HECTD3 (HECT domain E3 ubiquitin protein ligase 3)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 79654
• Gene name: HECT domain E3 ubiquitin protein ligase 3
• Gene symbol: HECTD3
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1p34.1
• Summary: The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycl

miRNA Show/Hide all (270)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023327	hsa-miR-122-5p	Microarray	17612493
MIRT025780	hsa-miR-7-5p	Microarray	19073608
MIRT029557	hsa-miR-26b-5p	Microarray	19088304
MIRT041762	hsa-miR-484	CLASH	23622248
MIRT039878	hsa-miR-615-3p	CLASH	23622248
MIRT674629	hsa-miR-5693	HITS-CLIP	23824327
MIRT138483	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT674628	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT674627	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT674626	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT674625	hsa-miR-4284	HITS-CLIP	23824327
MIRT674624	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT667981	hsa-miR-7977	HITS-CLIP	23824327
MIRT674623	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT667994	hsa-miR-3714	HITS-CLIP	23824327
MIRT667993	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT667992	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT667991	hsa-miR-1324	HITS-CLIP	23824327
MIRT667990	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT667989	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT667988	hsa-miR-3166	HITS-CLIP	23824327
MIRT667987	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT667986	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT667985	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT667984	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT667983	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT667982	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT667981	hsa-miR-7977	HITS-CLIP	23824327
MIRT667980	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT667979	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT667978	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT667977	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT667976	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT667975	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT667974	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT667973	hsa-miR-3689c	HITS-CLIP	23824327
MIRT667972	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT667971	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT667970	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT667969	hsa-miR-3122	HITS-CLIP	23824327
MIRT667968	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT667967	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT667966	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT455933	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT455932	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT455931	hsa-miR-219a-2-3p	PAR-CLIP	23592263
MIRT455930	hsa-miR-6087	PAR-CLIP	23592263
MIRT455929	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT455928	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT455927	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT455926	hsa-miR-4459	PAR-CLIP	23592263
MIRT727508	hsa-miR-26a-5p	HITS-CLIP	22473208
MIRT029557	hsa-miR-26b-5p	HITS-CLIP	22473208
MIRT674629	hsa-miR-5693	HITS-CLIP	23824327
MIRT138483	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT674628	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT674627	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT674626	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT674625	hsa-miR-4284	HITS-CLIP	23824327
MIRT674624	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT667981	hsa-miR-7977	HITS-CLIP	23824327
MIRT674623	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT667994	hsa-miR-3714	HITS-CLIP	23824327
MIRT667993	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT667992	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT667991	hsa-miR-1324	HITS-CLIP	23824327
MIRT667990	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT667989	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT667988	hsa-miR-3166	HITS-CLIP	23824327
MIRT667987	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT667986	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT667985	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT667984	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT667983	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT667982	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT667981	hsa-miR-7977	HITS-CLIP	23824327
MIRT667980	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT667979	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT667978	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT667977	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT667976	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT667975	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT667974	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT667973	hsa-miR-3689c	HITS-CLIP	23824327
MIRT667972	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT667971	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT667970	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT667969	hsa-miR-3122	HITS-CLIP	23824327
MIRT667968	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT667967	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT667966	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT455933	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT455932	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT455931	hsa-miR-219a-2-3p	PAR-CLIP	23592263
MIRT455930	hsa-miR-6087	PAR-CLIP	23592263
MIRT455929	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT455928	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT455927	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT455926	hsa-miR-4459	PAR-CLIP	23592263
MIRT1043548	hsa-miR-1180	CLIP-seq
MIRT1043549	hsa-miR-1207-5p	CLIP-seq
MIRT1043550	hsa-miR-122	CLIP-seq
MIRT1043551	hsa-miR-1237	CLIP-seq
MIRT1043552	hsa-miR-1248	CLIP-seq
MIRT1043553	hsa-miR-125a-5p	CLIP-seq
MIRT1043554	hsa-miR-125b	CLIP-seq
MIRT1043555	hsa-miR-1275	CLIP-seq
MIRT1043556	hsa-miR-1291	CLIP-seq
MIRT1043557	hsa-miR-1297	CLIP-seq
MIRT1043558	hsa-miR-1321	CLIP-seq
MIRT1043559	hsa-miR-1909	CLIP-seq
MIRT1043560	hsa-miR-1972	CLIP-seq
MIRT1043561	hsa-miR-19a	CLIP-seq
MIRT1043562	hsa-miR-19b	CLIP-seq
MIRT1043563	hsa-miR-2110	CLIP-seq
MIRT1043564	hsa-miR-2115	CLIP-seq
MIRT1043565	hsa-miR-218	CLIP-seq
MIRT1043566	hsa-miR-26a	CLIP-seq
MIRT1043567	hsa-miR-26b	CLIP-seq
MIRT1043568	hsa-miR-3126-5p	CLIP-seq
MIRT1043569	hsa-miR-3127-3p	CLIP-seq
MIRT1043570	hsa-miR-3135b	CLIP-seq
MIRT1043571	hsa-miR-3144-5p	CLIP-seq
MIRT1043572	hsa-miR-3150a-3p	CLIP-seq
MIRT1043573	hsa-miR-3155	CLIP-seq
MIRT1043574	hsa-miR-3155b	CLIP-seq
MIRT1043575	hsa-miR-3160-3p	CLIP-seq
MIRT1043576	hsa-miR-3190	CLIP-seq
MIRT1043577	hsa-miR-3191	CLIP-seq
MIRT1043578	hsa-miR-3612	CLIP-seq
MIRT1043579	hsa-miR-3647-3p	CLIP-seq
MIRT1043580	hsa-miR-3649	CLIP-seq
MIRT1043581	hsa-miR-3652	CLIP-seq
MIRT1043582	hsa-miR-378g	CLIP-seq
MIRT1043583	hsa-miR-3928	CLIP-seq
MIRT1043584	hsa-miR-3940-5p	CLIP-seq
MIRT1043585	hsa-miR-4270	CLIP-seq
MIRT1043586	hsa-miR-4272	CLIP-seq
MIRT1043587	hsa-miR-4313	CLIP-seq
MIRT1043588	hsa-miR-4319	CLIP-seq
MIRT1043589	hsa-miR-432	CLIP-seq
MIRT1043590	hsa-miR-4419a	CLIP-seq
MIRT1043591	hsa-miR-4430	CLIP-seq
MIRT1043592	hsa-miR-4436b-3p	CLIP-seq
MIRT1043593	hsa-miR-4441	CLIP-seq
MIRT1043594	hsa-miR-4443	CLIP-seq
MIRT1043595	hsa-miR-4465	CLIP-seq
MIRT1043596	hsa-miR-4484	CLIP-seq
MIRT1043597	hsa-miR-4507	CLIP-seq
MIRT1043598	hsa-miR-4510	CLIP-seq
MIRT1043599	hsa-miR-4650-5p	CLIP-seq
MIRT1043600	hsa-miR-4652-5p	CLIP-seq
MIRT1043601	hsa-miR-4664-3p	CLIP-seq
MIRT1043602	hsa-miR-4665-5p	CLIP-seq
MIRT1043603	hsa-miR-4694-3p	CLIP-seq
MIRT1043604	hsa-miR-4699-5p	CLIP-seq
MIRT1043605	hsa-miR-4729	CLIP-seq
MIRT1043606	hsa-miR-4731-5p	CLIP-seq
MIRT1043607	hsa-miR-4739	CLIP-seq
MIRT1043608	hsa-miR-4752	CLIP-seq
MIRT1043609	hsa-miR-4756-5p	CLIP-seq
MIRT1043610	hsa-miR-4763-3p	CLIP-seq
MIRT1043611	hsa-miR-4802-5p	CLIP-seq
MIRT1043612	hsa-miR-488	CLIP-seq
MIRT1043613	hsa-miR-516a-3p	CLIP-seq
MIRT1043614	hsa-miR-544b	CLIP-seq
MIRT1043615	hsa-miR-548g	CLIP-seq
MIRT1043616	hsa-miR-562	CLIP-seq
MIRT1043617	hsa-miR-597	CLIP-seq
MIRT1043618	hsa-miR-635	CLIP-seq
MIRT1043619	hsa-miR-642a	CLIP-seq
MIRT1043620	hsa-miR-650	CLIP-seq
MIRT1043621	hsa-miR-7	CLIP-seq
MIRT1043622	hsa-miR-875-5p	CLIP-seq
MIRT1043623	hsa-miR-885-3p	CLIP-seq
MIRT1043548	hsa-miR-1180	CLIP-seq
MIRT2009409	hsa-miR-147	CLIP-seq
MIRT1043565	hsa-miR-218	CLIP-seq
MIRT1043576	hsa-miR-3190	CLIP-seq
MIRT2009410	hsa-miR-3529	CLIP-seq
MIRT2009411	hsa-miR-3672	CLIP-seq
MIRT1043582	hsa-miR-378g	CLIP-seq
MIRT2009412	hsa-miR-379	CLIP-seq
MIRT1043584	hsa-miR-3940-5p	CLIP-seq
MIRT1043586	hsa-miR-4272	CLIP-seq
MIRT2009413	hsa-miR-4451	CLIP-seq
MIRT2009414	hsa-miR-4463	CLIP-seq
MIRT1043597	hsa-miR-4507	CLIP-seq
MIRT2009415	hsa-miR-4650-3p	CLIP-seq
MIRT1043601	hsa-miR-4664-3p	CLIP-seq
MIRT1043605	hsa-miR-4729	CLIP-seq
MIRT1043606	hsa-miR-4731-5p	CLIP-seq
MIRT1043608	hsa-miR-4752	CLIP-seq
MIRT2009416	hsa-miR-599	CLIP-seq
MIRT1043621	hsa-miR-7	CLIP-seq
MIRT1043548	hsa-miR-1180	CLIP-seq
MIRT1043549	hsa-miR-1207-5p	CLIP-seq
MIRT2241787	hsa-miR-125a-3p	CLIP-seq
MIRT1043557	hsa-miR-1297	CLIP-seq
MIRT1043558	hsa-miR-1321	CLIP-seq
MIRT2241788	hsa-miR-153	CLIP-seq
MIRT1043559	hsa-miR-1909	CLIP-seq
MIRT1043560	hsa-miR-1972	CLIP-seq
MIRT1043563	hsa-miR-2110	CLIP-seq
MIRT1043565	hsa-miR-218	CLIP-seq
MIRT1043566	hsa-miR-26a	CLIP-seq
MIRT1043567	hsa-miR-26b	CLIP-seq
MIRT1043572	hsa-miR-3150a-3p	CLIP-seq
MIRT1043573	hsa-miR-3155	CLIP-seq
MIRT1043574	hsa-miR-3155b	CLIP-seq
MIRT1043576	hsa-miR-3190	CLIP-seq
MIRT2241789	hsa-miR-3665	CLIP-seq
MIRT1043582	hsa-miR-378g	CLIP-seq
MIRT2241790	hsa-miR-3914	CLIP-seq
MIRT1043583	hsa-miR-3928	CLIP-seq
MIRT1043586	hsa-miR-4272	CLIP-seq
MIRT1043590	hsa-miR-4419a	CLIP-seq
MIRT1043592	hsa-miR-4436b-3p	CLIP-seq
MIRT2241791	hsa-miR-4455	CLIP-seq
MIRT1043595	hsa-miR-4465	CLIP-seq
MIRT1043598	hsa-miR-4510	CLIP-seq
MIRT1043599	hsa-miR-4650-5p	CLIP-seq
MIRT1043601	hsa-miR-4664-3p	CLIP-seq
MIRT2241792	hsa-miR-4668-5p	CLIP-seq
MIRT1043604	hsa-miR-4699-5p	CLIP-seq
MIRT2241793	hsa-miR-4717-3p	CLIP-seq
MIRT1043605	hsa-miR-4729	CLIP-seq
MIRT1043606	hsa-miR-4731-5p	CLIP-seq
MIRT1043607	hsa-miR-4739	CLIP-seq
MIRT2241794	hsa-miR-4747-5p	CLIP-seq
MIRT1043608	hsa-miR-4752	CLIP-seq
MIRT1043609	hsa-miR-4756-5p	CLIP-seq
MIRT1043610	hsa-miR-4763-3p	CLIP-seq
MIRT1043611	hsa-miR-4802-5p	CLIP-seq
MIRT1043615	hsa-miR-548g	CLIP-seq
MIRT1043616	hsa-miR-562	CLIP-seq
MIRT1043621	hsa-miR-7	CLIP-seq
MIRT1043623	hsa-miR-885-3p	CLIP-seq
MIRT2009409	hsa-miR-147	CLIP-seq
MIRT1043572	hsa-miR-3150a-3p	CLIP-seq
MIRT2388928	hsa-miR-3175	CLIP-seq
MIRT2009410	hsa-miR-3529	CLIP-seq
MIRT2009411	hsa-miR-3672	CLIP-seq
MIRT2009412	hsa-miR-379	CLIP-seq
MIRT1043584	hsa-miR-3940-5p	CLIP-seq
MIRT2009413	hsa-miR-4451	CLIP-seq
MIRT2009414	hsa-miR-4463	CLIP-seq
MIRT1043597	hsa-miR-4507	CLIP-seq
MIRT2009415	hsa-miR-4650-3p	CLIP-seq
MIRT2388929	hsa-miR-4773	CLIP-seq
MIRT2009416	hsa-miR-599	CLIP-seq
MIRT2388930	hsa-miR-939	CLIP-seq
MIRT1043549	hsa-miR-1207-5p	CLIP-seq
MIRT1043553	hsa-miR-125a-5p	CLIP-seq
MIRT1043554	hsa-miR-125b	CLIP-seq
MIRT1043556	hsa-miR-1291	CLIP-seq
MIRT1043558	hsa-miR-1321	CLIP-seq
MIRT2241788	hsa-miR-153	CLIP-seq
MIRT1043559	hsa-miR-1909	CLIP-seq
MIRT1043568	hsa-miR-3126-5p	CLIP-seq
MIRT1043583	hsa-miR-3928	CLIP-seq
MIRT1043588	hsa-miR-4319	CLIP-seq
MIRT1043590	hsa-miR-4419a	CLIP-seq
MIRT2241791	hsa-miR-4455	CLIP-seq
MIRT1043598	hsa-miR-4510	CLIP-seq
MIRT1043607	hsa-miR-4739	CLIP-seq
MIRT1043609	hsa-miR-4756-5p	CLIP-seq
MIRT1043610	hsa-miR-4763-3p	CLIP-seq
MIRT1043614	hsa-miR-544b	CLIP-seq
MIRT1043615	hsa-miR-548g	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004842	Function	Ubiquitin-protein transferase activity	IBA
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	18194665
GO:0004842	Function	Ubiquitin-protein transferase activity	IEA
GO:0004842	Function	Ubiquitin-protein transferase activity	ISS
GO:0005515	Function	Protein binding	IPI	18194665, 32296183, 32814053
GO:0005737	Component	Cytoplasm	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0019905	Function	Syntaxin binding	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	18194665
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	ISS
GO:0061630	Function	Ubiquitin protein ligase activity	IEA

Other IDs

• MIM: 618638
• HGNC: 26117
• e!Ensembl: ENSG00000126107

Protein

• UniProt ID: Q5T447
• Protein name: E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3)
• Protein function: E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradat
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00632	HECT	562 → 852	HECT-domain (ubiquitin-transferase)	Domain
  PF03256	ANAPC10	232 → 393	Anaphase-promoting complex, subunit 10 (APC10)	Family

• Sequence:

  MAGPGPGAVLESPRQLLGRVRFLAEAARSLRAGRPLPAALAFVPREVLYKLYKDPAGPSR
  VLLPVWEAEGLGLRVGAAGPAPGTGSGPLRAARDSIELRRGACVRTTGEELCNGHGLWVK
  LTKEQLAEHLGDCGLQEGWLLVCRPAEGGARLVPIDTPNHLQRQQQLFGVDYRPVLRWEQ
  VVDLTYSHRLGSRPQPAEAYAEAVQRLLYVPPTWTYECDEDLIHFLYDHLGKEDENLGSV
  KQYVESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDT
  TDDNFMPKRVVVYGGEGDNLKKLSDVSIDETLIGDVCVLEDMTVHLPIIEIRIVECRDDG
  IDVRLRGVKIKSSRQRELGLNADLFQPTSLVRYPRLEGTDPEVLYRRAVLLQRFIKILDS
  VLHHLVPAWDHTLGTFSEIKQVKQFLLLSRQRPGLVAQCLRDSESSKPSFMPRLYINRRL
  AMEHRACPSRDPACKNAVFTQVYEGLKPSDKYEKPLDYRWPMRYDQWWECKFIAEGIIDQ
  GGGFRDSLADMSEELCPSSADTPVPLPFFVRTANQGNGTGEARDMYVPNPSCRDFAKYEW
  IGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSKDFPAVDSVLVKLLEVMEGMDKETF
  EFKFGKELTFTTVLSDQQVVELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQVAAMQA
  GLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDSRVQYFWEALNNF
  TNEDRSRFLRFVTGRSRLPARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEE
  KLRYAAYNCVAIDTDMSPWEE

• Sequence length: 861

Pathways

Reactome Pathway:

Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Cervical cancer	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian cancer	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (8)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Neoplasms	Breast neoplasm	Pubtator	29685151	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	28989055		★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	28989055		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28989055, 31637449		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	28636940, 28716524		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	28989055		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	28716524		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for HECTD3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to HECTD3.