IFT46 (intraflagellar transport 46)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 56912
• Gene name: Intraflagellar transport 46
• Gene symbol: IFT46
• Synonyms (NCBI Gene): C11orf2, C11orf60, CFAP32, FAP32
• Chromosome: 11
• Chromosome location: 11q23.3

miRNA Show/Hide all (91)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019794	hsa-miR-375	Microarray	20215506
MIRT617498	hsa-miR-6750-3p	HITS-CLIP	23824327
MIRT617497	hsa-miR-4330	HITS-CLIP	23824327
MIRT617498	hsa-miR-6750-3p	HITS-CLIP	23824327
MIRT617497	hsa-miR-4330	HITS-CLIP	23824327
MIRT1061036	hsa-miR-128	CLIP-seq
MIRT1061037	hsa-miR-1827	CLIP-seq
MIRT1061038	hsa-miR-3120-3p	CLIP-seq
MIRT1061039	hsa-miR-3200-5p	CLIP-seq
MIRT1061040	hsa-miR-3935	CLIP-seq
MIRT1061041	hsa-miR-4453	CLIP-seq
MIRT1061042	hsa-miR-4514	CLIP-seq
MIRT1061043	hsa-miR-4532	CLIP-seq
MIRT1061044	hsa-miR-4538	CLIP-seq
MIRT1061045	hsa-miR-4649-3p	CLIP-seq
MIRT1061046	hsa-miR-4692	CLIP-seq
MIRT1061047	hsa-miR-4707-5p	CLIP-seq
MIRT1061048	hsa-miR-4736	CLIP-seq
MIRT1061049	hsa-miR-4747-5p	CLIP-seq
MIRT1061050	hsa-miR-4764-3p	CLIP-seq
MIRT1061051	hsa-miR-494	CLIP-seq
MIRT1061052	hsa-miR-586	CLIP-seq
MIRT1061053	hsa-miR-646	CLIP-seq
MIRT1061054	hsa-miR-657	CLIP-seq
MIRT1061055	hsa-miR-940	CLIP-seq
MIRT1061041	hsa-miR-4453	CLIP-seq
MIRT1061044	hsa-miR-4538	CLIP-seq
MIRT1061049	hsa-miR-4747-5p	CLIP-seq
MIRT1061051	hsa-miR-494	CLIP-seq
MIRT1061053	hsa-miR-646	CLIP-seq
MIRT1061037	hsa-miR-1827	CLIP-seq
MIRT1061038	hsa-miR-3120-3p	CLIP-seq
MIRT1061039	hsa-miR-3200-5p	CLIP-seq
MIRT1061040	hsa-miR-3935	CLIP-seq
MIRT1061043	hsa-miR-4532	CLIP-seq
MIRT1061045	hsa-miR-4649-3p	CLIP-seq
MIRT1061047	hsa-miR-4707-5p	CLIP-seq
MIRT1061050	hsa-miR-4764-3p	CLIP-seq
MIRT1061052	hsa-miR-586	CLIP-seq
MIRT1061055	hsa-miR-940	CLIP-seq
MIRT2246473	hsa-miR-1297	CLIP-seq
MIRT2246474	hsa-miR-26a	CLIP-seq
MIRT2246475	hsa-miR-26b	CLIP-seq
MIRT2246476	hsa-miR-3622b-5p	CLIP-seq
MIRT2246477	hsa-miR-3688-5p	CLIP-seq
MIRT2246478	hsa-miR-3913-3p	CLIP-seq
MIRT2246479	hsa-miR-4465	CLIP-seq
MIRT2246480	hsa-miR-562	CLIP-seq
MIRT2549996	hsa-miR-1207-3p	CLIP-seq
MIRT2549997	hsa-miR-125a-5p	CLIP-seq
MIRT2549998	hsa-miR-125b	CLIP-seq
MIRT2549999	hsa-miR-2467-3p	CLIP-seq
MIRT2550000	hsa-miR-3184	CLIP-seq
MIRT2246476	hsa-miR-3622b-5p	CLIP-seq
MIRT2246477	hsa-miR-3688-5p	CLIP-seq
MIRT2246478	hsa-miR-3913-3p	CLIP-seq
MIRT2550001	hsa-miR-423-5p	CLIP-seq
MIRT2550002	hsa-miR-4267	CLIP-seq
MIRT2550003	hsa-miR-4319	CLIP-seq
MIRT1061041	hsa-miR-4453	CLIP-seq
MIRT1061044	hsa-miR-4538	CLIP-seq
MIRT2550004	hsa-miR-4640-5p	CLIP-seq
MIRT2550005	hsa-miR-4726-5p	CLIP-seq
MIRT2550006	hsa-miR-4731-5p	CLIP-seq
MIRT1061049	hsa-miR-4747-5p	CLIP-seq
MIRT2550007	hsa-miR-4749-3p	CLIP-seq
MIRT2550008	hsa-miR-486-3p	CLIP-seq
MIRT1061051	hsa-miR-494	CLIP-seq
MIRT2550009	hsa-miR-549	CLIP-seq
MIRT1061053	hsa-miR-646	CLIP-seq
MIRT2549996	hsa-miR-1207-3p	CLIP-seq
MIRT2549997	hsa-miR-125a-5p	CLIP-seq
MIRT2549998	hsa-miR-125b	CLIP-seq
MIRT2549999	hsa-miR-2467-3p	CLIP-seq
MIRT2550000	hsa-miR-3184	CLIP-seq
MIRT2246476	hsa-miR-3622b-5p	CLIP-seq
MIRT2246477	hsa-miR-3688-5p	CLIP-seq
MIRT2550001	hsa-miR-423-5p	CLIP-seq
MIRT2550002	hsa-miR-4267	CLIP-seq
MIRT2550003	hsa-miR-4319	CLIP-seq
MIRT1061041	hsa-miR-4453	CLIP-seq
MIRT1061044	hsa-miR-4538	CLIP-seq
MIRT2550004	hsa-miR-4640-5p	CLIP-seq
MIRT2550005	hsa-miR-4726-5p	CLIP-seq
MIRT2550006	hsa-miR-4731-5p	CLIP-seq
MIRT1061049	hsa-miR-4747-5p	CLIP-seq
MIRT2550007	hsa-miR-4749-3p	CLIP-seq
MIRT2550008	hsa-miR-486-3p	CLIP-seq
MIRT1061051	hsa-miR-494	CLIP-seq
MIRT2550009	hsa-miR-549	CLIP-seq
MIRT1061053	hsa-miR-646	CLIP-seq

Gene ontology (GO) Show/Hide all (30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	ISS
GO:0005737	Component	Cytoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IEA
GO:0005815	Component	Microtubule organizing center	IBA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005929	Component	Cilium	IEA
GO:0005929	Component	Cilium	NAS	26980730
GO:0005929	Component	Cilium	TAS
GO:0007224	Process	Smoothened signaling pathway	IEA
GO:0030992	Component	Intraciliary transport particle B	IBA
GO:0030992	Component	Intraciliary transport particle B	IEA
GO:0030992	Component	Intraciliary transport particle B	IPI	26980730
GO:0030992	Component	Intraciliary transport particle B	ISS
GO:0031514	Component	Motile cilium	IBA
GO:0031514	Component	Motile cilium	IEA
GO:0031514	Component	Motile cilium	ISS
GO:0035720	Process	Intraciliary anterograde transport	NAS	26980730
GO:0036064	Component	Ciliary basal body	ISS
GO:0042073	Process	Intraciliary transport	IBA
GO:0042073	Process	Intraciliary transport	IEA
GO:0042073	Process	Intraciliary transport	ISS
GO:0042995	Component	Cell projection	IEA
GO:0050821	Process	Protein stabilization	ISS
GO:0060271	Process	Cilium assembly	IBA
GO:0060271	Process	Cilium assembly	IEA
GO:0060271	Process	Cilium assembly	ISS
GO:0060271	Process	Cilium assembly	NAS	26980730
GO:0097542	Component	Ciliary tip	TAS
GO:0120025	Component	Plasma membrane bounded cell projection	IEA

Other IDs

• MIM: 620506
• HGNC: 26146
• e!Ensembl: ENSG00000118096

Protein

• UniProt ID: Q9NQC8
• Protein name: Intraflagellar transport protein 46 homolog
• Protein function: Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (B
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12317	IFT46_B_C	63 → 273	Intraflagellar transport complex B protein 46 C terminal	Family

• Sequence:

  MADNSSDECEEENNKEKKKTSQLTPQRGFSENEDDDDDDDDSSETDSDSDDDDEEHGAPL
  EGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVP
  RPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNITQHMKVKSLEDAEKNPKAID
  TWIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLAEYI
  DMICAILDIPVYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPSSNSTSQAGDMET
  LTFS

• Sequence length: 304

Pathways

Reactome Pathway:

Intraflagellar transport

Related Genes

No strongly related genes found yet for IFT46.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to IFT46.