LBX2 (ladybird homeobox 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 85474
• Gene name: Ladybird homeobox 2
• Gene symbol: LBX2
• Synonyms (NCBI Gene): LP3727
• Chromosome: 2
• Chromosome location: 2p13.1

miRNA Show/Hide all (34)

miRTarBase ID	miRNA	Experiments	Reference
MIRT045973	hsa-miR-125b-5p	CLASH	23622248
MIRT045720	hsa-miR-125a-5p	CLASH	23622248
MIRT042739	hsa-miR-339-5p	CLASH	23622248
MIRT036822	hsa-miR-877-3p	CLASH	23622248
MIRT1105503	hsa-miR-1225-3p	CLIP-seq
MIRT1105504	hsa-miR-1233	CLIP-seq
MIRT1105505	hsa-miR-1304	CLIP-seq
MIRT1105506	hsa-miR-1827	CLIP-seq
MIRT1105507	hsa-miR-4459	CLIP-seq
MIRT1105508	hsa-miR-4722-5p	CLIP-seq
MIRT1105509	hsa-miR-665	CLIP-seq
MIRT1105510	hsa-miR-940	CLIP-seq
MIRT2029079	hsa-miR-1273	CLIP-seq
MIRT2029080	hsa-miR-4486	CLIP-seq
MIRT2029081	hsa-miR-4649-5p	CLIP-seq
MIRT2029082	hsa-miR-508-5p	CLIP-seq
MIRT2029083	hsa-miR-661	CLIP-seq
MIRT2029084	hsa-miR-766	CLIP-seq
MIRT1105503	hsa-miR-1225-3p	CLIP-seq
MIRT1105504	hsa-miR-1233	CLIP-seq
MIRT1105507	hsa-miR-4459	CLIP-seq
MIRT1105509	hsa-miR-665	CLIP-seq
MIRT1105503	hsa-miR-1225-3p	CLIP-seq
MIRT1105504	hsa-miR-1233	CLIP-seq
MIRT1105506	hsa-miR-1827	CLIP-seq
MIRT1105507	hsa-miR-4459	CLIP-seq
MIRT1105508	hsa-miR-4722-5p	CLIP-seq
MIRT1105509	hsa-miR-665	CLIP-seq
MIRT1105510	hsa-miR-940	CLIP-seq
MIRT2683815	hsa-miR-1291	CLIP-seq
MIRT2683816	hsa-miR-1324	CLIP-seq
MIRT2683817	hsa-miR-146b-3p	CLIP-seq
MIRT2683818	hsa-miR-4330	CLIP-seq
MIRT2683819	hsa-miR-4421	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0042692	Process	Muscle cell differentiation	ISS
GO:1904105	Process	Positive regulation of convergent extension involved in gastrulation	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IBA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:2000052	Process	Positive regulation of non-canonical Wnt signaling pathway	ISS

Other IDs

• MIM: 607164
• HGNC: 15525
• e!Ensembl: ENSG00000179528

Protein

• UniProt ID: Q6XYB7
• Protein name: Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2)
• Protein function: Transcription factor.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00046	Homeodomain	86 → 142	Homeodomain	Domain

• Sequence:

  MNSGREPRTPRTLLSIADILAPRMVPRAPSAPQLPESGPGPTSPLCALEELTSKTFRGLD
  ARALQPSEGRAGPDALGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLAT
  RLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSPEVLCSLALPEGAPDPGLCLGP
  AGPDSRPHLSDEEIQVDD

• Sequence length: 198

Related Genes

No strongly related genes found yet for LBX2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to LBX2.