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Gene Gene information from NCBI Gene database.
Entrez ID 9741
Gene name Lysosomal protein transmembrane 4 alpha
Gene symbol LAPTM4A
Synonyms (NCBI Gene)
HUMORF13LAPTM4MBNTMtrp
Chromosome 2
Chromosome location 2p24.1
Summary This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membr
miRNA miRNA information provided by mirtarbase database.
836 Show/Hide all (836)
miRTarBase ID miRNA Experiments Reference
MIRT022769 hsa-miR-124-3p Microarray 18668037
MIRT050931 hsa-miR-17-5p CLASH 23622248
MIRT493346 hsa-miR-519d-3p PAR-CLIP 20371350
MIRT493345 hsa-miR-20b-5p PAR-CLIP 20371350
MIRT493344 hsa-miR-93-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7 Show/Hide all (7)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21224396, 22096579, 32296183, 32814053
GO:0005765 Component Lysosomal membrane IBA
GO:0005765 Component Lysosomal membrane IDA 22096579
GO:0005794 Component Golgi apparatus IDA 10942595
GO:0012505 Component Endomembrane system IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
618837 6924 ENSG00000068697
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15012
Protein name Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembrane-spanning transporter MTP)
Protein function May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03821 Mtp 141 → 232 Golgi 4-transmembrane spanning transporter Family
PF03821 Mtp 36 → 157 Golgi 4-transmembrane spanning transporter Family
Sequence
MVSMSFKRNRSDRFYSTRCCGCCHVRTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAV
NIQYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVYGAISYQVGWLIPFFCYRLFDF
VLSCLVAISSLTYLPRIKEY
LDQLPDFPYKDDLLALDSSCLLFIVLVFFALFIIFKAYLI
NCVWNCYKYINNRNVPEIAVYPAFEAPPQYVLPTYEMAVKMPEKEPPPPYLP
A
Sequence length 233
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Lysosome