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Gene Gene information from NCBI Gene database.
Entrez ID 3846
Gene name Keratin associated protein 5-9
Gene symbol KRTAP5-9
Synonyms (NCBI Gene)
KRN1KRTAP5-1KRTAP5.9
Chromosome 11
Chromosome location 11q13.4
miRNA miRNA information provided by mirtarbase database.
34 Show/Hide all (34)
miRTarBase ID miRNA Experiments Reference
MIRT007147 hsa-miR-498 Luciferase reporter assay 23418466
MIRT007147 hsa-miR-498 Luciferase reporter assay 23418466
MIRT642942 hsa-miR-5088-5p HITS-CLIP 23824327
MIRT642941 hsa-miR-1288-5p HITS-CLIP 23824327
MIRT642940 hsa-miR-125a-5p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21516116, 23088713, 25416956, 25910212, 26871637, 29892012, 31515488, 32296183
GO:0005829 Component Cytosol TAS
GO:0005882 Component Intermediate filament IEA
GO:0008544 Process Epidermis development TAS 1703541
GO:0042802 Function Identical protein binding IPI 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
148021 23604 ENSG00000254997
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P26371
Protein name Keratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
Protein function In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their ex
Family and domains
Tissue specificity TISSUE SPECIFICITY: Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles. {ECO:0000269|PubMed:15144888}.
Sequence
MGCCGCSGGCGSSCGGCDSSCGSCGSGCRGCGPSCCAPVYCCKPVCCCVPACSCSSCGKR
GCGSCGGSKGGCGSCGCSQCSCCKPCCCSSGCGSSCCQCSCCKPYCSQCSCCKPCCSSSG
RGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVPVCYQCKI
Sequence length 169
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Keratinization