KIF13A (kinesin family member 13A)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 63971 |
| Gene name | Kinesin family member 13A |
| Gene symbol | KIF13A |
| Synonyms (NCBI Gene) |
RBKINbA500C11.2
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| Chromosome | 6 |
| Chromosome location | 6p22.3 |
| Summary | This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma m |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9H1H9 | ||||||||||||||||||||||||||||||
| Protein name | Kinesin-like protein KIF13A (Kinesin-like protein RBKIN) | ||||||||||||||||||||||||||||||
| Protein function | Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenes | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed, with highest levels in heart, brain and skeletal muscle. {ECO:0000269|PubMed:11374900, ECO:0000269|PubMed:11861365}. | ||||||||||||||||||||||||||||||
| Sequence |
MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC |
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| Sequence length | 1805 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with KIF13A across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to KIF13A (see Related Genes above), that are NOT already directly curated for KIF13A itself -- a lead worth checking, not a confirmed association.
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