GTPBP6 (GTP binding protein 6)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 8225
• Gene name: GTP binding protein 6
• Gene symbol: GTPBP6
• Synonyms (NCBI Gene): PGPL
• Chromosome: X|Y
• Chromosome location: X;Y
• Summary: This gene encodes a GTP binding protein and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. [provided by RefSeq, Nov 2011]

miRNA Show/Hide all (41)

miRTarBase ID	miRNA	Experiments	Reference
MIRT2007828	hsa-miR-2355-5p	CLIP-seq
MIRT2007829	hsa-miR-4313	CLIP-seq
MIRT2007830	hsa-miR-4514	CLIP-seq
MIRT2007831	hsa-miR-4645-5p	CLIP-seq
MIRT2007832	hsa-miR-4673	CLIP-seq
MIRT2007833	hsa-miR-4692	CLIP-seq
MIRT2007834	hsa-miR-614	CLIP-seq
MIRT2007835	hsa-miR-885-3p	CLIP-seq
MIRT2007828	hsa-miR-2355-5p	CLIP-seq
MIRT2240486	hsa-miR-3130-3p	CLIP-seq
MIRT2240487	hsa-miR-3173-3p	CLIP-seq
MIRT2240488	hsa-miR-3622a-3p	CLIP-seq
MIRT2240489	hsa-miR-3622b-3p	CLIP-seq
MIRT2240490	hsa-miR-370	CLIP-seq
MIRT2007830	hsa-miR-4514	CLIP-seq
MIRT2007831	hsa-miR-4645-5p	CLIP-seq
MIRT2007832	hsa-miR-4673	CLIP-seq
MIRT2007833	hsa-miR-4692	CLIP-seq
MIRT2240491	hsa-miR-4725-5p	CLIP-seq
MIRT2240492	hsa-miR-4751	CLIP-seq
MIRT2240493	hsa-miR-504	CLIP-seq
MIRT2007834	hsa-miR-614	CLIP-seq
MIRT2007835	hsa-miR-885-3p	CLIP-seq
MIRT2388857	hsa-miR-147	CLIP-seq
MIRT2388858	hsa-miR-214	CLIP-seq
MIRT2388859	hsa-miR-219-2-3p	CLIP-seq
MIRT2388860	hsa-miR-27a	CLIP-seq
MIRT2388861	hsa-miR-27b	CLIP-seq
MIRT2388862	hsa-miR-3153	CLIP-seq
MIRT2388863	hsa-miR-3155	CLIP-seq
MIRT2388864	hsa-miR-3155b	CLIP-seq
MIRT2388865	hsa-miR-3619-5p	CLIP-seq
MIRT2388866	hsa-miR-3691-5p	CLIP-seq
MIRT2388867	hsa-miR-3911	CLIP-seq
MIRT2388868	hsa-miR-4269	CLIP-seq
MIRT2388869	hsa-miR-4690-5p	CLIP-seq
MIRT2388870	hsa-miR-4752	CLIP-seq
MIRT2388871	hsa-miR-484	CLIP-seq
MIRT2388872	hsa-miR-513a-5p	CLIP-seq
MIRT2388873	hsa-miR-644	CLIP-seq
MIRT2388874	hsa-miR-761	CLIP-seq

Gene ontology (GO) Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0005525	Function	GTP binding	IEA
GO:0005525	Function	GTP binding	TAS	9466997
GO:0005737	Component	Cytoplasm	IBA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0043022	Function	Ribosome binding	IBA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 300124
• HGNC: 30189
• e!Ensembl: ENSG00000178605

Protein

• UniProt ID: O43824
• Protein name: Putative GTP-binding protein 6 (Pseudoautosomal GTP-binding protein-like)
• PDB: 7OF2 , 7OF4 , 7OF6
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01926	MMR_HSR1	296 → 419	50S ribosome-binding GTPase	Family
  PF13167	GTP-bdg_N	118 → 209	GTP-binding GTPase N-terminal	Family
  PF16360	GTP-bdg_M	211 → 289	GTP-binding GTPase Middle Region	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:9466997}.
• Sequence:

  MWALRAAVRPGLRLSRVGRGRSAPRAAAPSCPARALAAVGRRSPGNLEGPWGGGRGLRAD
  GGRSRTGDDEEEPEDADENAEEELLRGEPLLPAGTQRVCLVHPDVKWGPGKSQMTRAEWQ
  VAEATALVHTLDGWSVVQTMVVSTKTPDRKLIFGKGNFEHLTEKIRGSPDITCVFLNVER
  MAAPTKKELEAAWGVEVFDRFTVVLHIFRCNARTKEARLQVALAEMPLHRSNLKRDVAHL
  YRGVGSRYIMGSGESFMQLQQRLLREKEAKIRKALDRLRKKRHLLRRQRTRREFPVISVV
  GYTNCGKTTLIKALTGDAAIQPRDQLFATLDVTAHAGTLPSRMTVLYVDTIGFLSQLPHG
  LIESFSATLEDVAHSDLILHVRDVSHPEAELQKCSVLSTLRGLQLPAPLLDSMVEVHNKV
  DLVPGYSPTEPNVVPVSALRGHGLQELKAELDAAVLKATGRQILTLRVRLAGAQLSWLYK
  EATVQEVDVIPEDGAADVRVIISNSAYGKFRKLFPG

• Sequence length: 516

Related Genes

No strongly related genes found yet for GTPBP6.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to GTPBP6.