INTS15 (integrator complex subunit 15)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 79034
• Gene name: Integrator complex subunit 15
• Gene symbol: INTS15
• Synonyms (NCBI Gene): C7orf26
• Chromosome: 7
• Chromosome location: 7p22.1

miRNA Show/Hide all (65)

miRTarBase ID	miRNA	Experiments	Reference
MIRT041344	hsa-miR-193b-3p	CLASH	23622248
MIRT569566	hsa-miR-6768-5p	PAR-CLIP	20371350
MIRT569565	hsa-miR-4438	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569564	hsa-miR-216b-3p	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569562	hsa-miR-7974	PAR-CLIP	20371350
MIRT569560	hsa-miR-6788-3p	PAR-CLIP	20371350
MIRT569566	hsa-miR-6768-5p	PAR-CLIP	20371350
MIRT569565	hsa-miR-4438	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569564	hsa-miR-216b-3p	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569562	hsa-miR-7974	PAR-CLIP	20371350
MIRT569561	hsa-miR-4711-3p	PAR-CLIP	20371350
MIRT569560	hsa-miR-6788-3p	PAR-CLIP	20371350
MIRT569566	hsa-miR-6768-5p	PAR-CLIP	20371350
MIRT569565	hsa-miR-4438	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569564	hsa-miR-216b-3p	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569562	hsa-miR-7974	PAR-CLIP	20371350
MIRT569560	hsa-miR-6788-3p	PAR-CLIP	20371350
MIRT569566	hsa-miR-6768-5p	PAR-CLIP	20371350
MIRT569565	hsa-miR-4438	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569564	hsa-miR-216b-3p	PAR-CLIP	20371350
MIRT569563	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT569562	hsa-miR-7974	PAR-CLIP	20371350
MIRT569561	hsa-miR-4711-3p	PAR-CLIP	20371350
MIRT569560	hsa-miR-6788-3p	PAR-CLIP	20371350
MIRT852136	hsa-miR-1915	CLIP-seq
MIRT852137	hsa-miR-203	CLIP-seq
MIRT852138	hsa-miR-24	CLIP-seq
MIRT852139	hsa-miR-2467-5p	CLIP-seq
MIRT852140	hsa-miR-298	CLIP-seq
MIRT852141	hsa-miR-3158-5p	CLIP-seq
MIRT852142	hsa-miR-378g	CLIP-seq
MIRT852143	hsa-miR-3919	CLIP-seq
MIRT852144	hsa-miR-3925-5p	CLIP-seq
MIRT852145	hsa-miR-4282	CLIP-seq
MIRT852146	hsa-miR-4304	CLIP-seq
MIRT852147	hsa-miR-4437	CLIP-seq
MIRT852148	hsa-miR-4508	CLIP-seq
MIRT852149	hsa-miR-4674	CLIP-seq
MIRT852150	hsa-miR-4726-3p	CLIP-seq
MIRT852151	hsa-miR-4773	CLIP-seq
MIRT852152	hsa-miR-661	CLIP-seq
MIRT1952772	hsa-miR-125a-5p	CLIP-seq
MIRT1952773	hsa-miR-125b	CLIP-seq
MIRT1952774	hsa-miR-1908	CLIP-seq
MIRT1952775	hsa-miR-4319	CLIP-seq
MIRT1952776	hsa-miR-4468	CLIP-seq
MIRT1952777	hsa-miR-4519	CLIP-seq
MIRT1952778	hsa-miR-4706	CLIP-seq
MIRT1952779	hsa-miR-4732-3p	CLIP-seq
MIRT1952780	hsa-miR-4749-5p	CLIP-seq
MIRT1952781	hsa-miR-512-3p	CLIP-seq
MIRT1952782	hsa-miR-663	CLIP-seq
MIRT1952783	hsa-miR-670	CLIP-seq
MIRT852138	hsa-miR-24	CLIP-seq
MIRT852142	hsa-miR-378g	CLIP-seq
MIRT852147	hsa-miR-4437	CLIP-seq
MIRT852149	hsa-miR-4674	CLIP-seq
MIRT852152	hsa-miR-661	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IEA
GO:0001654	Process	Eye development	IEA
GO:0005634	Component	Nucleus	IDA	36920904, 39032490
GO:0005634	Component	Nucleus	IEA
GO:0005694	Component	Chromosome	IDA	36920904
GO:0005694	Component	Chromosome	IEA
GO:0007420	Process	Brain development	IEA
GO:0032039	Component	Integrator complex	IBA
GO:0032039	Component	Integrator complex	IDA	33973408, 36920904, 38823386, 39032490
GO:0160232	Component	INTAC complex	IDA	38570683
GO:0160240	Process	RNA polymerase II transcription initiation surveillance	IDA	36920904, 38570683

Other IDs

• MIM: 621239
• HGNC: 21702
• e!Ensembl: ENSG00000146576

Protein

• UniProt ID: Q96N11
• Protein name: Integrator complex subunit 15
• Protein function: Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:36920904, PubMed:38570683, PubMed:38823386). The integrator complex provides a
• PDB: 8RBX , 8RBZ , 8RC4 , 9EOF , 9EP1 , 9EP4 , 9FA4 , 9FA7
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14964	DUF4507	2 → 381	Domain of unknown function (DUF4507)	Family

• Sequence:

  MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPIVDKGPVELLEEFVFQVPKERS
  AQPKRLNSLQELQLLEIMCNYFQEQTKDSVRQIIFSSLFSPQGNKADDSRMSLLGKLVSM
  AVAVCRIPVLECAASWLQRTPVVYCVRLAKALVDDYCCLVPGSIQTLKQIFSASPRFCCQ
  FITSVTALYDLSSDDLIPPMDLLEMIVTWIFEDPRLILITFLNTPIAANLPIGFLELTPL
  VGLIRWCVKAPLAYKRKKKPPLSNGHVSNKVTKDPGVGMDRDSHLLYSKLHLSVLQVLMT
  LQLHLTEKNLYGRLGLILFDHMVPLVEEINRLADELNPLNASQEIELSLDRLAQALQVAM
  ASGALLCTRDDLRTLCSRLPHNNLLQLVISGPVQQSPHAALPPGFYPHIHTPPLGYGAVP
  AHPAAHPALPTHPGHTFISGVTFPFRPIR

• Sequence length: 449

Related Genes

No strongly related genes found yet for INTS15.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to INTS15.