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Gene Gene information from NCBI Gene database.
Entrez ID 25994
Gene name HIG1 hypoxia inducible domain family member 1A
Gene symbol HIGD1A
Synonyms (NCBI Gene)
HIG1RCF1a
Chromosome 3
Chromosome location 3p22.1
miRNA miRNA information provided by mirtarbase database.
709 Show/Hide all (709)
miRTarBase ID miRNA Experiments Reference
MIRT023908 hsa-miR-1-3p Microarray 18668037
MIRT031840 hsa-miR-16-5p Proteomics 18668040
MIRT036058 hsa-miR-1301-3p CLASH 23622248
MIRT547973 hsa-miR-6838-5p PAR-CLIP 20371350
MIRT547972 hsa-miR-15b-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17 Show/Hide all (17)
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IBA
GO:0005739 Component Mitochondrion IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
618623 29527 ENSG00000181061
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y241
Protein name HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) (RCF1 homolog A) (RCF1a)
Protein function Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes. {E
PDB 2LOM
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04588 HIG_1_N 26 → 78 Hypoxia induced protein conserved region Family
Sequence
MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL
IHMRVAAQGFVVGAMTVG
MGYSMYREFWAKPKP
Sequence length 93
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Regulation of gene expression by Hypoxia-inducible Factor