KLHL12 (kelch like family member 12)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 59349
• Gene name: Kelch like family member 12
• Gene symbol: KLHL12
• Synonyms (NCBI Gene): C3IP1, DKIR
• Chromosome: 1
• Chromosome location: 1q32.1
• Summary: This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren`s syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a su

miRNA Show/Hide all (437)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002506	hsa-miR-373-3p	Microarray	15685193
MIRT019284	hsa-miR-148b-3p	Microarray	17612493
MIRT002506	hsa-miR-373-3p	Microarray;Other	15685193
MIRT050001	hsa-miR-28-5p	CLASH	23622248
MIRT044028	hsa-miR-365a-3p	CLASH	23622248
MIRT619387	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT637272	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT619386	hsa-miR-4780	HITS-CLIP	23824327
MIRT619385	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT619384	hsa-miR-4469	HITS-CLIP	23824327
MIRT619383	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT619382	hsa-miR-4287	HITS-CLIP	23824327
MIRT619381	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT619380	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619379	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619378	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619377	hsa-miR-924	HITS-CLIP	23824327
MIRT619376	hsa-miR-623	HITS-CLIP	23824327
MIRT619375	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT619374	hsa-miR-627-5p	HITS-CLIP	23824327
MIRT619373	hsa-miR-4433b-5p	HITS-CLIP	23824327
MIRT619372	hsa-miR-4646-3p	HITS-CLIP	23824327
MIRT637274	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT619387	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT637273	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT637272	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT619386	hsa-miR-4780	HITS-CLIP	23824327
MIRT619385	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT619380	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619379	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619378	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619377	hsa-miR-924	HITS-CLIP	23824327
MIRT637271	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT637270	hsa-miR-491-5p	HITS-CLIP	23824327
MIRT637269	hsa-miR-3151-5p	HITS-CLIP	23824327
MIRT637267	hsa-miR-4447	HITS-CLIP	23824327
MIRT637268	hsa-miR-4472	HITS-CLIP	23824327
MIRT637266	hsa-miR-6742-5p	HITS-CLIP	23824327
MIRT619376	hsa-miR-623	HITS-CLIP	23824327
MIRT637265	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619374	hsa-miR-627-5p	HITS-CLIP	23824327
MIRT619373	hsa-miR-4433b-5p	HITS-CLIP	23824327
MIRT637264	hsa-miR-4265	HITS-CLIP	23824327
MIRT637263	hsa-miR-4296	HITS-CLIP	23824327
MIRT637261	hsa-miR-4322	HITS-CLIP	23824327
MIRT637262	hsa-miR-6796-5p	HITS-CLIP	23824327
MIRT637260	hsa-miR-6759-5p	HITS-CLIP	23824327
MIRT619372	hsa-miR-4646-3p	HITS-CLIP	23824327
MIRT637259	hsa-miR-2113	HITS-CLIP	23824327
MIRT637258	hsa-miR-5010-3p	HITS-CLIP	23824327
MIRT619387	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT619386	hsa-miR-4780	HITS-CLIP	23824327
MIRT619385	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT619384	hsa-miR-4469	HITS-CLIP	23824327
MIRT619383	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT619382	hsa-miR-4287	HITS-CLIP	23824327
MIRT619381	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT619380	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619379	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619378	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619377	hsa-miR-924	HITS-CLIP	23824327
MIRT619376	hsa-miR-623	HITS-CLIP	23824327
MIRT619375	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT619374	hsa-miR-627-5p	HITS-CLIP	23824327
MIRT619373	hsa-miR-4433b-5p	HITS-CLIP	23824327
MIRT619372	hsa-miR-4646-3p	HITS-CLIP	23824327
MIRT456403	hsa-miR-583	PAR-CLIP	23592263
MIRT456402	hsa-miR-4694-3p	PAR-CLIP	23592263
MIRT456401	hsa-miR-510-5p	PAR-CLIP	23592263
MIRT456400	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT456399	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT456398	hsa-miR-205-3p	PAR-CLIP	23592263
MIRT456397	hsa-miR-6501-3p	PAR-CLIP	23592263
MIRT456396	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT456395	hsa-miR-4270	PAR-CLIP	23592263
MIRT456394	hsa-miR-4441	PAR-CLIP	23592263
MIRT456393	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT456392	hsa-miR-1266-5p	PAR-CLIP	23592263
MIRT456391	hsa-miR-4518	PAR-CLIP	23592263
MIRT456390	hsa-miR-3148	PAR-CLIP	23592263
MIRT456389	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT456388	hsa-miR-3153	PAR-CLIP	23592263
MIRT456386	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT456387	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT456385	hsa-miR-3942-3p	PAR-CLIP	23592263
MIRT619387	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT637272	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT619386	hsa-miR-4780	HITS-CLIP	23824327
MIRT619385	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT619384	hsa-miR-4469	HITS-CLIP	23824327
MIRT619383	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT619382	hsa-miR-4287	HITS-CLIP	23824327
MIRT619381	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT619380	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619379	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619378	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619377	hsa-miR-924	HITS-CLIP	23824327
MIRT619376	hsa-miR-623	HITS-CLIP	23824327
MIRT619375	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT619374	hsa-miR-627-5p	HITS-CLIP	23824327
MIRT619373	hsa-miR-4433b-5p	HITS-CLIP	23824327
MIRT619372	hsa-miR-4646-3p	HITS-CLIP	23824327
MIRT637274	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT619387	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT637273	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT637272	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT619386	hsa-miR-4780	HITS-CLIP	23824327
MIRT619385	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT619380	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619379	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619378	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619377	hsa-miR-924	HITS-CLIP	23824327
MIRT637271	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT637270	hsa-miR-491-5p	HITS-CLIP	23824327
MIRT637269	hsa-miR-3151-5p	HITS-CLIP	23824327
MIRT637267	hsa-miR-4447	HITS-CLIP	23824327
MIRT637268	hsa-miR-4472	HITS-CLIP	23824327
MIRT637266	hsa-miR-6742-5p	HITS-CLIP	23824327
MIRT619376	hsa-miR-623	HITS-CLIP	23824327
MIRT637265	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619374	hsa-miR-627-5p	HITS-CLIP	23824327
MIRT619373	hsa-miR-4433b-5p	HITS-CLIP	23824327
MIRT637264	hsa-miR-4265	HITS-CLIP	23824327
MIRT637263	hsa-miR-4296	HITS-CLIP	23824327
MIRT637261	hsa-miR-4322	HITS-CLIP	23824327
MIRT637262	hsa-miR-6796-5p	HITS-CLIP	23824327
MIRT637260	hsa-miR-6759-5p	HITS-CLIP	23824327
MIRT619372	hsa-miR-4646-3p	HITS-CLIP	23824327
MIRT637259	hsa-miR-2113	HITS-CLIP	23824327
MIRT637258	hsa-miR-5010-3p	HITS-CLIP	23824327
MIRT619387	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT619386	hsa-miR-4780	HITS-CLIP	23824327
MIRT619385	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT619384	hsa-miR-4469	HITS-CLIP	23824327
MIRT619383	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT619382	hsa-miR-4287	HITS-CLIP	23824327
MIRT619381	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT619380	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619379	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619378	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619377	hsa-miR-924	HITS-CLIP	23824327
MIRT619376	hsa-miR-623	HITS-CLIP	23824327
MIRT619375	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT619374	hsa-miR-627-5p	HITS-CLIP	23824327
MIRT619373	hsa-miR-4433b-5p	HITS-CLIP	23824327
MIRT619372	hsa-miR-4646-3p	HITS-CLIP	23824327
MIRT456403	hsa-miR-583	PAR-CLIP	23592263
MIRT456402	hsa-miR-4694-3p	PAR-CLIP	23592263
MIRT456401	hsa-miR-510-5p	PAR-CLIP	23592263
MIRT456400	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT456399	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT456398	hsa-miR-205-3p	PAR-CLIP	23592263
MIRT456397	hsa-miR-6501-3p	PAR-CLIP	23592263
MIRT456396	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT456395	hsa-miR-4270	PAR-CLIP	23592263
MIRT456394	hsa-miR-4441	PAR-CLIP	23592263
MIRT456393	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT456392	hsa-miR-1266-5p	PAR-CLIP	23592263
MIRT456391	hsa-miR-4518	PAR-CLIP	23592263
MIRT456390	hsa-miR-3148	PAR-CLIP	23592263
MIRT456389	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT456388	hsa-miR-3153	PAR-CLIP	23592263
MIRT456386	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT456387	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT456385	hsa-miR-3942-3p	PAR-CLIP	23592263
MIRT1097474	hsa-let-7a	CLIP-seq
MIRT1097475	hsa-let-7b	CLIP-seq
MIRT1097476	hsa-let-7c	CLIP-seq
MIRT1097477	hsa-let-7d	CLIP-seq
MIRT1097478	hsa-let-7e	CLIP-seq
MIRT1097479	hsa-let-7f	CLIP-seq
MIRT1097480	hsa-let-7g	CLIP-seq
MIRT1097481	hsa-let-7i	CLIP-seq
MIRT1097482	hsa-miR-1266	CLIP-seq
MIRT1097483	hsa-miR-202	CLIP-seq
MIRT1097484	hsa-miR-3125	CLIP-seq
MIRT1097485	hsa-miR-3137	CLIP-seq
MIRT1097486	hsa-miR-3664-3p	CLIP-seq
MIRT1097487	hsa-miR-3916	CLIP-seq
MIRT1097488	hsa-miR-3928	CLIP-seq
MIRT1097489	hsa-miR-425	CLIP-seq
MIRT1097490	hsa-miR-4458	CLIP-seq
MIRT1097491	hsa-miR-4500	CLIP-seq
MIRT1097492	hsa-miR-4724-5p	CLIP-seq
MIRT1097493	hsa-miR-4738-3p	CLIP-seq
MIRT1097494	hsa-miR-4790-3p	CLIP-seq
MIRT1097495	hsa-miR-4793-3p	CLIP-seq
MIRT1097496	hsa-miR-483-3p	CLIP-seq
MIRT1097497	hsa-miR-510	CLIP-seq
MIRT1097498	hsa-miR-548b-3p	CLIP-seq
MIRT1097499	hsa-miR-592	CLIP-seq
MIRT1097500	hsa-miR-597	CLIP-seq
MIRT1097501	hsa-miR-642b	CLIP-seq
MIRT1097502	hsa-miR-873	CLIP-seq
MIRT1097503	hsa-miR-98	CLIP-seq
MIRT2026457	hsa-miR-1287	CLIP-seq
MIRT2026458	hsa-miR-3168	CLIP-seq
MIRT2026459	hsa-miR-3201	CLIP-seq
MIRT2026460	hsa-miR-3652	CLIP-seq
MIRT2026461	hsa-miR-3680	CLIP-seq
MIRT2026462	hsa-miR-375	CLIP-seq
MIRT2026463	hsa-miR-3929	CLIP-seq
MIRT2026464	hsa-miR-4419b	CLIP-seq
MIRT2026465	hsa-miR-4430	CLIP-seq
MIRT2026466	hsa-miR-4478	CLIP-seq
MIRT2026467	hsa-miR-4639-3p	CLIP-seq
MIRT2026468	hsa-miR-4728-3p	CLIP-seq
MIRT1097493	hsa-miR-4738-3p	CLIP-seq
MIRT2026469	hsa-miR-4791	CLIP-seq
MIRT2026470	hsa-miR-4798-3p	CLIP-seq
MIRT2026471	hsa-miR-491-3p	CLIP-seq
MIRT2026472	hsa-miR-561	CLIP-seq
MIRT2026473	hsa-miR-626	CLIP-seq
MIRT2026474	hsa-miR-645	CLIP-seq
MIRT2257552	hsa-miR-1207-5p	CLIP-seq
MIRT1097482	hsa-miR-1266	CLIP-seq
MIRT2257553	hsa-miR-1343	CLIP-seq
MIRT2257554	hsa-miR-188-3p	CLIP-seq
MIRT2257555	hsa-miR-218	CLIP-seq
MIRT2257556	hsa-miR-28-3p	CLIP-seq
MIRT2257557	hsa-miR-3074-5p	CLIP-seq
MIRT1097484	hsa-miR-3125	CLIP-seq
MIRT2257558	hsa-miR-3156-3p	CLIP-seq
MIRT2257559	hsa-miR-3166	CLIP-seq
MIRT2257560	hsa-miR-3189-3p	CLIP-seq
MIRT2257561	hsa-miR-3607-3p	CLIP-seq
MIRT2257562	hsa-miR-3690	CLIP-seq
MIRT1097487	hsa-miR-3916	CLIP-seq
MIRT1097488	hsa-miR-3928	CLIP-seq
MIRT1097489	hsa-miR-425	CLIP-seq
MIRT2257563	hsa-miR-4254	CLIP-seq
MIRT2257564	hsa-miR-4426	CLIP-seq
MIRT2257565	hsa-miR-4637	CLIP-seq
MIRT2257566	hsa-miR-4647	CLIP-seq
MIRT2257567	hsa-miR-4662b	CLIP-seq
MIRT2257568	hsa-miR-4668-3p	CLIP-seq
MIRT1097492	hsa-miR-4724-5p	CLIP-seq
MIRT2257569	hsa-miR-4736	CLIP-seq
MIRT2257570	hsa-miR-4763-3p	CLIP-seq
MIRT2257571	hsa-miR-4782-5p	CLIP-seq
MIRT1097494	hsa-miR-4790-3p	CLIP-seq
MIRT1097496	hsa-miR-483-3p	CLIP-seq
MIRT2257572	hsa-miR-576-3p	CLIP-seq
MIRT2257573	hsa-miR-636	CLIP-seq
MIRT1097501	hsa-miR-642b	CLIP-seq
MIRT2257574	hsa-miR-943	CLIP-seq
MIRT2389930	hsa-miR-330-3p	CLIP-seq
MIRT2389931	hsa-miR-4519	CLIP-seq
MIRT1097474	hsa-let-7a	CLIP-seq
MIRT1097475	hsa-let-7b	CLIP-seq
MIRT1097476	hsa-let-7c	CLIP-seq
MIRT1097477	hsa-let-7d	CLIP-seq
MIRT1097478	hsa-let-7e	CLIP-seq
MIRT1097479	hsa-let-7f	CLIP-seq
MIRT1097480	hsa-let-7g	CLIP-seq
MIRT1097481	hsa-let-7i	CLIP-seq
MIRT2558686	hsa-miR-106a	CLIP-seq
MIRT2558687	hsa-miR-106b	CLIP-seq
MIRT2558688	hsa-miR-1244	CLIP-seq
MIRT2558689	hsa-miR-1290	CLIP-seq
MIRT2558690	hsa-miR-17	CLIP-seq
MIRT2558691	hsa-miR-1825	CLIP-seq
MIRT2257554	hsa-miR-188-3p	CLIP-seq
MIRT2558692	hsa-miR-1914	CLIP-seq
MIRT2558693	hsa-miR-199a-5p	CLIP-seq
MIRT2558694	hsa-miR-199b-5p	CLIP-seq
MIRT1097483	hsa-miR-202	CLIP-seq
MIRT2558695	hsa-miR-205	CLIP-seq
MIRT2558696	hsa-miR-2054	CLIP-seq
MIRT2558697	hsa-miR-20a	CLIP-seq
MIRT2558698	hsa-miR-20b	CLIP-seq
MIRT2558699	hsa-miR-2355-3p	CLIP-seq
MIRT2257556	hsa-miR-28-3p	CLIP-seq
MIRT2558700	hsa-miR-2964a-5p	CLIP-seq
MIRT2558701	hsa-miR-302a	CLIP-seq
MIRT2558702	hsa-miR-302b	CLIP-seq
MIRT2558703	hsa-miR-302c	CLIP-seq
MIRT2558704	hsa-miR-302d	CLIP-seq
MIRT2558705	hsa-miR-302e	CLIP-seq
MIRT2558706	hsa-miR-3065-5p	CLIP-seq
MIRT2558707	hsa-miR-3121-3p	CLIP-seq
MIRT2558708	hsa-miR-3124-3p	CLIP-seq
MIRT1097484	hsa-miR-3125	CLIP-seq
MIRT2558709	hsa-miR-3163	CLIP-seq
MIRT2558710	hsa-miR-3190	CLIP-seq
MIRT2558711	hsa-miR-323b-5p	CLIP-seq
MIRT2389930	hsa-miR-330-3p	CLIP-seq
MIRT2558712	hsa-miR-342-3p	CLIP-seq
MIRT2026460	hsa-miR-3652	CLIP-seq
MIRT2558713	hsa-miR-3671	CLIP-seq
MIRT2558714	hsa-miR-372	CLIP-seq
MIRT2558715	hsa-miR-373	CLIP-seq
MIRT2026462	hsa-miR-375	CLIP-seq
MIRT2558716	hsa-miR-3911	CLIP-seq
MIRT1097487	hsa-miR-3916	CLIP-seq
MIRT2558717	hsa-miR-3925-3p	CLIP-seq
MIRT1097488	hsa-miR-3928	CLIP-seq
MIRT2026463	hsa-miR-3929	CLIP-seq
MIRT2558718	hsa-miR-409-3p	CLIP-seq
MIRT2558719	hsa-miR-4264	CLIP-seq
MIRT2558720	hsa-miR-4280	CLIP-seq
MIRT2026464	hsa-miR-4419b	CLIP-seq
MIRT2026465	hsa-miR-4430	CLIP-seq
MIRT1097490	hsa-miR-4458	CLIP-seq
MIRT2026466	hsa-miR-4478	CLIP-seq
MIRT1097491	hsa-miR-4500	CLIP-seq
MIRT2558721	hsa-miR-4509	CLIP-seq
MIRT2389931	hsa-miR-4519	CLIP-seq
MIRT2026467	hsa-miR-4639-3p	CLIP-seq
MIRT2257568	hsa-miR-4668-3p	CLIP-seq
MIRT2558722	hsa-miR-4679	CLIP-seq
MIRT2558723	hsa-miR-4690-3p	CLIP-seq
MIRT2558724	hsa-miR-4704-5p	CLIP-seq
MIRT2026468	hsa-miR-4728-3p	CLIP-seq
MIRT2558725	hsa-miR-4733-5p	CLIP-seq
MIRT1097493	hsa-miR-4738-3p	CLIP-seq
MIRT2558726	hsa-miR-4768-5p	CLIP-seq
MIRT2558727	hsa-miR-4774-5p	CLIP-seq
MIRT2558728	hsa-miR-4778-5p	CLIP-seq
MIRT1097494	hsa-miR-4790-3p	CLIP-seq
MIRT2558729	hsa-miR-4797-3p	CLIP-seq
MIRT1097496	hsa-miR-483-3p	CLIP-seq
MIRT2026471	hsa-miR-491-3p	CLIP-seq
MIRT2558730	hsa-miR-495	CLIP-seq
MIRT2558731	hsa-miR-519d	CLIP-seq
MIRT2558732	hsa-miR-520a-3p	CLIP-seq
MIRT2558733	hsa-miR-520b	CLIP-seq
MIRT2558734	hsa-miR-520c-3p	CLIP-seq
MIRT2558735	hsa-miR-520d-3p	CLIP-seq
MIRT2558736	hsa-miR-520e	CLIP-seq
MIRT2558737	hsa-miR-542-5p	CLIP-seq
MIRT2558738	hsa-miR-548g	CLIP-seq
MIRT2558739	hsa-miR-548u	CLIP-seq
MIRT2257572	hsa-miR-576-3p	CLIP-seq
MIRT2558740	hsa-miR-582-3p	CLIP-seq
MIRT2558741	hsa-miR-607	CLIP-seq
MIRT2026473	hsa-miR-626	CLIP-seq
MIRT2558742	hsa-miR-633	CLIP-seq
MIRT2558743	hsa-miR-640	CLIP-seq
MIRT1097501	hsa-miR-642b	CLIP-seq
MIRT2026474	hsa-miR-645	CLIP-seq
MIRT2558744	hsa-miR-648	CLIP-seq
MIRT2558745	hsa-miR-659	CLIP-seq
MIRT2558746	hsa-miR-668	CLIP-seq
MIRT2558747	hsa-miR-676	CLIP-seq
MIRT2558748	hsa-miR-766	CLIP-seq
MIRT2558749	hsa-miR-93	CLIP-seq
MIRT2558750	hsa-miR-942	CLIP-seq
MIRT1097503	hsa-miR-98	CLIP-seq
MIRT1097474	hsa-let-7a	CLIP-seq
MIRT1097475	hsa-let-7b	CLIP-seq
MIRT1097476	hsa-let-7c	CLIP-seq
MIRT1097477	hsa-let-7d	CLIP-seq
MIRT1097478	hsa-let-7e	CLIP-seq
MIRT1097479	hsa-let-7f	CLIP-seq
MIRT1097480	hsa-let-7g	CLIP-seq
MIRT1097481	hsa-let-7i	CLIP-seq
MIRT2558686	hsa-miR-106a	CLIP-seq
MIRT2558687	hsa-miR-106b	CLIP-seq
MIRT2558688	hsa-miR-1244	CLIP-seq
MIRT2558689	hsa-miR-1290	CLIP-seq
MIRT2558690	hsa-miR-17	CLIP-seq
MIRT2558691	hsa-miR-1825	CLIP-seq
MIRT2257554	hsa-miR-188-3p	CLIP-seq
MIRT2558692	hsa-miR-1914	CLIP-seq
MIRT2558693	hsa-miR-199a-5p	CLIP-seq
MIRT2558694	hsa-miR-199b-5p	CLIP-seq
MIRT1097483	hsa-miR-202	CLIP-seq
MIRT2558695	hsa-miR-205	CLIP-seq
MIRT2558696	hsa-miR-2054	CLIP-seq
MIRT2558697	hsa-miR-20a	CLIP-seq
MIRT2558698	hsa-miR-20b	CLIP-seq
MIRT2558699	hsa-miR-2355-3p	CLIP-seq
MIRT2257556	hsa-miR-28-3p	CLIP-seq
MIRT2558700	hsa-miR-2964a-5p	CLIP-seq
MIRT2558701	hsa-miR-302a	CLIP-seq
MIRT2558702	hsa-miR-302b	CLIP-seq
MIRT2558703	hsa-miR-302c	CLIP-seq
MIRT2558704	hsa-miR-302d	CLIP-seq
MIRT2558705	hsa-miR-302e	CLIP-seq
MIRT2558707	hsa-miR-3121-3p	CLIP-seq
MIRT1097484	hsa-miR-3125	CLIP-seq
MIRT2558709	hsa-miR-3163	CLIP-seq
MIRT2558710	hsa-miR-3190	CLIP-seq
MIRT2558711	hsa-miR-323b-5p	CLIP-seq
MIRT2389930	hsa-miR-330-3p	CLIP-seq
MIRT2558713	hsa-miR-3671	CLIP-seq
MIRT2558714	hsa-miR-372	CLIP-seq
MIRT2558715	hsa-miR-373	CLIP-seq
MIRT2026462	hsa-miR-375	CLIP-seq
MIRT2558716	hsa-miR-3911	CLIP-seq
MIRT1097487	hsa-miR-3916	CLIP-seq
MIRT2558717	hsa-miR-3925-3p	CLIP-seq
MIRT1097488	hsa-miR-3928	CLIP-seq
MIRT2558718	hsa-miR-409-3p	CLIP-seq
MIRT2558720	hsa-miR-4280	CLIP-seq
MIRT1097490	hsa-miR-4458	CLIP-seq
MIRT1097491	hsa-miR-4500	CLIP-seq
MIRT2558721	hsa-miR-4509	CLIP-seq
MIRT2389931	hsa-miR-4519	CLIP-seq
MIRT2026467	hsa-miR-4639-3p	CLIP-seq
MIRT2257568	hsa-miR-4668-3p	CLIP-seq
MIRT2558722	hsa-miR-4679	CLIP-seq
MIRT2558723	hsa-miR-4690-3p	CLIP-seq
MIRT2558724	hsa-miR-4704-5p	CLIP-seq
MIRT2026468	hsa-miR-4728-3p	CLIP-seq
MIRT2558725	hsa-miR-4733-5p	CLIP-seq
MIRT1097493	hsa-miR-4738-3p	CLIP-seq
MIRT2558726	hsa-miR-4768-5p	CLIP-seq
MIRT2558728	hsa-miR-4778-5p	CLIP-seq
MIRT2257571	hsa-miR-4782-5p	CLIP-seq
MIRT1097494	hsa-miR-4790-3p	CLIP-seq
MIRT1097496	hsa-miR-483-3p	CLIP-seq
MIRT2026471	hsa-miR-491-3p	CLIP-seq
MIRT2558730	hsa-miR-495	CLIP-seq
MIRT2558731	hsa-miR-519d	CLIP-seq
MIRT2558732	hsa-miR-520a-3p	CLIP-seq
MIRT2558733	hsa-miR-520b	CLIP-seq
MIRT2558734	hsa-miR-520c-3p	CLIP-seq
MIRT2558735	hsa-miR-520d-3p	CLIP-seq
MIRT2558736	hsa-miR-520e	CLIP-seq
MIRT2558737	hsa-miR-542-5p	CLIP-seq
MIRT2558739	hsa-miR-548u	CLIP-seq
MIRT2257572	hsa-miR-576-3p	CLIP-seq
MIRT2558741	hsa-miR-607	CLIP-seq
MIRT2026473	hsa-miR-626	CLIP-seq
MIRT2558742	hsa-miR-633	CLIP-seq
MIRT2558743	hsa-miR-640	CLIP-seq
MIRT1097501	hsa-miR-642b	CLIP-seq
MIRT2558744	hsa-miR-648	CLIP-seq
MIRT2558745	hsa-miR-659	CLIP-seq
MIRT2558746	hsa-miR-668	CLIP-seq
MIRT2558747	hsa-miR-676	CLIP-seq
MIRT2558748	hsa-miR-766	CLIP-seq
MIRT2558749	hsa-miR-93	CLIP-seq
MIRT2558750	hsa-miR-942	CLIP-seq
MIRT1097503	hsa-miR-98	CLIP-seq

Gene ontology (GO) Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 16713569, 17543862, 21145461, 21516116, 25416956, 27107012, 27716508, 30190310, 32296183, 32814053, 33961781, 34591642, 38270169
GO:0005737	Component	Cytoplasm	IBA
GO:0005829	Component	Cytosol	TAS
GO:0006513	Process	Protein monoubiquitination	IDA	22358839, 27716508
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IDA	22358839
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	27716508
GO:0009653	Process	Anatomical structure morphogenesis	IEA
GO:0009888	Process	Tissue development	IEA
GO:0014029	Process	Neural crest formation	IMP	27716508
GO:0014032	Process	Neural crest cell development	IMP	27716508
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016055	Process	Wnt signaling pathway	IMP	20970343
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0030127	Component	COPII vesicle coat	IDA	27716508
GO:0030134	Component	COPII-coated ER to Golgi transport vesicle	IBA
GO:0030134	Component	COPII-coated ER to Golgi transport vesicle	IDA	22358839
GO:0030134	Component	COPII-coated ER to Golgi transport vesicle	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IBA
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IDA	22358839
GO:0034451	Component	Centriolar satellite	IDA
GO:0042802	Function	Identical protein binding	IPI	16189514, 25416956, 27107012, 30190310, 32296183
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0048208	Process	COPII vesicle coating	IBA
GO:0048208	Process	COPII vesicle coating	IMP	22358839, 27716508
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IBA

Other IDs

• MIM: 614522
• HGNC: 19360
• e!Ensembl: ENSG00000117153

Protein

• UniProt ID: Q53G59
• Protein name: Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
• Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport (PubMed:22358839, PubMed:27565346). The BCR(KLHL12) complex is involved in ER-Golgi
• PDB: 2VPJ , 6TTK , 6V7O , 8OIO , 8RBH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	23 → 130	BTB/POZ domain	Domain
  PF01344	Kelch_1	462 → 507	Kelch motif	Repeat
  PF01344	Kelch_1	509 → 554	Kelch motif	Repeat
  PF01344	Kelch_1	415 → 460	Kelch motif	Repeat
  PF01344	Kelch_1	318 → 366	Kelch motif	Repeat
  PF01344	Kelch_1	368 → 413	Kelch motif	Repeat
  PF01344	Kelch_1	279 → 315	Kelch motif	Repeat
  PF07707	BACK	135 → 237	BTB And C-terminal Kelch	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. Highly expressed in testis and at lower levels in the submandibular salivary gland. {ECO:0000269|PubMed:15383316, ECO:0000269|PubMed:16108817}.
• Sequence:

  MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
  MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
  ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
  KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
  FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE
  KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY
  SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG
  LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG
  FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY
  DPIIDSWEVVTSMGTQRCDAGVCVLREK

• Sequence length: 568

Pathways

Reactome Pathway:

Degradation of DVL

Related Genes

No strongly related genes found yet for KLHL12.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to KLHL12.