	CLIP-seq
MIRT2260424	hsa-miR-582-3p	CLIP-seq
MIRT1107033	hsa-miR-761	CLIP-seq
MIRT2260426	hsa-miR-766	CLIP-seq
MIRT1106928	hsa-miR-1343	CLIP-seq
MIRT1106930	hsa-miR-15a	CLIP-seq
MIRT1106931	hsa-miR-15b	CLIP-seq
MIRT1106932	hsa-miR-16	CLIP-seq
MIRT1106935	hsa-miR-195	CLIP-seq
MIRT1106940	hsa-miR-214	CLIP-seq
MIRT2260417	hsa-miR-2467-5p	CLIP-seq
MIRT2560473	hsa-miR-3188	CLIP-seq
MIRT1106962	hsa-miR-3619-5p	CLIP-seq
MIRT1106963	hsa-miR-3646	CLIP-seq
MIRT1106969	hsa-miR-3690	CLIP-seq
MIRT2560474	hsa-miR-3975	CLIP-seq
MIRT1106976	hsa-miR-424	CLIP-seq
MIRT1106977	hsa-miR-4254	CLIP-seq
MIRT1106985	hsa-miR-4468	CLIP-seq
MIRT2260421	hsa-miR-4530	CLIP-seq
MIRT1107002	hsa-miR-4709-3p	CLIP-seq
MIRT2560476	hsa-miR-485-5p	CLIP-seq
MIRT1107021	hsa-miR-497	CLIP-seq
MIRT1107023	hsa-miR-539	CLIP-seq
MIRT2260424	hsa-miR-582-3p	CLIP-seq
MIRT1107033	hsa-miR-761	CLIP-seq
MIRT2260426	hsa-miR-766	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001893	Process	Maternal placenta development	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 17500595, 19060904, 25416956, 25910212, 26871637, 27812135, 28514442, 29892012, 31515488, 32296183, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	10403563
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	10403563
GO:0060137	Process	Maternal process involved in parturition	IEA
GO:0071222	Process	Cellular response to lipopolysaccharide	IMP	27812135
GO:0071225	Process	Cellular response to muramyl dipeptide	IMP	27812135

Other IDs

• MIM: 300402
• HGNC: 6548
• e!Ensembl: ENSG00000182195

Protein

• UniProt ID: O95751
• Protein name: Protein LDOC1 (Leucine zipper protein down-regulated in cancer cells)
• Protein function: May have an important role in the development and/or progression of some cancers.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF16297	DUF4939	24 → 138	Domain of unknown function (DUF4939)	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed with high levels in brain ant thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined. {ECO:0000269|PubMed:10403563}.
• Sequence:

  MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGE
  SSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRA
  FLDEMKQCFGWDDDEDDDDEEEEDDY

• Sequence length: 146

Related Genes

No strongly related genes found yet for LDOC1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to LDOC1.