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Gene Gene information from NCBI Gene database.
Entrez ID 56888
Gene name Potassium channel modulatory factor 1
Gene symbol KCMF1
Synonyms (NCBI Gene)
DEBT91FIGCPCMFZZZ1
Chromosome 2
Chromosome location 2p11.2
miRNA miRNA information provided by mirtarbase database.
484 Show/Hide all (484)
miRTarBase ID miRNA Experiments Reference
MIRT438739 hsa-miR-210-3p Luciferase reporter assay 24980667
MIRT438739 hsa-miR-210-3p Luciferase reporter assay 24980667
MIRT438739 hsa-miR-210-3p Luciferase reporter assay 24980667
MIRT438739 hsa-miR-210-3p Luciferase reporter assay 24980667
MIRT674351 hsa-miR-6890-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30 Show/Hide all (30)
GO ID Ontology Definition Evidence Reference
GO:0002181 Process Cytoplasmic translation IC 23636399
GO:0005576 Component Extracellular region TAS
GO:0005737 Component Cytoplasm IDA 38297121
GO:0005737 Component Cytoplasm IEA
GO:0005764 Component Lysosome IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
614719 20589 ENSG00000176407
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9P0J7
Protein name E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (FGF-induced in gastric cancer) (Potassium channel modulatory factor) (PCMF) (ZZ-type zinc finger-containing protein 1)
Protein function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and then transfers it to targeted substrates, promoting their degradation by the proteasome (PubMed:15581609, PubMed:25582440, PubMed:34893540, PubMed:37
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00569 ZZ 3 → 48 Zinc finger, ZZ type Domain
PF05605 zf-Di19 76 → 137 Drought induced 19 protein (Di19), zinc-binding Domain
Tissue specificity TISSUE SPECIFICITY: Spleen, small intestine, ovary, peripheral blood, lung, kidney and pancreas. Expressed at low levels in the thymus, prostate, testis, colon, heart, brain, placenta and liver. {ECO:0000269|PubMed:15581609}.
Sequence
MSRHEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESGATTTRHTTDHPMQCILTRVD
FDLYYGGEAFSVEQPQSFTCPYCGKMGYTETSLQEHVTSEHAETSTEVICPICAALPGGD
PNHVTDDFAAHLTLEHR
APRDLDESSGVRHVRRMFHPGRGLGGPRARRSNMHFTSSSTGG
LSSSQSSYSPSNREAMDPIAELLSQLSGVRRSAGGQLNSSGPSASQLQQLQMQLQLERQH
AQAARQQLETARNATRRTNTSSVTTTITQSTATTNIANTESSQQTLQNSQFLLTRLNDPK
MSETERQSMESERADRSLFVQELLLSTLVREESSSSDEDDRGEMADFGAMGCVDIMPLDV
ALENLNLKESNKGNEPPPPPL
Sequence length 381
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Neutrophil degranulation