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Gene Gene information from NCBI Gene database.
Entrez ID 9929
Gene name Josephin domain containing 1
Gene symbol JOSD1
Synonyms (NCBI Gene)
dJ508I15.2
Chromosome 22
Chromosome location 22q13.1
miRNA miRNA information provided by mirtarbase database.
553 Show/Hide all (553)
miRTarBase ID miRNA Experiments Reference
MIRT029639 hsa-miR-26b-5p Microarray 19088304
MIRT045025 hsa-miR-186-5p CLASH 23622248
MIRT475052 hsa-miR-107 PAR-CLIP 23592263
MIRT475051 hsa-miR-103a-3p PAR-CLIP 23592263
MIRT475050 hsa-miR-4796-3p PAR-CLIP 23592263
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21 Show/Hide all (21)
GO ID Ontology Definition Evidence Reference
GO:0004843 Function Cysteine-type deubiquitinase activity IBA
GO:0004843 Function Cysteine-type deubiquitinase activity IEA
GO:0004843 Function Cysteine-type deubiquitinase activity TAS
GO:0005515 Function Protein binding IPI 21516116, 25416956, 32296183
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615323 28953 ENSG00000100221
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15040
Protein name Josephin-1 (EC 3.4.19.12) (Josephin domain-containing protein 1)
Protein function Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathri
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02099 Josephin 31 → 188 Josephin Family
Sequence
Sequence length 202
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Josephin domain DUBs