ISCA1 (iron-sulfur cluster assembly 1)

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Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 81689
• Gene name: Iron-sulfur cluster assembly 1
• Gene symbol: ISCA1
• Synonyms (NCBI Gene): HBLD2, ISA1, MMDS5, hIscA, hIscA1
• Chromosome: 9
• Chromosome location: 9q21.33
• Summary: ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions (Cozar-Castellano et al., 2004 [PubMed 15262227]).[supplied by OMIM, Mar 2008]

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs776679653	C>T	Pathogenic	Coding sequence variant, missense variant
rs1587823007	A>C	Pathogenic	Missense variant, coding sequence variant

miRNA Show/Hide all (262)

miRTarBase ID	miRNA	Experiments	Reference
MIRT047223	hsa-miR-181c-5p	CLASH	23622248
MIRT563453	hsa-miR-4311	PAR-CLIP	20371350
MIRT563452	hsa-miR-1276	PAR-CLIP	20371350
MIRT563451	hsa-miR-583	PAR-CLIP	20371350
MIRT563449	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT563450	hsa-miR-1254	PAR-CLIP	20371350
MIRT563448	hsa-miR-3116	PAR-CLIP	20371350
MIRT563447	hsa-miR-661	PAR-CLIP	20371350
MIRT563445	hsa-miR-6894-3p	PAR-CLIP	20371350
MIRT563446	hsa-miR-6514-3p	PAR-CLIP	20371350
MIRT563444	hsa-miR-4774-3p	PAR-CLIP	20371350
MIRT563443	hsa-miR-3152-5p	PAR-CLIP	20371350
MIRT563453	hsa-miR-4311	PAR-CLIP	20371350
MIRT563452	hsa-miR-1276	PAR-CLIP	20371350
MIRT563451	hsa-miR-583	PAR-CLIP	20371350
MIRT563449	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT563450	hsa-miR-1254	PAR-CLIP	20371350
MIRT563448	hsa-miR-3116	PAR-CLIP	20371350
MIRT563447	hsa-miR-661	PAR-CLIP	20371350
MIRT563445	hsa-miR-6894-3p	PAR-CLIP	20371350
MIRT563446	hsa-miR-6514-3p	PAR-CLIP	20371350
MIRT563444	hsa-miR-4774-3p	PAR-CLIP	20371350
MIRT563443	hsa-miR-3152-5p	PAR-CLIP	20371350
MIRT487949	hsa-miR-624-3p	PAR-CLIP	23592263
MIRT487948	hsa-miR-5007-5p	PAR-CLIP	23592263
MIRT487947	hsa-miR-2114-5p	PAR-CLIP	23592263
MIRT487946	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT487945	hsa-miR-8085	PAR-CLIP	23592263
MIRT487944	hsa-miR-3175	PAR-CLIP	23592263
MIRT487943	hsa-miR-6835-5p	PAR-CLIP	23592263
MIRT487942	hsa-miR-197-5p	PAR-CLIP	23592263
MIRT487941	hsa-miR-3132	PAR-CLIP	23592263
MIRT487940	hsa-miR-4451	PAR-CLIP	23592263
MIRT563453	hsa-miR-4311	PAR-CLIP	20371350
MIRT563452	hsa-miR-1276	PAR-CLIP	20371350
MIRT563451	hsa-miR-583	PAR-CLIP	20371350
MIRT563449	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT563450	hsa-miR-1254	PAR-CLIP	20371350
MIRT563448	hsa-miR-3116	PAR-CLIP	20371350
MIRT563447	hsa-miR-661	PAR-CLIP	20371350
MIRT563445	hsa-miR-6894-3p	PAR-CLIP	20371350
MIRT563446	hsa-miR-6514-3p	PAR-CLIP	20371350
MIRT563444	hsa-miR-4774-3p	PAR-CLIP	20371350
MIRT563443	hsa-miR-3152-5p	PAR-CLIP	20371350
MIRT563453	hsa-miR-4311	PAR-CLIP	20371350
MIRT563452	hsa-miR-1276	PAR-CLIP	20371350
MIRT563451	hsa-miR-583	PAR-CLIP	20371350
MIRT563449	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT563450	hsa-miR-1254	PAR-CLIP	20371350
MIRT563448	hsa-miR-3116	PAR-CLIP	20371350
MIRT563447	hsa-miR-661	PAR-CLIP	20371350
MIRT563445	hsa-miR-6894-3p	PAR-CLIP	20371350
MIRT563446	hsa-miR-6514-3p	PAR-CLIP	20371350
MIRT563444	hsa-miR-4774-3p	PAR-CLIP	20371350
MIRT563443	hsa-miR-3152-5p	PAR-CLIP	20371350
MIRT487949	hsa-miR-624-3p	PAR-CLIP	23592263
MIRT487948	hsa-miR-5007-5p	PAR-CLIP	23592263
MIRT487947	hsa-miR-2114-5p	PAR-CLIP	23592263
MIRT487946	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT487945	hsa-miR-8085	PAR-CLIP	23592263
MIRT487944	hsa-miR-3175	PAR-CLIP	23592263
MIRT487943	hsa-miR-6835-5p	PAR-CLIP	23592263
MIRT487942	hsa-miR-197-5p	PAR-CLIP	23592263
MIRT487941	hsa-miR-3132	PAR-CLIP	23592263
MIRT487940	hsa-miR-4451	PAR-CLIP	23592263
MIRT1072446	hsa-miR-1262	CLIP-seq
MIRT1072447	hsa-miR-1283	CLIP-seq
MIRT1072448	hsa-miR-1293	CLIP-seq
MIRT1072449	hsa-miR-135a	CLIP-seq
MIRT1072450	hsa-miR-135b	CLIP-seq
MIRT1072451	hsa-miR-1827	CLIP-seq
MIRT1072452	hsa-miR-186	CLIP-seq
MIRT1072453	hsa-miR-216b	CLIP-seq
MIRT1072454	hsa-miR-221	CLIP-seq
MIRT1072455	hsa-miR-222	CLIP-seq
MIRT1072456	hsa-miR-3119	CLIP-seq
MIRT1072457	hsa-miR-3126-5p	CLIP-seq
MIRT1072458	hsa-miR-3129-3p	CLIP-seq
MIRT1072459	hsa-miR-3133	CLIP-seq
MIRT1072460	hsa-miR-3148	CLIP-seq
MIRT1072461	hsa-miR-3163	CLIP-seq
MIRT1072462	hsa-miR-3173-3p	CLIP-seq
MIRT1072463	hsa-miR-3185	CLIP-seq
MIRT1072464	hsa-miR-3658	CLIP-seq
MIRT1072465	hsa-miR-3675-3p	CLIP-seq
MIRT1072466	hsa-miR-3681	CLIP-seq
MIRT1072467	hsa-miR-4316	CLIP-seq
MIRT1072468	hsa-miR-4419a	CLIP-seq
MIRT1072469	hsa-miR-4428	CLIP-seq
MIRT1072470	hsa-miR-4483	CLIP-seq
MIRT1072471	hsa-miR-4504	CLIP-seq
MIRT1072472	hsa-miR-4510	CLIP-seq
MIRT1072473	hsa-miR-4521	CLIP-seq
MIRT1072474	hsa-miR-4663	CLIP-seq
MIRT1072475	hsa-miR-4684-3p	CLIP-seq
MIRT1072476	hsa-miR-4684-5p	CLIP-seq
MIRT1072477	hsa-miR-4701-3p	CLIP-seq
MIRT1072478	hsa-miR-4709-3p	CLIP-seq
MIRT1072479	hsa-miR-4717-5p	CLIP-seq
MIRT1072480	hsa-miR-4719	CLIP-seq
MIRT1072481	hsa-miR-4728-3p	CLIP-seq
MIRT1072482	hsa-miR-513c	CLIP-seq
MIRT1072483	hsa-miR-514b-5p	CLIP-seq
MIRT1072484	hsa-miR-548c-3p	CLIP-seq
MIRT1072485	hsa-miR-548v	CLIP-seq
MIRT1072486	hsa-miR-549	CLIP-seq
MIRT1072487	hsa-miR-568	CLIP-seq
MIRT1072488	hsa-miR-873	CLIP-seq
MIRT1072447	hsa-miR-1283	CLIP-seq
MIRT1072454	hsa-miR-221	CLIP-seq
MIRT1072455	hsa-miR-222	CLIP-seq
MIRT1072485	hsa-miR-548v	CLIP-seq
MIRT1072452	hsa-miR-186	CLIP-seq
MIRT1072457	hsa-miR-3126-5p	CLIP-seq
MIRT1072462	hsa-miR-3173-3p	CLIP-seq
MIRT2017865	hsa-miR-3606	CLIP-seq
MIRT2017866	hsa-miR-3689a-3p	CLIP-seq
MIRT2017867	hsa-miR-3689c	CLIP-seq
MIRT2017868	hsa-miR-3973	CLIP-seq
MIRT2017869	hsa-miR-4266	CLIP-seq
MIRT2017870	hsa-miR-4330	CLIP-seq
MIRT1072468	hsa-miR-4419a	CLIP-seq
MIRT2017871	hsa-miR-4425	CLIP-seq
MIRT1072469	hsa-miR-4428	CLIP-seq
MIRT1072472	hsa-miR-4510	CLIP-seq
MIRT1072473	hsa-miR-4521	CLIP-seq
MIRT1072474	hsa-miR-4663	CLIP-seq
MIRT2017872	hsa-miR-4694-3p	CLIP-seq
MIRT1072481	hsa-miR-4728-3p	CLIP-seq
MIRT2017873	hsa-miR-4766-3p	CLIP-seq
MIRT2017874	hsa-miR-520g	CLIP-seq
MIRT2017875	hsa-miR-520h	CLIP-seq
MIRT2017876	hsa-miR-539	CLIP-seq
MIRT2017877	hsa-miR-651	CLIP-seq
MIRT1072488	hsa-miR-873	CLIP-seq
MIRT2017878	hsa-miR-921	CLIP-seq
MIRT2249685	hsa-miR-1224-5p	CLIP-seq
MIRT2249686	hsa-miR-1233	CLIP-seq
MIRT1072452	hsa-miR-186	CLIP-seq
MIRT2249687	hsa-miR-1976	CLIP-seq
MIRT1072453	hsa-miR-216b	CLIP-seq
MIRT1072465	hsa-miR-3675-3p	CLIP-seq
MIRT2017868	hsa-miR-3973	CLIP-seq
MIRT2249688	hsa-miR-4279	CLIP-seq
MIRT2249689	hsa-miR-4422	CLIP-seq
MIRT2249690	hsa-miR-4643	CLIP-seq
MIRT2249691	hsa-miR-466	CLIP-seq
MIRT1072475	hsa-miR-4684-3p	CLIP-seq
MIRT1072476	hsa-miR-4684-5p	CLIP-seq
MIRT2249692	hsa-miR-4751	CLIP-seq
MIRT2249693	hsa-miR-4789-3p	CLIP-seq
MIRT2249694	hsa-miR-486-5p	CLIP-seq
MIRT2249695	hsa-miR-501-3p	CLIP-seq
MIRT2249696	hsa-miR-502-3p	CLIP-seq
MIRT2017874	hsa-miR-520g	CLIP-seq
MIRT2017875	hsa-miR-520h	CLIP-seq
MIRT1072486	hsa-miR-549	CLIP-seq
MIRT2249697	hsa-miR-590-3p	CLIP-seq
MIRT1072447	hsa-miR-1283	CLIP-seq
MIRT2389476	hsa-miR-1305	CLIP-seq
MIRT1072452	hsa-miR-186	CLIP-seq
MIRT1072454	hsa-miR-221	CLIP-seq
MIRT1072455	hsa-miR-222	CLIP-seq
MIRT1072457	hsa-miR-3126-5p	CLIP-seq
MIRT1072459	hsa-miR-3133	CLIP-seq
MIRT1072468	hsa-miR-4419a	CLIP-seq
MIRT1072472	hsa-miR-4510	CLIP-seq
MIRT1072474	hsa-miR-4663	CLIP-seq
MIRT1072481	hsa-miR-4728-3p	CLIP-seq
MIRT2389477	hsa-miR-498	CLIP-seq
MIRT1072485	hsa-miR-548v	CLIP-seq
MIRT2389478	hsa-miR-607	CLIP-seq
MIRT1072484	hsa-miR-548c-3p	CLIP-seq
MIRT1072487	hsa-miR-568	CLIP-seq
MIRT2553136	hsa-miR-1234	CLIP-seq
MIRT1072446	hsa-miR-1262	CLIP-seq
MIRT1072448	hsa-miR-1293	CLIP-seq
MIRT1072449	hsa-miR-135a	CLIP-seq
MIRT1072450	hsa-miR-135b	CLIP-seq
MIRT2553137	hsa-miR-2114	CLIP-seq
MIRT2553138	hsa-miR-2964a-5p	CLIP-seq
MIRT2553139	hsa-miR-300	CLIP-seq
MIRT2553140	hsa-miR-3123	CLIP-seq
MIRT1072458	hsa-miR-3129-3p	CLIP-seq
MIRT1072460	hsa-miR-3148	CLIP-seq
MIRT2553141	hsa-miR-3162-3p	CLIP-seq
MIRT1072461	hsa-miR-3163	CLIP-seq
MIRT2553142	hsa-miR-3616-3p	CLIP-seq
MIRT2553143	hsa-miR-3646	CLIP-seq
MIRT2553144	hsa-miR-381	CLIP-seq
MIRT2553145	hsa-miR-3925-5p	CLIP-seq
MIRT2553146	hsa-miR-3976	CLIP-seq
MIRT2553147	hsa-miR-4257	CLIP-seq
MIRT2553148	hsa-miR-4274	CLIP-seq
MIRT2553149	hsa-miR-4421	CLIP-seq
MIRT2553150	hsa-miR-4436b-3p	CLIP-seq
MIRT1072470	hsa-miR-4483	CLIP-seq
MIRT2553151	hsa-miR-4530	CLIP-seq
MIRT2553152	hsa-miR-4652-3p	CLIP-seq
MIRT1072477	hsa-miR-4701-3p	CLIP-seq
MIRT2553153	hsa-miR-4704-3p	CLIP-seq
MIRT2553154	hsa-miR-4707-5p	CLIP-seq
MIRT2553155	hsa-miR-4738-3p	CLIP-seq
MIRT2553156	hsa-miR-4765	CLIP-seq
MIRT2553157	hsa-miR-4799-5p	CLIP-seq
MIRT2249695	hsa-miR-501-3p	CLIP-seq
MIRT2249696	hsa-miR-502-3p	CLIP-seq
MIRT1072484	hsa-miR-548c-3p	CLIP-seq
MIRT1072487	hsa-miR-568	CLIP-seq
MIRT2553158	hsa-miR-582-3p	CLIP-seq
MIRT2553159	hsa-miR-592	CLIP-seq
MIRT2553160	hsa-miR-597	CLIP-seq
MIRT2553161	hsa-miR-624	CLIP-seq
MIRT2553162	hsa-miR-634	CLIP-seq
MIRT2553163	hsa-miR-640	CLIP-seq
MIRT2553164	hsa-miR-767-5p	CLIP-seq
MIRT2553165	hsa-miR-769-5p	CLIP-seq
MIRT2249686	hsa-miR-1233	CLIP-seq
MIRT2553136	hsa-miR-1234	CLIP-seq
MIRT1072446	hsa-miR-1262	CLIP-seq
MIRT1072448	hsa-miR-1293	CLIP-seq
MIRT1072449	hsa-miR-135a	CLIP-seq
MIRT1072450	hsa-miR-135b	CLIP-seq
MIRT2553137	hsa-miR-2114	CLIP-seq
MIRT2553139	hsa-miR-300	CLIP-seq
MIRT1072458	hsa-miR-3129-3p	CLIP-seq
MIRT1072460	hsa-miR-3148	CLIP-seq
MIRT2553141	hsa-miR-3162-3p	CLIP-seq
MIRT1072461	hsa-miR-3163	CLIP-seq
MIRT2553142	hsa-miR-3616-3p	CLIP-seq
MIRT2553143	hsa-miR-3646	CLIP-seq
MIRT2682918	hsa-miR-3688-5p	CLIP-seq
MIRT2553144	hsa-miR-381	CLIP-seq
MIRT2553147	hsa-miR-4257	CLIP-seq
MIRT2553148	hsa-miR-4274	CLIP-seq
MIRT2553150	hsa-miR-4436b-3p	CLIP-seq
MIRT2682919	hsa-miR-4470	CLIP-seq
MIRT1072470	hsa-miR-4483	CLIP-seq
MIRT2553151	hsa-miR-4530	CLIP-seq
MIRT2553152	hsa-miR-4652-3p	CLIP-seq
MIRT2017872	hsa-miR-4694-3p	CLIP-seq
MIRT1072477	hsa-miR-4701-3p	CLIP-seq
MIRT2553153	hsa-miR-4704-3p	CLIP-seq
MIRT2553154	hsa-miR-4707-5p	CLIP-seq
MIRT2553155	hsa-miR-4738-3p	CLIP-seq
MIRT2553156	hsa-miR-4765	CLIP-seq
MIRT2553157	hsa-miR-4799-5p	CLIP-seq
MIRT2249695	hsa-miR-501-3p	CLIP-seq
MIRT2249696	hsa-miR-502-3p	CLIP-seq
MIRT2682920	hsa-miR-548a-3p	CLIP-seq
MIRT1072484	hsa-miR-548c-3p	CLIP-seq
MIRT2682921	hsa-miR-548e	CLIP-seq
MIRT2682922	hsa-miR-548f	CLIP-seq
MIRT1072487	hsa-miR-568	CLIP-seq
MIRT2553158	hsa-miR-582-3p	CLIP-seq
MIRT2553159	hsa-miR-592	CLIP-seq
MIRT2553160	hsa-miR-597	CLIP-seq
MIRT2553161	hsa-miR-624	CLIP-seq
MIRT2553162	hsa-miR-634	CLIP-seq
MIRT2553163	hsa-miR-640	CLIP-seq
MIRT2553164	hsa-miR-767-5p	CLIP-seq
MIRT2553165	hsa-miR-769-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25347204, 33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IEA
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0016226	Process	Iron-sulfur cluster assembly	IBA
GO:0016226	Process	Iron-sulfur cluster assembly	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051536	Function	Iron-sulfur cluster binding	IEA
GO:0051537	Function	2 iron, 2 sulfur cluster binding	IBA
GO:0051604	Process	Protein maturation	IBA
GO:0120510	Component	Mitochondrial [4Fe-4S] assembly complex	IDA	25347204

Other IDs

• MIM: 611006
• HGNC: 28660
• e!Ensembl: ENSG00000135070

Protein

• UniProt ID: Q9BUE6
• Protein name: Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (hIscA)
• Protein function: Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. {ECO:0000269|PubMed:15262227, ECO:0000269|Pub
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01521	Fe-S_biosyn	23 → 125	Iron-sulphur cluster biosynthesis	Family

• Tissue specificity: TISSUE SPECIFICITY: Detected in cerebellum, kidney and heart. {ECO:0000269|PubMed:15262227}.
• Sequence:

  MSASLVRATVRAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL
  SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSEFVFNNPNIKGT
  CGCGESFNI

• Sequence length: 129

Pathways

Reactome Pathway:

Mitochondrial iron-sulfur cluster biogenesis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Multiple mitochondrial dysfunctions syndrome 5	Pathogenic	rs1587823007	RCV000857321	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Fatal multiple mitochondrial dysfunctions syndrome	Conflicting classifications of pathogenicity	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ISCA1-related disorder	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (18)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinogenesis	Carcinogenesis	Pubtator	36072584	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	36385109	Associate	★☆☆☆☆ Found in Text Mining only
Developmental regression	Developmental regression	HPO_DG			★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★☆☆☆☆ Found in Text Mining only
Leukodystrophy	Leukodystrophy	CLINVAR_DG	28356563		★☆☆☆☆ Found in Text Mining only
Leukodystrophy	Leukodystrophy	BEFREE	29767723		★☆☆☆☆ Found in Text Mining only
Leukodystrophy	Leukodystrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial disease	Pubtator	28356563	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Mitochondrial Dysfunctions Syndrome	Multiple Mitochondrial Dysfunctions Syndrome	BEFREE	28356563		★☆☆☆☆ Found in Text Mining only
Multiple Mitochondrial Dysfunctions Syndrome	Multiple Mitochondrial Dysfunctions Syndrome	CLINVAR_DG	28356563		★☆☆☆☆ Found in Text Mining only
MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME 5	Multiple Mitochondrial Dysfunctions Syndrome	CLINVAR_DG	28356563, 30105122		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME 5	Multiple Mitochondrial Dysfunctions Syndrome	UNIPROT_DG	28356563		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME 5	Multiple Mitochondrial Dysfunctions Syndrome	GENOMICS_ENGLAND_DG	28356563, 29767723		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Multiple mitochondrial dysfunctions syndrome type 5	Multiple Mitochondrial Dysfunctions Syndrome	Orphanet			★☆☆☆☆ Found in Text Mining only
Pachygyria	Pachygyria	CLINVAR_DG	28356563		★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	39766805	Associate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	36072584	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for ISCA1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ISCA1.