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Gene Gene information from NCBI Gene database.
Entrez ID 57830
Gene name Keratin associated protein 5-8
Gene symbol KRTAP5-8
Synonyms (NCBI Gene)
KRTAP5-2KRTAP5.8UHSKerB
Chromosome 11
Chromosome location 11q13.4
miRNA miRNA information provided by mirtarbase database.
38 Show/Hide all (38)
miRTarBase ID miRNA Experiments Reference
MIRT1102118 hsa-miR-1197 CLIP-seq
MIRT1102119 hsa-miR-139-5p CLIP-seq
MIRT1102120 hsa-miR-3929 CLIP-seq
MIRT1102121 hsa-miR-4257 CLIP-seq
MIRT1102122 hsa-miR-4320 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005829 Component Cytosol TAS
GO:0005882 Component Intermediate filament IEA
GO:0030280 Function Structural constituent of skin epidermis NAS 10023043
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75690
Protein name Keratin-associated protein 5-8 (Keratin, ultra high-sulfur matrix protein B) (Keratin-associated protein 5.8) (UHS keratin B) (UHS KerB) (Ultrahigh sulfur keratin-associated protein 5.8)
Protein function In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their ex
Family and domains
Tissue specificity TISSUE SPECIFICITY: Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles. {ECO:0000269|PubMed:15144888}.
Sequence
MGCCGCSGGCGSGCGGCGSGCGGCGSSCCVPICCCKPVCCCVPACSCSSCGSCGGSKGGR
GSCGGSKGDCGSCGGSKGGCGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPCCSQSSCC
KPCSCSSGCGSSCCQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCVP
ICCQCKI
Sequence length 187
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Keratinization