ISG20L2 (interferon stimulated exonuclease gene 20 like 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 81875 |
| Gene name | Interferon stimulated exonuclease gene 20 like 2 |
| Gene symbol | ISG20L2 |
| Synonyms (NCBI Gene) |
HSD38
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| Chromosome | 1 |
| Chromosome location | 1q23.1 |
| Summary | This gene encodes a 3`-5` exoribonuclease that may be involved in the processing of the 12S pre-rRNA. Pseudogenes have been identified on chromosomes 6 and 11. [provided by RefSeq, Dec 2014] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9H9L3 | ||||||||||
| Protein name | Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-) | ||||||||||
| Protein function | 3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Displays a strong specificity for a 3'-end containing a free hydroxyl group. | ||||||||||
| PDB | 7YW5 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MSTLLLNLDFGEPPPKKALEGNAKHRNFVKKRRLLERRGFLSKKNQPPSKAPKLHSEPSK |
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| Sequence length | 353 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with ISG20L2 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to ISG20L2 (see Related Genes above), that are NOT already directly curated for ISG20L2 itself -- a lead worth checking, not a confirmed association.
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