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Gene Gene information from NCBI Gene database.
Entrez ID 9543
Gene name Immunoglobulin superfamily DCC subclass member 3
Gene symbol IGDCC3
Synonyms (NCBI Gene)
HsT18880PUNC
Chromosome 15
Chromosome location 15q22.31
miRNA miRNA information provided by mirtarbase database.
356 Show/Hide all (356)
miRTarBase ID miRNA Experiments Reference
MIRT044339 hsa-miR-106b-5p CLASH 23622248
MIRT710752 hsa-miR-6729-3p HITS-CLIP 19536157
MIRT710753 hsa-miR-6072 HITS-CLIP 19536157
MIRT710751 hsa-miR-6891-3p HITS-CLIP 19536157
MIRT710750 hsa-miR-324-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
3
GO ID Ontology Definition Evidence Reference
GO:0016020 Component Membrane IEA
GO:0050885 Process Neuromuscular process controlling balance IEA
GO:0098609 Process Cell-cell adhesion IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604184 9700 ENSG00000174498
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IVU1
Protein name Immunoglobulin superfamily DCC subclass member 3 (Putative neuronal cell adhesion molecule)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00041 fn3 425 → 510 Fibronectin type III domain Domain
PF00041 fn3 522 → 606 Fibronectin type III domain Domain
PF07679 I-set 330 → 417 Immunoglobulin I-set domain Domain
PF07679 I-set 139 → 227 Immunoglobulin I-set domain Domain
PF13927 Ig_3 44 → 121 Domain
PF13927 Ig_3 237 → 310 Domain
Sequence
Sequence length 814
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
Acute myeloid leukemia Likely benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder Uncertain significance ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Breast Carcinoma Breast Carcinoma BEFREE 18044827
★★★★★
★☆☆☆☆
Found in Text Mining only
Colorectal Carcinoma Colorectal Cancer BEFREE 27049830
★★★★★
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 27049830 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of breast Breast Cancer BEFREE 18044827
★★★★★
★☆☆☆☆
Found in Text Mining only