HOXC10 (homeobox C10)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 3226
• Gene name: Homeobox C10
• Gene symbol: HOXC10
• Synonyms (NCBI Gene): HOX3I
• Chromosome: 12
• Chromosome location: 12q13.13
• Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene cluster

miRNA Show/Hide all (97)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024207	hsa-miR-221-3p	qRT-PCR	20516212
MIRT027074	hsa-miR-103a-3p	Sequencing	20371350
MIRT1053488	hsa-miR-103a	CLIP-seq
MIRT1053489	hsa-miR-107	CLIP-seq
MIRT1053490	hsa-miR-1273f	CLIP-seq
MIRT1053491	hsa-miR-1275	CLIP-seq
MIRT1053492	hsa-miR-129-5p	CLIP-seq
MIRT1053493	hsa-miR-143	CLIP-seq
MIRT1053494	hsa-miR-28-3p	CLIP-seq
MIRT1053495	hsa-miR-299-3p	CLIP-seq
MIRT1053496	hsa-miR-3151	CLIP-seq
MIRT1053497	hsa-miR-3152-5p	CLIP-seq
MIRT1053498	hsa-miR-3173-3p	CLIP-seq
MIRT1053499	hsa-miR-342-5p	CLIP-seq
MIRT1053500	hsa-miR-4428	CLIP-seq
MIRT1053501	hsa-miR-4447	CLIP-seq
MIRT1053502	hsa-miR-4472	CLIP-seq
MIRT1053503	hsa-miR-4474-5p	CLIP-seq
MIRT1053504	hsa-miR-450b-5p	CLIP-seq
MIRT1053505	hsa-miR-4521	CLIP-seq
MIRT1053506	hsa-miR-4525	CLIP-seq
MIRT1053507	hsa-miR-4664-5p	CLIP-seq
MIRT1053508	hsa-miR-4665-5p	CLIP-seq
MIRT1053509	hsa-miR-4708-5p	CLIP-seq
MIRT1053510	hsa-miR-4723-5p	CLIP-seq
MIRT1053511	hsa-miR-4764-5p	CLIP-seq
MIRT1053512	hsa-miR-4770	CLIP-seq
MIRT1053513	hsa-miR-4774-3p	CLIP-seq
MIRT1053514	hsa-miR-491-5p	CLIP-seq
MIRT1053515	hsa-miR-507	CLIP-seq
MIRT1053516	hsa-miR-557	CLIP-seq
MIRT1053517	hsa-miR-625	CLIP-seq
MIRT2012160	hsa-miR-3148	CLIP-seq
MIRT1053488	hsa-miR-103a	CLIP-seq
MIRT1053489	hsa-miR-107	CLIP-seq
MIRT2244476	hsa-miR-1252	CLIP-seq
MIRT1053491	hsa-miR-1275	CLIP-seq
MIRT2244477	hsa-miR-1324	CLIP-seq
MIRT2244478	hsa-miR-185	CLIP-seq
MIRT1053498	hsa-miR-3173-3p	CLIP-seq
MIRT2244479	hsa-miR-3190	CLIP-seq
MIRT2244480	hsa-miR-3192	CLIP-seq
MIRT2244481	hsa-miR-329	CLIP-seq
MIRT2244482	hsa-miR-338-5p	CLIP-seq
MIRT2244483	hsa-miR-3616-3p	CLIP-seq
MIRT2244484	hsa-miR-3617	CLIP-seq
MIRT2244485	hsa-miR-362-3p	CLIP-seq
MIRT2244486	hsa-miR-3689a-3p	CLIP-seq
MIRT2244487	hsa-miR-3689c	CLIP-seq
MIRT2244488	hsa-miR-4260	CLIP-seq
MIRT2244489	hsa-miR-4306	CLIP-seq
MIRT1053500	hsa-miR-4428	CLIP-seq
MIRT2244490	hsa-miR-4436a	CLIP-seq
MIRT1053503	hsa-miR-4474-5p	CLIP-seq
MIRT2244491	hsa-miR-4476	CLIP-seq
MIRT1053505	hsa-miR-4521	CLIP-seq
MIRT2244492	hsa-miR-4533	CLIP-seq
MIRT2244493	hsa-miR-4644	CLIP-seq
MIRT1053508	hsa-miR-4665-5p	CLIP-seq
MIRT2244494	hsa-miR-4700-3p	CLIP-seq
MIRT2244495	hsa-miR-4721	CLIP-seq
MIRT2244496	hsa-miR-4728-5p	CLIP-seq
MIRT2244497	hsa-miR-4802-3p	CLIP-seq
MIRT2244498	hsa-miR-498	CLIP-seq
MIRT2244499	hsa-miR-548u	CLIP-seq
MIRT2244500	hsa-miR-641	CLIP-seq
MIRT2244501	hsa-miR-671-5p	CLIP-seq
MIRT2451343	hsa-miR-4775	CLIP-seq
MIRT2451344	hsa-miR-590-3p	CLIP-seq
MIRT1053490	hsa-miR-1273f	CLIP-seq
MIRT1053491	hsa-miR-1275	CLIP-seq
MIRT1053493	hsa-miR-143	CLIP-seq
MIRT1053494	hsa-miR-28-3p	CLIP-seq
MIRT2547395	hsa-miR-4251	CLIP-seq
MIRT2547396	hsa-miR-4303	CLIP-seq
MIRT2547397	hsa-miR-4329	CLIP-seq
MIRT1053506	hsa-miR-4525	CLIP-seq
MIRT1053508	hsa-miR-4665-5p	CLIP-seq
MIRT1053509	hsa-miR-4708-5p	CLIP-seq
MIRT1053510	hsa-miR-4723-5p	CLIP-seq
MIRT2547398	hsa-miR-4762-3p	CLIP-seq
MIRT1053512	hsa-miR-4770	CLIP-seq
MIRT1053517	hsa-miR-625	CLIP-seq
MIRT1053490	hsa-miR-1273f	CLIP-seq
MIRT1053491	hsa-miR-1275	CLIP-seq
MIRT1053493	hsa-miR-143	CLIP-seq
MIRT1053494	hsa-miR-28-3p	CLIP-seq
MIRT2547395	hsa-miR-4251	CLIP-seq
MIRT2547396	hsa-miR-4303	CLIP-seq
MIRT2547397	hsa-miR-4329	CLIP-seq
MIRT1053506	hsa-miR-4525	CLIP-seq
MIRT1053508	hsa-miR-4665-5p	CLIP-seq
MIRT1053509	hsa-miR-4708-5p	CLIP-seq
MIRT1053510	hsa-miR-4723-5p	CLIP-seq
MIRT2547398	hsa-miR-4762-3p	CLIP-seq
MIRT1053512	hsa-miR-4770	CLIP-seq
MIRT1053517	hsa-miR-625	CLIP-seq

Gene ontology (GO) Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	10835276
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	10835276
GO:0001501	Process	Skeletal system development	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008284	Process	Positive regulation of cell population proliferation	TAS	10835276
GO:0009952	Process	Anterior/posterior pattern specification	IEA
GO:0009954	Process	Proximal/distal pattern formation	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0021520	Process	Spinal cord motor neuron cell fate specification	IEA
GO:0030326	Process	Embryonic limb morphogenesis	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	10835276
GO:0050905	Process	Neuromuscular process	IEA
GO:0120163	Process	Negative regulation of cold-induced thermogenesis	IMP	28186086
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

Other IDs

• MIM: 605560
• HGNC: 5122
• e!Ensembl: ENSG00000180818

Protein

• UniProt ID: Q9NYD6
• Protein name: Homeobox protein Hox-C10 (Homeobox protein Hox-3I)
• Protein function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00046	Homeodomain	269 → 325	Homeodomain	Domain

• Sequence:

  MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGS
  SPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRA
  KSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASL
  NPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKERAKAADS
  SPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLE
  ISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT

• Sequence length: 342

Related Genes

No strongly related genes found yet for HOXC10.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to HOXC10.