IFI27L1 (interferon alpha inducible protein 27 like 1)

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Gene Gene information from NCBI Gene database.
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Entrez ID 122509
Gene name Interferon alpha inducible protein 27 like 1
Gene symbol IFI27L1
Synonyms (NCBI Gene)
FAM14BISG12C
Chromosome 14
Chromosome location 14q32.12
miRNA miRNA information provided by mirtarbase database.
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miRTarBase ID miRNA Experiments Reference
MIRT1060195 hsa-miR-219-5p CLIP-seq
MIRT1060196 hsa-miR-2355-3p CLIP-seq
MIRT1060197 hsa-miR-3121-5p CLIP-seq
MIRT1060198 hsa-miR-4699-5p CLIP-seq
MIRT1060199 hsa-miR-4782-3p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0006915 Process Apoptotic process IEA
GO:0006915 Process Apoptotic process IMP 27673746
GO:0016020 Component Membrane IEA
GO:0031966 Component Mitochondrial membrane IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
611320 19754 ENSG00000165948
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96BM0
Protein name Interferon alpha-inducible protein 27-like protein 1 (Interferon-stimulated gene 12c protein) (ISG12(c)) (ISG12C)
Protein function Plays a role in the apoptotic process and has a pro-apoptotic activity.
PDB 2LOQ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06140 Ifi-6-16 11 → 96 Interferon-induced 6-16 family Family
Sequence
Sequence length 104
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Show/Hide Unknown Diseases (7)
Phenotype Name Clinical Significance Source Reference Evidence Score
Adrenocortical carcinoma, hereditary Likely risk allele ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Familial cancer of breast Likely risk allele ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Lung cancer Likely risk allele ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma Likely risk allele ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Leukemia Myeloid Acute Myeloid leukemia Pubtator 36102723 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only

No strongly related genes found yet for IFI27L1.

No additional diseases found yet through genes similar to IFI27L1.