HOXC11 (homeobox C11)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 3227
• Gene name: Homeobox C11
• Gene symbol: HOXC11
• Synonyms (NCBI Gene): HOX3H
• Chromosome: 12
• Chromosome location: 12q13.13
• Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene cluster

miRNA Show/Hide all (191)

miRTarBase ID	miRNA	Experiments	Reference
MIRT048337	hsa-miR-106a-5p	CLASH	23622248
MIRT042340	hsa-miR-484	CLASH	23622248
MIRT037653	hsa-miR-744-5p	CLASH	23622248
MIRT036198	hsa-miR-320b	CLASH	23622248
MIRT513866	hsa-miR-3150a-5p	PAR-CLIP	23446348
MIRT513865	hsa-miR-3150b-5p	PAR-CLIP	23446348
MIRT513864	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT513863	hsa-miR-4643	PAR-CLIP	23446348
MIRT513862	hsa-miR-1273c	PAR-CLIP	23446348
MIRT513861	hsa-miR-3683	PAR-CLIP	23446348
MIRT513860	hsa-miR-466	PAR-CLIP	23446348
MIRT513866	hsa-miR-3150a-5p	PAR-CLIP	23446348
MIRT513865	hsa-miR-3150b-5p	PAR-CLIP	23446348
MIRT513864	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT513863	hsa-miR-4643	PAR-CLIP	23446348
MIRT513862	hsa-miR-1273c	PAR-CLIP	23446348
MIRT513861	hsa-miR-3683	PAR-CLIP	23446348
MIRT513860	hsa-miR-466	PAR-CLIP	23446348
MIRT1053518	hsa-let-7a	CLIP-seq
MIRT1053519	hsa-let-7b	CLIP-seq
MIRT1053520	hsa-let-7c	CLIP-seq
MIRT1053521	hsa-let-7d	CLIP-seq
MIRT1053522	hsa-let-7e	CLIP-seq
MIRT1053523	hsa-let-7f	CLIP-seq
MIRT1053524	hsa-let-7g	CLIP-seq
MIRT1053525	hsa-let-7i	CLIP-seq
MIRT1053526	hsa-miR-1197	CLIP-seq
MIRT1053527	hsa-miR-1228	CLIP-seq
MIRT1053528	hsa-miR-1470	CLIP-seq
MIRT1053529	hsa-miR-181a	CLIP-seq
MIRT1053530	hsa-miR-181b	CLIP-seq
MIRT1053531	hsa-miR-181c	CLIP-seq
MIRT1053532	hsa-miR-181d	CLIP-seq
MIRT1053533	hsa-miR-1908	CLIP-seq
MIRT1053534	hsa-miR-216a	CLIP-seq
MIRT1053535	hsa-miR-22	CLIP-seq
MIRT1053536	hsa-miR-2276	CLIP-seq
MIRT1053537	hsa-miR-23a	CLIP-seq
MIRT1053538	hsa-miR-23b	CLIP-seq
MIRT1053539	hsa-miR-23c	CLIP-seq
MIRT1053540	hsa-miR-2467-3p	CLIP-seq
MIRT1053541	hsa-miR-27a	CLIP-seq
MIRT1053542	hsa-miR-27b	CLIP-seq
MIRT1053543	hsa-miR-3127-5p	CLIP-seq
MIRT1053544	hsa-miR-3150a-3p	CLIP-seq
MIRT1053545	hsa-miR-3151	CLIP-seq
MIRT1053546	hsa-miR-3153	CLIP-seq
MIRT1053547	hsa-miR-3175	CLIP-seq
MIRT1053548	hsa-miR-3180	CLIP-seq
MIRT1053549	hsa-miR-3180-3p	CLIP-seq
MIRT1053550	hsa-miR-3196	CLIP-seq
MIRT1053551	hsa-miR-329	CLIP-seq
MIRT1053552	hsa-miR-362-3p	CLIP-seq
MIRT1053553	hsa-miR-3941	CLIP-seq
MIRT1053554	hsa-miR-3978	CLIP-seq
MIRT1053555	hsa-miR-4262	CLIP-seq
MIRT1053556	hsa-miR-4446-5p	CLIP-seq
MIRT1053557	hsa-miR-4458	CLIP-seq
MIRT1053558	hsa-miR-4462	CLIP-seq
MIRT1053559	hsa-miR-4488	CLIP-seq
MIRT1053560	hsa-miR-4500	CLIP-seq
MIRT1053561	hsa-miR-4645-5p	CLIP-seq
MIRT1053562	hsa-miR-4667-3p	CLIP-seq
MIRT1053563	hsa-miR-4668-3p	CLIP-seq
MIRT1053564	hsa-miR-4668-5p	CLIP-seq
MIRT1053565	hsa-miR-4673	CLIP-seq
MIRT1053566	hsa-miR-4697-5p	CLIP-seq
MIRT1053567	hsa-miR-4699-3p	CLIP-seq
MIRT1053568	hsa-miR-4708-5p	CLIP-seq
MIRT1053569	hsa-miR-4716-3p	CLIP-seq
MIRT1053570	hsa-miR-4723-5p	CLIP-seq
MIRT1053571	hsa-miR-4750	CLIP-seq
MIRT1053572	hsa-miR-4755-5p	CLIP-seq
MIRT1053573	hsa-miR-4761-5p	CLIP-seq
MIRT1053574	hsa-miR-4798-3p	CLIP-seq
MIRT1053575	hsa-miR-491-5p	CLIP-seq
MIRT1053576	hsa-miR-493	CLIP-seq
MIRT1053577	hsa-miR-507	CLIP-seq
MIRT1053578	hsa-miR-520d-5p	CLIP-seq
MIRT1053579	hsa-miR-524-5p	CLIP-seq
MIRT1053580	hsa-miR-548c-3p	CLIP-seq
MIRT1053581	hsa-miR-557	CLIP-seq
MIRT1053582	hsa-miR-603	CLIP-seq
MIRT1053583	hsa-miR-637	CLIP-seq
MIRT1053584	hsa-miR-642a	CLIP-seq
MIRT1053585	hsa-miR-645	CLIP-seq
MIRT1053586	hsa-miR-663	CLIP-seq
MIRT1053587	hsa-miR-744	CLIP-seq
MIRT1053588	hsa-miR-939	CLIP-seq
MIRT1053589	hsa-miR-98	CLIP-seq
MIRT2012161	hsa-miR-1973	CLIP-seq
MIRT1053537	hsa-miR-23a	CLIP-seq
MIRT1053538	hsa-miR-23b	CLIP-seq
MIRT1053539	hsa-miR-23c	CLIP-seq
MIRT2012162	hsa-miR-3650	CLIP-seq
MIRT2012163	hsa-miR-4711-5p	CLIP-seq
MIRT2012164	hsa-miR-517b	CLIP-seq
MIRT1053526	hsa-miR-1197	CLIP-seq
MIRT1053527	hsa-miR-1228	CLIP-seq
MIRT1053529	hsa-miR-181a	CLIP-seq
MIRT1053530	hsa-miR-181b	CLIP-seq
MIRT1053531	hsa-miR-181c	CLIP-seq
MIRT1053532	hsa-miR-181d	CLIP-seq
MIRT2012161	hsa-miR-1973	CLIP-seq
MIRT1053534	hsa-miR-216a	CLIP-seq
MIRT1053535	hsa-miR-22	CLIP-seq
MIRT1053537	hsa-miR-23a	CLIP-seq
MIRT1053538	hsa-miR-23b	CLIP-seq
MIRT1053539	hsa-miR-23c	CLIP-seq
MIRT2244502	hsa-miR-24	CLIP-seq
MIRT1053540	hsa-miR-2467-3p	CLIP-seq
MIRT1053541	hsa-miR-27a	CLIP-seq
MIRT1053542	hsa-miR-27b	CLIP-seq
MIRT2244503	hsa-miR-3119	CLIP-seq
MIRT1053543	hsa-miR-3127-5p	CLIP-seq
MIRT2244504	hsa-miR-3148	CLIP-seq
MIRT1053544	hsa-miR-3150a-3p	CLIP-seq
MIRT1053545	hsa-miR-3151	CLIP-seq
MIRT1053547	hsa-miR-3175	CLIP-seq
MIRT2244505	hsa-miR-3190	CLIP-seq
MIRT2244506	hsa-miR-3192	CLIP-seq
MIRT2244507	hsa-miR-3202	CLIP-seq
MIRT2244508	hsa-miR-326	CLIP-seq
MIRT1053551	hsa-miR-329	CLIP-seq
MIRT2244509	hsa-miR-330-5p	CLIP-seq
MIRT2244510	hsa-miR-3591-3p	CLIP-seq
MIRT2244511	hsa-miR-3616-5p	CLIP-seq
MIRT1053552	hsa-miR-362-3p	CLIP-seq
MIRT2244512	hsa-miR-3647-5p	CLIP-seq
MIRT2244513	hsa-miR-3679-3p	CLIP-seq
MIRT2244514	hsa-miR-3689d	CLIP-seq
MIRT2244515	hsa-miR-375	CLIP-seq
MIRT2244516	hsa-miR-3937	CLIP-seq
MIRT1053553	hsa-miR-3941	CLIP-seq
MIRT1053554	hsa-miR-3978	CLIP-seq
MIRT2244517	hsa-miR-4261	CLIP-seq
MIRT1053555	hsa-miR-4262	CLIP-seq
MIRT2244518	hsa-miR-4314	CLIP-seq
MIRT2244519	hsa-miR-4445	CLIP-seq
MIRT1053556	hsa-miR-4446-5p	CLIP-seq
MIRT2244520	hsa-miR-4459	CLIP-seq
MIRT1053558	hsa-miR-4462	CLIP-seq
MIRT2244521	hsa-miR-4476	CLIP-seq
MIRT2244522	hsa-miR-4491	CLIP-seq
MIRT1053561	hsa-miR-4645-5p	CLIP-seq
MIRT2244523	hsa-miR-4646-5p	CLIP-seq
MIRT2244524	hsa-miR-4657	CLIP-seq
MIRT1053563	hsa-miR-4668-3p	CLIP-seq
MIRT1053565	hsa-miR-4673	CLIP-seq
MIRT1053568	hsa-miR-4708-5p	CLIP-seq
MIRT2244525	hsa-miR-4717-3p	CLIP-seq
MIRT1053570	hsa-miR-4723-5p	CLIP-seq
MIRT2244526	hsa-miR-4733-3p	CLIP-seq
MIRT2244527	hsa-miR-4747-5p	CLIP-seq
MIRT1053572	hsa-miR-4755-5p	CLIP-seq
MIRT2244528	hsa-miR-4775	CLIP-seq
MIRT2244529	hsa-miR-4795-5p	CLIP-seq
MIRT2244530	hsa-miR-486-3p	CLIP-seq
MIRT1053575	hsa-miR-491-5p	CLIP-seq
MIRT1053576	hsa-miR-493	CLIP-seq
MIRT2244531	hsa-miR-501-3p	CLIP-seq
MIRT2244532	hsa-miR-502-3p	CLIP-seq
MIRT1053577	hsa-miR-507	CLIP-seq
MIRT2012164	hsa-miR-517b	CLIP-seq
MIRT2244533	hsa-miR-521	CLIP-seq
MIRT1053580	hsa-miR-548c-3p	CLIP-seq
MIRT1053581	hsa-miR-557	CLIP-seq
MIRT2244534	hsa-miR-573	CLIP-seq
MIRT2244535	hsa-miR-576-3p	CLIP-seq
MIRT2244536	hsa-miR-590-3p	CLIP-seq
MIRT1053582	hsa-miR-603	CLIP-seq
MIRT1053584	hsa-miR-642a	CLIP-seq
MIRT2244537	hsa-miR-665	CLIP-seq
MIRT1053588	hsa-miR-939	CLIP-seq
MIRT1053537	hsa-miR-23a	CLIP-seq
MIRT1053538	hsa-miR-23b	CLIP-seq
MIRT1053539	hsa-miR-23c	CLIP-seq
MIRT1053541	hsa-miR-27a	CLIP-seq
MIRT1053542	hsa-miR-27b	CLIP-seq
MIRT1053551	hsa-miR-329	CLIP-seq
MIRT1053552	hsa-miR-362-3p	CLIP-seq
MIRT1053553	hsa-miR-3941	CLIP-seq
MIRT1053574	hsa-miR-4798-3p	CLIP-seq
MIRT2244533	hsa-miR-521	CLIP-seq
MIRT1053582	hsa-miR-603	CLIP-seq
MIRT1053551	hsa-miR-329	CLIP-seq
MIRT1053552	hsa-miR-362-3p	CLIP-seq
MIRT1053553	hsa-miR-3941	CLIP-seq
MIRT1053574	hsa-miR-4798-3p	CLIP-seq
MIRT2244533	hsa-miR-521	CLIP-seq
MIRT1053582	hsa-miR-603	CLIP-seq

Gene ontology (GO) Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	9582375
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	9582375
GO:0001501	Process	Skeletal system development	IEA
GO:0001656	Process	Metanephros development	IEA
GO:0001759	Process	Organ induction	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	23275563, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007492	Process	Endoderm development	TAS	9582375
GO:0009952	Process	Anterior/posterior pattern specification	IEA
GO:0009954	Process	Proximal/distal pattern formation	IEA
GO:0042733	Process	Embryonic digit morphogenesis	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	9582375
GO:0060272	Process	Embryonic skeletal joint morphogenesis	IBA
GO:0060272	Process	Embryonic skeletal joint morphogenesis	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 605559
• HGNC: 5123
• e!Ensembl: ENSG00000123388

Protein

• UniProt ID: O43248
• Protein name: Homeobox protein Hox-C11 (Homeobox protein Hox-3H)
• Protein function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00046	Homeodomain	233 → 289	Homeodomain	Domain
  PF12045	DUF3528	42 → 178	Protein of unknown function (DUF3528)	Family

• Sequence:

  MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFSTVSSFLPQAPSRQIS
  YPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGS
  YGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGE
  PEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYS
  KFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSG
  NPLL

• Sequence length: 304

Related Genes

No strongly related genes found yet for HOXC11.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to HOXC11.