Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	127707
Gene name	Kelch domain containing 7A
Gene symbol	KLHDC7A
Synonyms (NCBI Gene)	-
Chromosome	1
Chromosome location	1p36.13

106 Show/Hide all (106)

miRTarBase ID	miRNA	Experiments
MIRT1097348	hsa-miR-1208	CLIP-seq
MIRT1097349	hsa-miR-145	CLIP-seq
MIRT1097350	hsa-miR-1825	CLIP-seq
MIRT1097351	hsa-miR-1910	CLIP-seq
MIRT1097352	hsa-miR-194	CLIP-seq
MIRT1097353	hsa-miR-199a-5p	CLIP-seq
MIRT1097354	hsa-miR-199b-5p	CLIP-seq
MIRT1097355	hsa-miR-3121-5p	CLIP-seq
MIRT1097356	hsa-miR-3124-3p	CLIP-seq
MIRT1097357	hsa-miR-3180-5p	CLIP-seq
MIRT1097358	hsa-miR-330-3p	CLIP-seq
MIRT1097359	hsa-miR-370	CLIP-seq
MIRT1097360	hsa-miR-375	CLIP-seq
MIRT1097361	hsa-miR-409-3p	CLIP-seq
MIRT1097362	hsa-miR-4287	CLIP-seq
MIRT1097363	hsa-miR-4469	CLIP-seq
MIRT1097364	hsa-miR-4685-3p	CLIP-seq
MIRT1097365	hsa-miR-4778-3p	CLIP-seq
MIRT1097366	hsa-miR-494	CLIP-seq
MIRT1097367	hsa-miR-495	CLIP-seq
MIRT1097368	hsa-miR-501-5p	CLIP-seq
MIRT1097369	hsa-miR-548c-3p	CLIP-seq
MIRT1097370	hsa-miR-568	CLIP-seq
MIRT1097371	hsa-miR-643	CLIP-seq
MIRT1097372	hsa-miR-668	CLIP-seq
MIRT1097373	hsa-miR-873	CLIP-seq
MIRT1097374	hsa-miR-891b	CLIP-seq
MIRT2026406	hsa-miR-1184	CLIP-seq
MIRT2026407	hsa-miR-1205	CLIP-seq
MIRT2026408	hsa-miR-1305	CLIP-seq
MIRT2026409	hsa-miR-1324	CLIP-seq
MIRT2026410	hsa-miR-1343	CLIP-seq
MIRT1097349	hsa-miR-145	CLIP-seq
MIRT2026411	hsa-miR-150	CLIP-seq
MIRT1097350	hsa-miR-1825	CLIP-seq
MIRT1097353	hsa-miR-199a-5p	CLIP-seq
MIRT1097354	hsa-miR-199b-5p	CLIP-seq
MIRT2026412	hsa-miR-204	CLIP-seq
MIRT2026413	hsa-miR-211	CLIP-seq
MIRT1097356	hsa-miR-3124-3p	CLIP-seq
MIRT2026414	hsa-miR-3127-5p	CLIP-seq
MIRT2026415	hsa-miR-3158-5p	CLIP-seq
MIRT2026416	hsa-miR-3179	CLIP-seq
MIRT1097357	hsa-miR-3180-5p	CLIP-seq
MIRT1097358	hsa-miR-330-3p	CLIP-seq
MIRT2026417	hsa-miR-3667-3p	CLIP-seq
MIRT2026418	hsa-miR-4292	CLIP-seq
MIRT2026419	hsa-miR-4446-5p	CLIP-seq
MIRT2026420	hsa-miR-4639-3p	CLIP-seq
MIRT2026421	hsa-miR-4641	CLIP-seq
MIRT2026422	hsa-miR-4646-5p	CLIP-seq
MIRT2026423	hsa-miR-4690-3p	CLIP-seq
MIRT2026424	hsa-miR-4713-5p	CLIP-seq
MIRT2026425	hsa-miR-4728-3p	CLIP-seq
MIRT2026426	hsa-miR-4755-5p	CLIP-seq
MIRT1097366	hsa-miR-494	CLIP-seq
MIRT2026427	hsa-miR-532-3p	CLIP-seq
MIRT2026428	hsa-miR-623	CLIP-seq
MIRT1097372	hsa-miR-668	CLIP-seq
MIRT2257505	hsa-miR-1291	CLIP-seq
MIRT2026409	hsa-miR-1324	CLIP-seq
MIRT1097349	hsa-miR-145	CLIP-seq
MIRT1097350	hsa-miR-1825	CLIP-seq
MIRT1097353	hsa-miR-199a-5p	CLIP-seq
MIRT1097354	hsa-miR-199b-5p	CLIP-seq
MIRT2257506	hsa-miR-2276	CLIP-seq
MIRT2257507	hsa-miR-2355-5p	CLIP-seq
MIRT2257508	hsa-miR-3123	CLIP-seq
MIRT1097356	hsa-miR-3124-3p	CLIP-seq
MIRT1097357	hsa-miR-3180-5p	CLIP-seq
MIRT2257509	hsa-miR-328	CLIP-seq
MIRT2257510	hsa-miR-338-5p	CLIP-seq
MIRT2257511	hsa-miR-342-5p	CLIP-seq
MIRT2257512	hsa-miR-3925-5p	CLIP-seq
MIRT2257513	hsa-miR-3926	CLIP-seq
MIRT2257514	hsa-miR-3976	CLIP-seq
MIRT2257515	hsa-miR-4426	CLIP-seq
MIRT2257516	hsa-miR-4447	CLIP-seq
MIRT2257517	hsa-miR-4455	CLIP-seq
MIRT2257518	hsa-miR-4472	CLIP-seq
MIRT2257519	hsa-miR-4647	CLIP-seq
MIRT2257520	hsa-miR-4651	CLIP-seq
MIRT2257521	hsa-miR-4662b	CLIP-seq
MIRT2257522	hsa-miR-4664-5p	CLIP-seq
MIRT2257523	hsa-miR-4708-3p	CLIP-seq
MIRT2257524	hsa-miR-4729	CLIP-seq
MIRT1097366	hsa-miR-494	CLIP-seq
MIRT2257525	hsa-miR-548g	CLIP-seq
MIRT2257526	hsa-miR-548s	CLIP-seq
MIRT2257527	hsa-miR-608	CLIP-seq
MIRT2257528	hsa-miR-644	CLIP-seq
MIRT2257529	hsa-miR-663b	CLIP-seq
MIRT2257508	hsa-miR-3123	CLIP-seq
MIRT2257510	hsa-miR-338-5p	CLIP-seq
MIRT2257512	hsa-miR-3925-5p	CLIP-seq
MIRT2257514	hsa-miR-3976	CLIP-seq
MIRT1097366	hsa-miR-494	CLIP-seq
MIRT1097369	hsa-miR-548c-3p	CLIP-seq
MIRT1097373	hsa-miR-873	CLIP-seq
MIRT2257508	hsa-miR-3123	CLIP-seq
MIRT2257510	hsa-miR-338-5p	CLIP-seq
MIRT2257512	hsa-miR-3925-5p	CLIP-seq
MIRT2257514	hsa-miR-3976	CLIP-seq
MIRT1097366	hsa-miR-494	CLIP-seq
MIRT1097369	hsa-miR-548c-3p	CLIP-seq
MIRT1097373	hsa-miR-873	CLIP-seq

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q5VTJ3

Protein name

Kelch domain-containing protein 7A

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01344	Kelch_1	578 → 619	Kelch motif	Repeat
PF01344	Kelch_1	530 → 576	Kelch motif	Repeat

Sequence

MFPRGAEAQDWHLDMQLTGKVVLSAAALLLVTVAYRLYKSRPAPAQRWGGNGQAEAKEEA
EGSGQPAVQEASPGVLLRGPRRRRSSKRAEAPQGCSCENPRGPYVLVTGATSTDRKPQRK
GSGEERGGQGSDSEQVPPCCPSQETRTAVGSNPDPPHFPRLGSEPKSSPAGLIAAADGSC
AGGEPSPWQDSKPREHPGLGQLEPPHCHYVAPLQGSSDMNQSWVFTRVIGVSREEAGALE
AASDVDLTLHQQEGAPNSSYTFSSIARVRMEEHFIQKAEGVEPRLKGKVYDYYVESTSQA
IFQGRLAPRTAALTEVPSPRPPPGSLGTGAASGGQAGDTKGAAERAASPQTGPWPSTRGF
SRKESLLQIAENPELQLQPDGFRLPAPPCPDPGALPGLGRSSREPHVQPVAGTNFFHIPL
TPASAPQVRLDLGNCYEVLTLAKRQNLEALKEAAYKVMSENYLQVLRSPDIYGCLSGAER
ELILQRRLRGRQYLVVADVCPKEDSGGLCCYDDEQDVWRPLARMPPEAVSRGCAICSLFN
YLFVVSGCQGPGHQPSSRVFCYNPLTGIWSEVCPLNQARPHCRLVALDGHLYAIGGECLN
SVERYDPRLDRWDFAPPLPSDTFALAHTATVRAKEIFVTGGSLRFLLFRFSAQEQRWWAG
PTGGSKDRTAEMVAVNGFLYRFDLNRSLGIAVYRCSASTRLWYECATYRTPYPDAFQCAV
VDNLIYCVGRRSTLCFLADSVSPRFVPKELRSFPAPQGTLLPTVLTLPTPDLPQTRV

Sequence length

777

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal. Show/Hide Unknown Diseases (6)
BREAST CANCER	—	GWAS catalog	29059683, 32139696	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	29059683, 32139696	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST NEOPLASMS	—	CTD	29915430	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETIC RETINOPATHY	—	GWAS catalog	21441570	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	31969693	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PELVIC ORGAN PROLAPSE	—	GWAS catalog	26545240	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining Show/Hide Text Mining Associations (7)
Breast Carcinoma	Breast Carcinoma	CTD_human_DG	29915430	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	27607899	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic Retinopathy	BEFREE	27607899	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant neoplasm of breast	Breast Cancer	CTD_human_DG	29915430	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Carcinoma, Human	Marfan Syndrome	CTD_human_DG	29915430	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	CTD_human_DG	29915430	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms, Human	Mammary Neoplasms	CTD_human_DG	29915430	★★★★★ ★☆☆☆☆ Found in Text Mining only

KLHDC7A (kelch domain containing 7A)

Save This Analysis