IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker))

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Gene Gene information from NCBI Gene database.
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Entrez ID 3502
Gene name Immunoglobulin heavy constant gamma 3 (G3m marker)
Gene symbol IGHG3
Synonyms (NCBI Gene)
IgG3
Chromosome 14
Chromosome location 14q32.33
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20 Show/Hide all (20)
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GO ID Ontology Definition Evidence Reference
GO:0002250 Process Adaptive immune response IEA
GO:0002250 Process Adaptive immune response NAS 20176268
GO:0002376 Process Immune system process IEA
GO:0003823 Function Antigen binding IBA
GO:0005576 Component Extracellular region IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
147120 5527 ENSG00000211897
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P01860
Protein name Immunoglobulin heavy constant gamma 3 (HDC) (Heavy chain disease protein) (Ig gamma-3 chain C region)
Protein function Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins s
PDB 4WWI , 4ZNC , 5M3V , 5W38 , 6D58 , 6G1E
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07654 C1-set 278 → 362 Immunoglobulin C1-set domain Domain
PF07654 C1-set 170 → 258 Immunoglobulin C1-set domain Domain
PF07654 C1-set 8 → 90 Immunoglobulin C1-set domain Domain
Sequence 
ASTKGPSVFPLAPCSRSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSS
GLYSLSSVVTVPSSSLGTQTYTCNVNHKPSNTKVDKRVELKTPLGDTTHTCPRCPEPKSC
DTPPPCPRCPEPKSCDTPPPCPRCPEPKSCDTPPPCPRCPAPELLGGPSVFLFPPKPKDT
LMISRTPEVTCVVVDVSHEDPEVQFKWYVDGVEVHNAKTKPREEQYNSTFRVVSVLTVLH
QDWLNGKEYKCKVSNKALPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVK
GFYPSDIAVEWESSGQPENNYNTTPPMLDSDGSFFLYSKLTVDKSRWQQGNIFSCSVMHE
ALHNRFTQKSLSLSPGK
Sequence length 377
Interactions View interactions

No strongly related genes found yet for IGHG3.

No additional diseases found yet through genes similar to IGHG3.