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Gene Gene information from NCBI Gene database.
Entrez ID 51278
Gene name Immediate early response 5
Gene symbol IER5
Synonyms (NCBI Gene)
SBBI48
Chromosome 1
Chromosome location 1q25.3
Summary This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene
miRNA miRNA information provided by mirtarbase database.
315 Show/Hide all (315)
miRTarBase ID miRNA Experiments Reference
MIRT016089 hsa-miR-744-5p Sequencing 20371350
MIRT028187 hsa-miR-33a-5p Sequencing 20371350
MIRT029804 hsa-miR-26b-5p Microarray 19088304
MIRT054217 hsa-miR-147b Luciferase reporter assayMicroarrayqRT-PCRWestern blot 23028679
MIRT657234 hsa-miR-532-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14 Show/Hide all (14)
GO ID Ontology Definition Evidence Reference
GO:0000159 Component Protein phosphatase type 2A complex IDA 25816751, 26496226
GO:0005515 Function Protein binding IPI 25816751, 26496226, 26754925
GO:0005634 Component Nucleus IDA 25816751
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607177 5393 ENSG00000162783
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5VY09
Protein name Immediate early response gene 5 protein
Protein function Plays a role as a transcription factor (PubMed:22132193, PubMed:25355627). Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner (PubMed:25355627, PubMed:25816751). Medi
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05760 IER 1 → 229 Immediate early response protein (IER) Family
PF05760 IER 226 → 327 Immediate early response protein (IER) Family
Tissue specificity TISSUE SPECIFICITY: Expressed in acute myeloid leukemia (AML) cells. {ECO:0000269|PubMed:22132193}.
Sequence
Sequence length 327
Interactions View interactions