Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	160287
Gene name	Lactate dehydrogenase A like 6A
Gene symbol	LDHAL6A
Synonyms (NCBI Gene)	LDH6A
Chromosome	11
Chromosome location	11p15.1

115 Show/Hide all (115)

miRTarBase ID	miRNA	Experiments	Reference
MIRT551816	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707552	hsa-miR-6817-3p	HITS-CLIP	21572407
MIRT551815	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT551814	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT551813	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT551812	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT551811	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT551816	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT551815	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT551814	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT551813	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT551812	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT551811	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT551816	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707552	hsa-miR-6817-3p	HITS-CLIP	21572407
MIRT551815	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT551814	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT551813	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT551812	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT551811	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT551816	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT551815	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT551814	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT551813	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT551812	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT551811	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT1106359	hsa-miR-1227	CLIP-seq
MIRT1106360	hsa-miR-1262	CLIP-seq
MIRT1106361	hsa-miR-128	CLIP-seq
MIRT1106362	hsa-miR-216a	CLIP-seq
MIRT1106363	hsa-miR-216b	CLIP-seq
MIRT1106364	hsa-miR-219-5p	CLIP-seq
MIRT1106365	hsa-miR-24	CLIP-seq
MIRT1106366	hsa-miR-4252	CLIP-seq
MIRT1106367	hsa-miR-4269	CLIP-seq
MIRT1106368	hsa-miR-4284	CLIP-seq
MIRT1106369	hsa-miR-4445	CLIP-seq
MIRT1106370	hsa-miR-4701-3p	CLIP-seq
MIRT1106371	hsa-miR-4782-3p	CLIP-seq
MIRT1106372	hsa-miR-4793-3p	CLIP-seq
MIRT1106373	hsa-miR-508-3p	CLIP-seq
MIRT1106374	hsa-miR-508-5p	CLIP-seq
MIRT1106375	hsa-miR-542-3p	CLIP-seq
MIRT1106376	hsa-miR-661	CLIP-seq
MIRT1106377	hsa-miR-766	CLIP-seq
MIRT1106361	hsa-miR-128	CLIP-seq
MIRT1106362	hsa-miR-216a	CLIP-seq
MIRT1106363	hsa-miR-216b	CLIP-seq
MIRT1106365	hsa-miR-24	CLIP-seq
MIRT1106378	hsa-miR-2682	CLIP-seq
MIRT1106379	hsa-miR-3612	CLIP-seq
MIRT1106380	hsa-miR-3622b-5p	CLIP-seq
MIRT1106367	hsa-miR-4269	CLIP-seq
MIRT1106368	hsa-miR-4284	CLIP-seq
MIRT1106381	hsa-miR-4423-3p	CLIP-seq
MIRT1106382	hsa-miR-4443	CLIP-seq
MIRT1106383	hsa-miR-449c	CLIP-seq
MIRT1106384	hsa-miR-4645-5p	CLIP-seq
MIRT1106385	hsa-miR-4673	CLIP-seq
MIRT1106386	hsa-miR-4753-5p	CLIP-seq
MIRT1106387	hsa-miR-4755-3p	CLIP-seq
MIRT1106388	hsa-miR-4802-5p	CLIP-seq
MIRT1106389	hsa-miR-650	CLIP-seq
MIRT1106390	hsa-miR-940	CLIP-seq
MIRT1106359	hsa-miR-1227	CLIP-seq
MIRT1106360	hsa-miR-1262	CLIP-seq
MIRT1106364	hsa-miR-219-5p	CLIP-seq
MIRT2029425	hsa-miR-331-5p	CLIP-seq
MIRT2029426	hsa-miR-3646	CLIP-seq
MIRT1106366	hsa-miR-4252	CLIP-seq
MIRT1106369	hsa-miR-4445	CLIP-seq
MIRT2029427	hsa-miR-4477a	CLIP-seq
MIRT2029428	hsa-miR-4678	CLIP-seq
MIRT1106370	hsa-miR-4701-3p	CLIP-seq
MIRT1106371	hsa-miR-4782-3p	CLIP-seq
MIRT1106372	hsa-miR-4793-3p	CLIP-seq
MIRT1106373	hsa-miR-508-3p	CLIP-seq
MIRT1106374	hsa-miR-508-5p	CLIP-seq
MIRT1106375	hsa-miR-542-3p	CLIP-seq
MIRT1106376	hsa-miR-661	CLIP-seq
MIRT1106377	hsa-miR-766	CLIP-seq
MIRT1106359	hsa-miR-1227	CLIP-seq
MIRT1106360	hsa-miR-1262	CLIP-seq
MIRT2260267	hsa-miR-1323	CLIP-seq
MIRT1106362	hsa-miR-216a	CLIP-seq
MIRT1106363	hsa-miR-216b	CLIP-seq
MIRT1106364	hsa-miR-219-5p	CLIP-seq
MIRT2260268	hsa-miR-3065-3p	CLIP-seq
MIRT2260269	hsa-miR-3122	CLIP-seq
MIRT2029425	hsa-miR-331-5p	CLIP-seq
MIRT2029426	hsa-miR-3646	CLIP-seq
MIRT2260270	hsa-miR-3689a-3p	CLIP-seq
MIRT2260271	hsa-miR-3689c	CLIP-seq
MIRT2260272	hsa-miR-3913-5p	CLIP-seq
MIRT1106366	hsa-miR-4252	CLIP-seq
MIRT1106369	hsa-miR-4445	CLIP-seq
MIRT2029427	hsa-miR-4477a	CLIP-seq
MIRT2029428	hsa-miR-4678	CLIP-seq
MIRT1106370	hsa-miR-4701-3p	CLIP-seq
MIRT1106371	hsa-miR-4782-3p	CLIP-seq
MIRT1106372	hsa-miR-4793-3p	CLIP-seq
MIRT1106373	hsa-miR-508-3p	CLIP-seq
MIRT1106374	hsa-miR-508-5p	CLIP-seq
MIRT1106375	hsa-miR-542-3p	CLIP-seq
MIRT2260273	hsa-miR-548aa	CLIP-seq
MIRT2260274	hsa-miR-548o	CLIP-seq
MIRT1106376	hsa-miR-661	CLIP-seq
MIRT1106377	hsa-miR-766	CLIP-seq
MIRT2390080	hsa-miR-4761-5p	CLIP-seq
MIRT2452902	hsa-miR-1283	CLIP-seq
MIRT2452903	hsa-miR-3675-3p	CLIP-seq
MIRT2452904	hsa-miR-4684-5p	CLIP-seq
MIRT2452902	hsa-miR-1283	CLIP-seq
MIRT2452903	hsa-miR-3675-3p	CLIP-seq
MIRT2452904	hsa-miR-4684-5p	CLIP-seq

13 Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003824	Function	Catalytic activity	IEA
GO:0004459	Function	L-lactate dehydrogenase (NAD+) activity	IBA
GO:0004459	Function	L-lactate dehydrogenase (NAD+) activity	IDA	18351441
GO:0004459	Function	L-lactate dehydrogenase (NAD+) activity	IEA
GO:0005737	Component	Cytoplasm	IDA	18351441
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IBA
GO:0006089	Process	Lactate metabolic process	IBA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016616	Function	Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
GO:0019752	Process	Carboxylic acid metabolic process	IEA
GO:0042867	Process	Pyruvate catabolic process	IBA
GO:0070062	Component	Extracellular exosome	HDA	23533145

MIM	HGNC	e!Ensembl
618928	28335	ENSG00000166800

Q6ZMR3

Protein name

L-lactate dehydrogenase A-like 6A (LDHA-like protein 6A) (EC 1.1.1.27)

Protein function

Catalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme (PubMed:18351441). Significantly increases the transcriptional activity of JUN, when overexpressed. {ECO:0000269|PubMed:18351441}

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00056	Ldh_1_N	21 → 160	lactate/malate dehydrogenase, NAD binding domain	Family
PF02866	Ldh_1_C	163 → 331	lactate/malate dehydrogenase, alpha/beta C-terminal domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Testis-specific. {ECO:0000269|PubMed:18351441}.

Sequence

MATIKSELIKNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKG
ETMDLQHGSPFMKMPNIVSSKDYLVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKLM
IPNITQYSPHCKLLIVTNPVDILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGI
HSESCHGLILGEHGDSSVPVWSGVNIAGVPLKDLNPDIGTDKDPEQWENVHKKVISSGYE
MVKMKGYTSWGISLSVADLTESILKNLRRVHPVSTLSKGLYGINEDIFLSVPCILGENGI
TDLIKVKLTLEEEACLQKSAETLWEIQKELKL

Sequence length

332

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Glycolysis / Gluconeogenesis	Pyruvate metabolism
Cysteine and methionine metabolism
Pyruvate metabolism
Propanoate metabolism
Metabolic pathways
HIF-1 signaling pathway
Glucagon signaling pathway
Central carbon metabolism in cancer

LDHAL6A (lactate dehydrogenase A like 6A)

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