IER5 (immediate early response 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51278 |
| Gene name | Immediate early response 5 |
| Gene symbol | IER5 |
| Synonyms (NCBI Gene) |
SBBI48
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| Chromosome | 1 |
| Chromosome location | 1q25.3 |
| Summary | This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene |
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miRNA
miRNA information provided by mirtarbase database.
315
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q5VY09 | |||||||||||||||
| Protein name | Immediate early response gene 5 protein | |||||||||||||||
| Protein function | Plays a role as a transcription factor (PubMed:22132193, PubMed:25355627). Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner (PubMed:25355627, PubMed:25816751). Medi | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in acute myeloid leukemia (AML) cells. {ECO:0000269|PubMed:22132193}. | |||||||||||||||
| Sequence |
MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGP |
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| Sequence length | 327 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Related Genes
Genes most often co-reported with IER5 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to IER5 (see Related Genes above), that are NOT already directly curated for IER5 itself -- a lead worth checking, not a confirmed association.
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