KBTBD2 (kelch repeat and BTB domain containing 2)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 25948 |
| Gene name | Kelch repeat and BTB domain containing 2 |
| Gene symbol | KBTBD2 |
| Synonyms (NCBI Gene) |
BKLHD1
|
| Chromosome | 7 |
| Chromosome location | 7p14.3 |
|
miRNA
miRNA information provided by mirtarbase database.
494
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q8IY47 | ||||||||||||||||||||
| Protein name | Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1) | ||||||||||||||||||||
| Protein function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of the insulin signaling pathway, modulating insulin sensitivity by limiting PIK3R1/p85alpha abundance in adipocytes. Targets PIK3R1, the re | ||||||||||||||||||||
| PDB | 8GQ6 , 8H33 , 8H34 , 8H35 , 8H36 , 8H37 , 8H38 , 8H3A , 8H3F , 8H3R | ||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||
| Sequence |
MSTQDERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMF |
||||||||||||||||||||
| Sequence length | 623 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
|
Related Genes
Genes most often co-reported with KBTBD2 across shared curated disease and pathway associations.
0
|
|
|
Diseases Linked via Similar Genes
Diseases curated for genes most similar to KBTBD2 (see Related Genes above), that are NOT already directly curated for KBTBD2 itself -- a lead worth checking, not a confirmed association.
0
|
|