IFNA1 (interferon alpha 1)

Gene Gene information from NCBI Gene database.
Gene SNPs Transcription factors Other IDs Associated diseases
Entrez ID 3439
Gene name Interferon alpha 1
Gene symbol IFNA1
Synonyms (NCBI Gene)
IFLIFNIFN-ALPHAIFN-alphaDIFNA13IFNA@leIF D
Chromosome 9
Chromosome location 9p21.3
Summary This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral,
miRNA miRNA information provided by mirtarbase database.
6
Gene SNPs Transcription factors Other IDs Associated diseases
Show/Hide all (6)
miRTarBase ID miRNA Experiments Reference
MIRT023373 hsa-miR-122-5p Microarray 17612493
MIRT736415 hsa-miR-491-3p qRT-PCRFlow cytometry 33679688
MIRT1060624 hsa-miR-219-2-3p CLIP-seq
MIRT1060625 hsa-miR-4535 CLIP-seq
MIRT1060626 hsa-miR-4776-5p CLIP-seq
Transcription factors Transcription factors information provided by TRRUST V2 database.
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Gene SNPs Transcription factors Other IDs Associated diseases
Show/Hide all (17)
Transcription factor Regulation Reference
BRCA1 Activation 17374731
HDAC3 Repression 22685561
IRF1 Activation 12077266
IRF1 Unknown 7606736
IRF3 Activation 12242290
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Gene SNPs Transcription factors Other IDs Associated diseases
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GO ID Ontology Definition Evidence Reference
GO:0002250 Process Adaptive immune response IBA
GO:0002286 Process T cell activation involved in immune response IBA
GO:0002312 Process B cell activation involved in immune response IBA
GO:0002323 Process Natural killer cell activation involved in immune response IBA
GO:0005125 Function Cytokine activity IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene SNPs Transcription factors Other IDs Associated diseases
MIM HGNC e!Ensembl
147660 5417 ENSG00000197919
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Gene SNPs Transcription factors Other IDs Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (16)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
BIPOLAR DISORDER — Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CARCINOMA, HEPATOCELLULAR — CTD
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
COLORECTAL NEOPLASMS — CTD
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HEMORRHAGIC FEVER, CRIMEAN — Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (628)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acquired Hypogammaglobulinemia Common Variable Immunodeficiency BEFREE 22048980
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute Coronary Syndrome Coronary Syndrome BEFREE 20177960, 25997853
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute encephalopathy with biphasic seizures and late reduced diffusion Encephalopathy With Biphasic Seizures And Diffusion BEFREE 29725488
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute intermittent porphyria Intermittent Porphyria BEFREE 28373582, 31287532
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute leukemia Leukemia BEFREE 10535471, 28457953, 8003558
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute lymphocytic leukemia Lymphocytic Leukemia BEFREE 10637472, 1562733, 1701354, 1886420, 7505146, 8003558, 8100807
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute pancreatitis Pancreatitis BEFREE 19246919, 30061072
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma Adenocarcinoma BEFREE 10697627, 7775254
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma Adenocarcinoma CTD_human_DG 17198089
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of colon Adenocarcinoma Of Colon BEFREE 1893380
★★★★★
★☆☆☆☆
Found in Text Mining only