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Gene Gene information from NCBI Gene database.
Entrez ID 3224
Gene name Homeobox C8
Gene symbol HOXC8
Synonyms (NCBI Gene)
HOX3HOX3A
Chromosome 12
Chromosome location 12q13.13
Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene cluster
miRNA miRNA information provided by mirtarbase database.
533 Show/Hide all (533)
miRTarBase ID miRNA Experiments Reference
MIRT002942 hsa-miR-196a-5p Western blot 19418581
MIRT002942 hsa-miR-196a-5p Review 20029422
MIRT004638 hsa-miR-196b-5p Review 20029422
MIRT002942 hsa-miR-196a-5p ImmunohistochemistryLuciferase reporter assayqRT-PCR 20736365
MIRT002942 hsa-miR-196a-5p ImmunohistochemistryLuciferase reporter assayqRT-PCR 20736365
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
BPTF Unknown 16728976
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20 Show/Hide all (20)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000785 Component Chromatin ISA
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
142970 5129 ENSG00000037965
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P31273
Protein name Homeobox protein Hox-C8 (Homeobox protein Hox-3A)
Protein function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00046 Homeodomain 150 → 206 Homeodomain Domain
Sequence
MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF
HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT
NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI
EVSHALGLTERQVKIWFQNRRMKWKK
ENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN
KD
Sequence length 242
Interactions View interactions