JMJD4 (jumonji domain containing 4)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 65094
• Gene name: Jumonji domain containing 4
• Gene symbol: JMJD4
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1q42.13

miRNA Show/Hide all (185)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027810	hsa-miR-98-5p	Microarray	19088304
MIRT043597	hsa-miR-148b-3p	CLASH	23622248
MIRT710223	hsa-miR-1972	HITS-CLIP	19536157
MIRT710222	hsa-miR-4650-5p	HITS-CLIP	19536157
MIRT710221	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT710220	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710219	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT710218	hsa-miR-2276-3p	HITS-CLIP	19536157
MIRT710217	hsa-miR-4696	HITS-CLIP	19536157
MIRT710216	hsa-miR-661	HITS-CLIP	19536157
MIRT710215	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT710214	hsa-miR-6780a-3p	HITS-CLIP	19536157
MIRT710223	hsa-miR-1972	HITS-CLIP	19536157
MIRT710222	hsa-miR-4650-5p	HITS-CLIP	19536157
MIRT710221	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT710220	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710219	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT710218	hsa-miR-2276-3p	HITS-CLIP	19536157
MIRT710217	hsa-miR-4696	HITS-CLIP	19536157
MIRT710216	hsa-miR-661	HITS-CLIP	19536157
MIRT710215	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT710214	hsa-miR-6780a-3p	HITS-CLIP	19536157
MIRT1076875	hsa-miR-1185	CLIP-seq
MIRT1076876	hsa-miR-1254	CLIP-seq
MIRT1076877	hsa-miR-125a-3p	CLIP-seq
MIRT1076878	hsa-miR-1287	CLIP-seq
MIRT1076879	hsa-miR-1291	CLIP-seq
MIRT1076880	hsa-miR-15a	CLIP-seq
MIRT1076881	hsa-miR-15b	CLIP-seq
MIRT1076882	hsa-miR-16	CLIP-seq
MIRT1076883	hsa-miR-1827	CLIP-seq
MIRT1076884	hsa-miR-1912	CLIP-seq
MIRT1076885	hsa-miR-195	CLIP-seq
MIRT1076886	hsa-miR-199a-5p	CLIP-seq
MIRT1076887	hsa-miR-199b-5p	CLIP-seq
MIRT1076888	hsa-miR-214	CLIP-seq
MIRT1076889	hsa-miR-2682	CLIP-seq
MIRT1076890	hsa-miR-3116	CLIP-seq
MIRT1076891	hsa-miR-3130-5p	CLIP-seq
MIRT1076892	hsa-miR-3135b	CLIP-seq
MIRT1076893	hsa-miR-3144-5p	CLIP-seq
MIRT1076894	hsa-miR-3173-5p	CLIP-seq
MIRT1076895	hsa-miR-3184	CLIP-seq
MIRT1076896	hsa-miR-3187-3p	CLIP-seq
MIRT1076897	hsa-miR-3191	CLIP-seq
MIRT1076898	hsa-miR-342-5p	CLIP-seq
MIRT1076899	hsa-miR-34a	CLIP-seq
MIRT1076900	hsa-miR-34c-5p	CLIP-seq
MIRT1076901	hsa-miR-3605-5p	CLIP-seq
MIRT1076902	hsa-miR-3611	CLIP-seq
MIRT1076903	hsa-miR-3612	CLIP-seq
MIRT1076904	hsa-miR-3615	CLIP-seq
MIRT1076905	hsa-miR-3619-5p	CLIP-seq
MIRT1076906	hsa-miR-3677-5p	CLIP-seq
MIRT1076907	hsa-miR-3679-5p	CLIP-seq
MIRT1076908	hsa-miR-378	CLIP-seq
MIRT1076909	hsa-miR-378b	CLIP-seq
MIRT1076910	hsa-miR-378c	CLIP-seq
MIRT1076911	hsa-miR-378d	CLIP-seq
MIRT1076912	hsa-miR-378e	CLIP-seq
MIRT1076913	hsa-miR-378f	CLIP-seq
MIRT1076914	hsa-miR-378h	CLIP-seq
MIRT1076915	hsa-miR-378i	CLIP-seq
MIRT1076916	hsa-miR-3925-3p	CLIP-seq
MIRT1076917	hsa-miR-422a	CLIP-seq
MIRT1076918	hsa-miR-423-5p	CLIP-seq
MIRT1076919	hsa-miR-424	CLIP-seq
MIRT1076920	hsa-miR-4254	CLIP-seq
MIRT1076921	hsa-miR-4267	CLIP-seq
MIRT1076922	hsa-miR-4269	CLIP-seq
MIRT1076923	hsa-miR-4291	CLIP-seq
MIRT1076924	hsa-miR-4299	CLIP-seq
MIRT1076925	hsa-miR-4302	CLIP-seq
MIRT1076926	hsa-miR-4316	CLIP-seq
MIRT1076927	hsa-miR-4443	CLIP-seq
MIRT1076928	hsa-miR-4482	CLIP-seq
MIRT1076929	hsa-miR-4492	CLIP-seq
MIRT1076930	hsa-miR-4498	CLIP-seq
MIRT1076931	hsa-miR-449a	CLIP-seq
MIRT1076932	hsa-miR-449b	CLIP-seq
MIRT1076933	hsa-miR-449c	CLIP-seq
MIRT1076934	hsa-miR-4505	CLIP-seq
MIRT1076935	hsa-miR-4514	CLIP-seq
MIRT1076936	hsa-miR-4529-5p	CLIP-seq
MIRT1076937	hsa-miR-4645-5p	CLIP-seq
MIRT1076938	hsa-miR-4651	CLIP-seq
MIRT1076939	hsa-miR-4652-5p	CLIP-seq
MIRT1076940	hsa-miR-4664-5p	CLIP-seq
MIRT1076941	hsa-miR-4667-5p	CLIP-seq
MIRT1076942	hsa-miR-4673	CLIP-seq
MIRT1076943	hsa-miR-4692	CLIP-seq
MIRT1076944	hsa-miR-4700-5p	CLIP-seq
MIRT1076945	hsa-miR-4709-3p	CLIP-seq
MIRT1076946	hsa-miR-4710	CLIP-seq
MIRT1076947	hsa-miR-4731-5p	CLIP-seq
MIRT1076948	hsa-miR-4757-5p	CLIP-seq
MIRT1076949	hsa-miR-4792	CLIP-seq
MIRT1076950	hsa-miR-487a	CLIP-seq
MIRT1076951	hsa-miR-497	CLIP-seq
MIRT1076952	hsa-miR-608	CLIP-seq
MIRT1076953	hsa-miR-650	CLIP-seq
MIRT1076954	hsa-miR-663b	CLIP-seq
MIRT1076955	hsa-miR-761	CLIP-seq
MIRT1076956	hsa-miR-762	CLIP-seq
MIRT1076957	hsa-miR-766	CLIP-seq
MIRT1076958	hsa-miR-922	CLIP-seq
MIRT1076883	hsa-miR-1827	CLIP-seq
MIRT1076888	hsa-miR-214	CLIP-seq
MIRT2019136	hsa-miR-3194-5p	CLIP-seq
MIRT1076898	hsa-miR-342-5p	CLIP-seq
MIRT1076905	hsa-miR-3619-5p	CLIP-seq
MIRT2019137	hsa-miR-3689d	CLIP-seq
MIRT2019138	hsa-miR-370	CLIP-seq
MIRT1076926	hsa-miR-4316	CLIP-seq
MIRT1076938	hsa-miR-4651	CLIP-seq
MIRT1076940	hsa-miR-4664-5p	CLIP-seq
MIRT2019139	hsa-miR-4690-5p	CLIP-seq
MIRT1076946	hsa-miR-4710	CLIP-seq
MIRT1076947	hsa-miR-4731-5p	CLIP-seq
MIRT1076952	hsa-miR-608	CLIP-seq
MIRT1076955	hsa-miR-761	CLIP-seq
MIRT1076875	hsa-miR-1185	CLIP-seq
MIRT2251045	hsa-miR-124	CLIP-seq
MIRT1076877	hsa-miR-125a-3p	CLIP-seq
MIRT1076880	hsa-miR-15a	CLIP-seq
MIRT1076881	hsa-miR-15b	CLIP-seq
MIRT1076882	hsa-miR-16	CLIP-seq
MIRT1076884	hsa-miR-1912	CLIP-seq
MIRT1076885	hsa-miR-195	CLIP-seq
MIRT1076886	hsa-miR-199a-5p	CLIP-seq
MIRT1076887	hsa-miR-199b-5p	CLIP-seq
MIRT2251046	hsa-miR-2114	CLIP-seq
MIRT1076888	hsa-miR-214	CLIP-seq
MIRT1076891	hsa-miR-3130-5p	CLIP-seq
MIRT2251047	hsa-miR-3134	CLIP-seq
MIRT1076893	hsa-miR-3144-5p	CLIP-seq
MIRT1076895	hsa-miR-3184	CLIP-seq
MIRT1076897	hsa-miR-3191	CLIP-seq
MIRT1076901	hsa-miR-3605-5p	CLIP-seq
MIRT1076902	hsa-miR-3611	CLIP-seq
MIRT1076903	hsa-miR-3612	CLIP-seq
MIRT1076905	hsa-miR-3619-5p	CLIP-seq
MIRT2251048	hsa-miR-3622a-3p	CLIP-seq
MIRT2251049	hsa-miR-3622b-3p	CLIP-seq
MIRT2251050	hsa-miR-362-5p	CLIP-seq
MIRT1076907	hsa-miR-3679-5p	CLIP-seq
MIRT2019137	hsa-miR-3689d	CLIP-seq
MIRT2251051	hsa-miR-3919	CLIP-seq
MIRT1076918	hsa-miR-423-5p	CLIP-seq
MIRT1076919	hsa-miR-424	CLIP-seq
MIRT1076920	hsa-miR-4254	CLIP-seq
MIRT1076922	hsa-miR-4269	CLIP-seq
MIRT1076923	hsa-miR-4291	CLIP-seq
MIRT1076925	hsa-miR-4302	CLIP-seq
MIRT2251052	hsa-miR-4420	CLIP-seq
MIRT1076927	hsa-miR-4443	CLIP-seq
MIRT2251053	hsa-miR-4477a	CLIP-seq
MIRT1076928	hsa-miR-4482	CLIP-seq
MIRT1076929	hsa-miR-4492	CLIP-seq
MIRT1076930	hsa-miR-4498	CLIP-seq
MIRT1076934	hsa-miR-4505	CLIP-seq
MIRT2251054	hsa-miR-4534	CLIP-seq
MIRT1076939	hsa-miR-4652-5p	CLIP-seq
MIRT1076941	hsa-miR-4667-5p	CLIP-seq
MIRT2019139	hsa-miR-4690-5p	CLIP-seq
MIRT1076944	hsa-miR-4700-5p	CLIP-seq
MIRT1076945	hsa-miR-4709-3p	CLIP-seq
MIRT1076946	hsa-miR-4710	CLIP-seq
MIRT2251055	hsa-miR-4726-3p	CLIP-seq
MIRT1076947	hsa-miR-4731-5p	CLIP-seq
MIRT2251056	hsa-miR-4802-5p	CLIP-seq
MIRT1076951	hsa-miR-497	CLIP-seq
MIRT2251057	hsa-miR-500b	CLIP-seq
MIRT2251058	hsa-miR-506	CLIP-seq
MIRT2251059	hsa-miR-619	CLIP-seq
MIRT1076953	hsa-miR-650	CLIP-seq
MIRT1076955	hsa-miR-761	CLIP-seq
MIRT1076956	hsa-miR-762	CLIP-seq
MIRT1076958	hsa-miR-922	CLIP-seq
MIRT2251046	hsa-miR-2114	CLIP-seq
MIRT1076888	hsa-miR-214	CLIP-seq
MIRT1076905	hsa-miR-3619-5p	CLIP-seq
MIRT1076922	hsa-miR-4269	CLIP-seq
MIRT2019139	hsa-miR-4690-5p	CLIP-seq
MIRT1076955	hsa-miR-761	CLIP-seq

Gene ontology (GO) Show/Hide all (20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	24360279, 24486019
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	24486019
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0010468	Process	Regulation of gene expression	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016706	Function	2-oxoglutarate-dependent dioxygenase activity	IBA
GO:0016706	Function	2-oxoglutarate-dependent dioxygenase activity	IEA
GO:0016706	Function	2-oxoglutarate-dependent dioxygenase activity	IMP	24486019
GO:0018126	Process	Protein hydroxylation	IMP	24486019
GO:0043565	Function	Sequence-specific DNA binding	IBA
GO:0045905	Process	Positive regulation of translational termination	IBA
GO:0045905	Process	Positive regulation of translational termination	IMP	24486019
GO:0046872	Function	Metal ion binding	IEA
GO:0051213	Function	Dioxygenase activity	IEA
GO:0106156	Function	Peptidyl-lysine 4-dioxygenase activity	EXP	24486019
GO:0106156	Function	Peptidyl-lysine 4-dioxygenase activity	IEA
GO:0140096	Function	Catalytic activity, acting on a protein	IEA

Other IDs

• MIM: 620928
• HGNC: 25724
• e!Ensembl: ENSG00000081692

Protein

• UniProt ID: Q9H9V9
• Protein name: 2-oxoglutarate and iron-dependent oxygenase JMJD4 (EC 1.14.11.-) (JmjC domain-containing protein 4) (Jumonji domain-containing protein 4) (Lysyl-hydroxylase JMJD4)
• Protein function: Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02373	JmjC	222 → 330	JmjC domain, hydroxylase	Domain

• Sequence:

  MRAGPEPQALAGQKRGALRLLVPRLVLTVSAPAEVRRRVLRPVLSWMDRETRALADSHFR
  GLGVDVPGVGQAPGRVAFVSEPGAFSYADFVRGFLLPNLPCVFSSAFTQGWGSRRRWVTP
  AGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYITYWKEYIQAGYSSPRGCL
  YLKDWHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRFVYAGPAGSWSPFHADIFR
  SFSWSVNVCGRKKWLLFPPGQEEALRDRHGNLPYDVTSPALCDTHLHPRNQLAGPPLEIT
  QEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMWRFLQQELCAVQEEVSEWRDS
  MPDWHHHCQVIMRSCSGINFEEFYHFLKVIAEKRLLVLREAAAEDGAGLGFEQAAFDVGR
  ITEVLASLVAHPDFQRVDTSAFSPQPKELLQQLREAVDAAAAP

• Sequence length: 463

Related Genes

No strongly related genes found yet for JMJD4.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to JMJD4.