KCNS2 (potassium voltage-gated channel modifier subfamily S member 2)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 3788
• Gene name: Potassium voltage-gated channel modifier subfamily S member 2
• Gene symbol: KCNS2
• Synonyms (NCBI Gene): KV9.2
• Chromosome: 8
• Chromosome location: 8q22.2

miRNA Show/Hide all (76)

miRTarBase ID	miRNA	Experiments	Reference
MIRT051192	hsa-miR-16-5p	CLASH	23622248
MIRT719190	hsa-miR-548a-3p	HITS-CLIP	19536157
MIRT719189	hsa-miR-548ar-3p	HITS-CLIP	19536157
MIRT719188	hsa-miR-548az-3p	HITS-CLIP	19536157
MIRT719187	hsa-miR-548e-3p	HITS-CLIP	19536157
MIRT719186	hsa-miR-548f-3p	HITS-CLIP	19536157
MIRT719185	hsa-miR-5582-3p	HITS-CLIP	19536157
MIRT719184	hsa-miR-5583-3p	HITS-CLIP	19536157
MIRT719183	hsa-miR-888-3p	HITS-CLIP	19536157
MIRT719182	hsa-miR-183-5p	HITS-CLIP	19536157
MIRT719181	hsa-miR-371b-5p	HITS-CLIP	19536157
MIRT719180	hsa-miR-373-5p	HITS-CLIP	19536157
MIRT719179	hsa-miR-616-5p	HITS-CLIP	19536157
MIRT719178	hsa-miR-371a-5p	HITS-CLIP	19536157
MIRT719177	hsa-miR-372-5p	HITS-CLIP	19536157
MIRT719176	hsa-miR-6719-3p	HITS-CLIP	19536157
MIRT719175	hsa-miR-3913-3p	HITS-CLIP	19536157
MIRT719174	hsa-miR-3671	HITS-CLIP	19536157
MIRT719173	hsa-miR-489-3p	HITS-CLIP	19536157
MIRT719190	hsa-miR-548a-3p	HITS-CLIP	19536157
MIRT719189	hsa-miR-548ar-3p	HITS-CLIP	19536157
MIRT719188	hsa-miR-548az-3p	HITS-CLIP	19536157
MIRT719187	hsa-miR-548e-3p	HITS-CLIP	19536157
MIRT719186	hsa-miR-548f-3p	HITS-CLIP	19536157
MIRT719185	hsa-miR-5582-3p	HITS-CLIP	19536157
MIRT719184	hsa-miR-5583-3p	HITS-CLIP	19536157
MIRT719183	hsa-miR-888-3p	HITS-CLIP	19536157
MIRT719182	hsa-miR-183-5p	HITS-CLIP	19536157
MIRT719181	hsa-miR-371b-5p	HITS-CLIP	19536157
MIRT719180	hsa-miR-373-5p	HITS-CLIP	19536157
MIRT719179	hsa-miR-616-5p	HITS-CLIP	19536157
MIRT719178	hsa-miR-371a-5p	HITS-CLIP	19536157
MIRT719177	hsa-miR-372-5p	HITS-CLIP	19536157
MIRT719176	hsa-miR-6719-3p	HITS-CLIP	19536157
MIRT719175	hsa-miR-3913-3p	HITS-CLIP	19536157
MIRT719174	hsa-miR-3671	HITS-CLIP	19536157
MIRT719173	hsa-miR-489-3p	HITS-CLIP	19536157
MIRT1082423	hsa-miR-1276	CLIP-seq
MIRT1082424	hsa-miR-139-5p	CLIP-seq
MIRT1082425	hsa-miR-217	CLIP-seq
MIRT1082426	hsa-miR-2682	CLIP-seq
MIRT1082427	hsa-miR-299-3p	CLIP-seq
MIRT1082428	hsa-miR-3129-3p	CLIP-seq
MIRT1082429	hsa-miR-3143	CLIP-seq
MIRT1082430	hsa-miR-3151	CLIP-seq
MIRT1082431	hsa-miR-3173-3p	CLIP-seq
MIRT1082432	hsa-miR-342-3p	CLIP-seq
MIRT1082433	hsa-miR-342-5p	CLIP-seq
MIRT1082434	hsa-miR-34a	CLIP-seq
MIRT1082435	hsa-miR-34c-5p	CLIP-seq
MIRT1082436	hsa-miR-3620	CLIP-seq
MIRT1082437	hsa-miR-3714	CLIP-seq
MIRT1082438	hsa-miR-4261	CLIP-seq
MIRT1082439	hsa-miR-4311	CLIP-seq
MIRT1082440	hsa-miR-4447	CLIP-seq
MIRT1082441	hsa-miR-4472	CLIP-seq
MIRT1082442	hsa-miR-4496	CLIP-seq
MIRT1082443	hsa-miR-449a	CLIP-seq
MIRT1082444	hsa-miR-449b	CLIP-seq
MIRT1082445	hsa-miR-449c	CLIP-seq
MIRT1082446	hsa-miR-4504	CLIP-seq
MIRT1082447	hsa-miR-4509	CLIP-seq
MIRT1082448	hsa-miR-4651	CLIP-seq
MIRT1082449	hsa-miR-4664-5p	CLIP-seq
MIRT1082450	hsa-miR-4684-5p	CLIP-seq
MIRT1082451	hsa-miR-4704-3p	CLIP-seq
MIRT1082452	hsa-miR-4712-3p	CLIP-seq
MIRT1082453	hsa-miR-4729	CLIP-seq
MIRT1082454	hsa-miR-4744	CLIP-seq
MIRT1082455	hsa-miR-488	CLIP-seq
MIRT1082456	hsa-miR-491-5p	CLIP-seq
MIRT1082457	hsa-miR-543	CLIP-seq
MIRT1082458	hsa-miR-548an	CLIP-seq
MIRT1082459	hsa-miR-583	CLIP-seq
MIRT1082460	hsa-miR-608	CLIP-seq
MIRT1082461	hsa-miR-802	CLIP-seq

Gene ontology (GO) Show/Hide all (30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001508	Process	Action potential	IBA
GO:0005216	Function	Monoatomic ion channel activity	IEA
GO:0005249	Function	Voltage-gated potassium channel activity	IEA
GO:0005267	Function	Potassium channel activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006813	Process	Potassium ion transport	IEA
GO:0006813	Process	Potassium ion transport	ISS
GO:0008076	Component	Voltage-gated potassium channel complex	IBA
GO:0008076	Component	Voltage-gated potassium channel complex	IEA
GO:0008076	Component	Voltage-gated potassium channel complex	ISS
GO:0015459	Function	Potassium channel regulator activity	IBA
GO:0015459	Function	Potassium channel regulator activity	IEA
GO:0015459	Function	Potassium channel regulator activity	ISS
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034702	Component	Monoatomic ion channel complex	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	ISS
GO:0051260	Process	Protein homooligomerization	IEA
GO:0055085	Process	Transmembrane transport	IEA
GO:0071805	Process	Potassium ion transmembrane transport	IBA
GO:0071805	Process	Potassium ion transmembrane transport	IEA
GO:1901379	Process	Regulation of potassium ion transmembrane transport	IEA
GO:1901379	Process	Regulation of potassium ion transmembrane transport	ISS

Other IDs

• MIM: 602906
• HGNC: 6301
• e!Ensembl: ENSG00000156486

Protein

• UniProt ID: Q9ULS6
• Protein name: Delayed-rectifier potassium channel regulatory subunit KCNS2 (Delayed-rectifier K(+) channel alpha subunit 2) (Delayed-rectifier potassium channel subunit Kv9.2) (Potassium voltage-gated channel subfamily S member 2)
• Protein function: Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized va
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00520	Ion_trans	186 → 421	Ion transport protein	Family
  PF02214	BTB_2	19 → 118	BTB/POZ domain	Domain

• Sequence:

  MTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCD
  DYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCS
  YSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNP
  GYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTF
  ELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLM
  RIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLAT
  IPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQ
  KQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPSELSLNDSLR

• Sequence length: 477

Pathways

Reactome Pathway:

Voltage gated Potassium channels

Related Genes

No strongly related genes found yet for KCNS2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to KCNS2.