IGHV1-46 (immunoglobulin heavy variable 1-46)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 28465 |
| Gene name | Immunoglobulin heavy variable 1-46 |
| Gene symbol | IGHV1-46 |
| Synonyms (NCBI Gene) |
IGHV146
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| Chromosome | 14 |
| Chromosome location | 14q32.33 |
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P01743 | ||||||||||
| Protein name | Immunoglobulin heavy variable 1-46 (Ig heavy chain V-I region DOT) (Ig heavy chain V-I region HG3) (Ig heavy chain V-I region Mot) | ||||||||||
| Protein function | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MDWTWRVFCLLAVAPGAHSQVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAP |
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| Sequence length | 117 | ||||||||||
| Interactions | View interactions | ||||||||||
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Related Genes
Genes most often co-reported with IGHV1-46 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to IGHV1-46 (see Related Genes above), that are NOT already directly curated for IGHV1-46 itself -- a lead worth checking, not a confirmed association.
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