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Gene Gene information from NCBI Gene database.
Entrez ID 147040
Gene name Potassium channel tetramerization domain containing 11
Gene symbol KCTD11
Synonyms (NCBI Gene)
C17orf36KCASH1RENREN/KCTD11
Chromosome 17
Chromosome location 17p13.1
miRNA miRNA information provided by mirtarbase database.
863 Show/Hide all (863)
miRTarBase ID miRNA Experiments Reference
MIRT047562 hsa-miR-10a-5p CLASH 23622248
MIRT037456 hsa-miR-744-5p CLASH 23622248
MIRT506901 hsa-miR-329-3p HITS-CLIP 19536157
MIRT506900 hsa-miR-362-3p HITS-CLIP 19536157
MIRT506897 hsa-miR-8485 HITS-CLIP 19536157
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
SP1 Unknown 20591193
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16 Show/Hide all (16)
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IEA
GO:0007224 Process Smoothened signaling pathway IEA
GO:0007399 Process Nervous system development IEA
GO:0007405 Process Neuroblast proliferation IEA
GO:0007406 Process Negative regulation of neuroblast proliferation IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609848 21302 ENSG00000213859
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q693B1
Protein name BTB/POZ domain-containing protein KCTD11 (KCASH1 protein) (Potassium channel tetramerization domain-containing protein 11) (RING-type E3 ubiquitin transferase subunit KCTD11)
Protein function Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expr
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02214 BTB_2 7 → 73 BTB/POZ domain Domain
Tissue specificity TISSUE SPECIFICITY: Higher expression in cerebellum than in whole brain and lower expression in medulloblastoma. {ECO:0000269|PubMed:15249678}.
Sequence
MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAE
ADFYQIRPLLDAL
RELEASQGTPAPTAALLHADVDVSPRLVHFSARRGPHHYELSSVQVD
TFRANLFCTDSECLGALRARFGVASGDRAEGSPHFHLEWAPRPVELPEVEYGRLGLQPLW
TGGPGERREVVGTPSFLEEVLRVALEHGFRLDSVFPDPEDLLNSRSLRFVRH
Sequence length 232
Interactions View interactions