Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	80273
Gene name	GrpE like 1, mitochondrial
Gene symbol	GRPEL1
Synonyms (NCBI Gene)	GrpEHMGEmt-GrpE#1
Chromosome	4
Chromosome location	4p16.1

105 Show/Hide all (105)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020623	hsa-miR-155-5p	Proteomics	18668040
MIRT027433	hsa-miR-98-5p	Microarray	19088304
MIRT042368	hsa-miR-484	CLASH	23622248
MIRT039522	hsa-miR-652-3p	CLASH	23622248
MIRT1035302	hsa-miR-1202	CLIP-seq
MIRT1035303	hsa-miR-1267	CLIP-seq
MIRT1035304	hsa-miR-1305	CLIP-seq
MIRT1035305	hsa-miR-1343	CLIP-seq
MIRT1035306	hsa-miR-1910	CLIP-seq
MIRT1035307	hsa-miR-205	CLIP-seq
MIRT1035308	hsa-miR-2116	CLIP-seq
MIRT1035309	hsa-miR-223	CLIP-seq
MIRT1035310	hsa-miR-3122	CLIP-seq
MIRT1035311	hsa-miR-3124-3p	CLIP-seq
MIRT1035312	hsa-miR-3136-5p	CLIP-seq
MIRT1035313	hsa-miR-3153	CLIP-seq
MIRT1035314	hsa-miR-323b-3p	CLIP-seq
MIRT1035315	hsa-miR-3545-5p	CLIP-seq
MIRT1035316	hsa-miR-3680	CLIP-seq
MIRT1035317	hsa-miR-3913-5p	CLIP-seq
MIRT1035318	hsa-miR-3972	CLIP-seq
MIRT1035319	hsa-miR-412	CLIP-seq
MIRT1035320	hsa-miR-4264	CLIP-seq
MIRT1035321	hsa-miR-4328	CLIP-seq
MIRT1035322	hsa-miR-4439	CLIP-seq
MIRT1035323	hsa-miR-4464	CLIP-seq
MIRT1035324	hsa-miR-4480	CLIP-seq
MIRT1035325	hsa-miR-4513	CLIP-seq
MIRT1035326	hsa-miR-4668-5p	CLIP-seq
MIRT1035327	hsa-miR-4677-5p	CLIP-seq
MIRT1035328	hsa-miR-4719	CLIP-seq
MIRT1035329	hsa-miR-4748	CLIP-seq
MIRT1035330	hsa-miR-4755-3p	CLIP-seq
MIRT1035331	hsa-miR-4760-5p	CLIP-seq
MIRT1035332	hsa-miR-4773	CLIP-seq
MIRT1035333	hsa-miR-4776-3p	CLIP-seq
MIRT1035334	hsa-miR-4797-3p	CLIP-seq
MIRT1035335	hsa-miR-513b	CLIP-seq
MIRT1035336	hsa-miR-539	CLIP-seq
MIRT1035337	hsa-miR-580	CLIP-seq
MIRT1035338	hsa-miR-660	CLIP-seq
MIRT1035339	hsa-miR-802	CLIP-seq
MIRT1035340	hsa-miR-943	CLIP-seq
MIRT1035302	hsa-miR-1202	CLIP-seq
MIRT1035306	hsa-miR-1910	CLIP-seq
MIRT2006952	hsa-miR-203	CLIP-seq
MIRT1035307	hsa-miR-205	CLIP-seq
MIRT1035314	hsa-miR-323b-3p	CLIP-seq
MIRT1035318	hsa-miR-3972	CLIP-seq
MIRT2006953	hsa-miR-4501	CLIP-seq
MIRT1035330	hsa-miR-4755-3p	CLIP-seq
MIRT1035333	hsa-miR-4776-3p	CLIP-seq
MIRT1035336	hsa-miR-539	CLIP-seq
MIRT1035337	hsa-miR-580	CLIP-seq
MIRT1035339	hsa-miR-802	CLIP-seq
MIRT1035302	hsa-miR-1202	CLIP-seq
MIRT2239480	hsa-miR-155	CLIP-seq
MIRT2239481	hsa-miR-3119	CLIP-seq
MIRT1035310	hsa-miR-3122	CLIP-seq
MIRT2239482	hsa-miR-3147	CLIP-seq
MIRT1035314	hsa-miR-323b-3p	CLIP-seq
MIRT1035317	hsa-miR-3913-5p	CLIP-seq
MIRT1035318	hsa-miR-3972	CLIP-seq
MIRT2239483	hsa-miR-409-5p	CLIP-seq
MIRT2239484	hsa-miR-4259	CLIP-seq
MIRT1035323	hsa-miR-4464	CLIP-seq
MIRT2239485	hsa-miR-4517	CLIP-seq
MIRT2239486	hsa-miR-4652-3p	CLIP-seq
MIRT1035329	hsa-miR-4748	CLIP-seq
MIRT1035330	hsa-miR-4755-3p	CLIP-seq
MIRT1035333	hsa-miR-4776-3p	CLIP-seq
MIRT2239487	hsa-miR-548a-5p	CLIP-seq
MIRT2239488	hsa-miR-548ab	CLIP-seq
MIRT2239489	hsa-miR-548ak	CLIP-seq
MIRT2239490	hsa-miR-548b-5p	CLIP-seq
MIRT2239491	hsa-miR-548c-5p	CLIP-seq
MIRT2239492	hsa-miR-548d-5p	CLIP-seq
MIRT2239493	hsa-miR-548h	CLIP-seq
MIRT2239494	hsa-miR-548i	CLIP-seq
MIRT2239495	hsa-miR-548j	CLIP-seq
MIRT2239496	hsa-miR-548k	CLIP-seq
MIRT2239497	hsa-miR-548l	CLIP-seq
MIRT2239498	hsa-miR-548w	CLIP-seq
MIRT2239499	hsa-miR-548y	CLIP-seq
MIRT2239500	hsa-miR-559	CLIP-seq
MIRT1035339	hsa-miR-802	CLIP-seq
MIRT2239480	hsa-miR-155	CLIP-seq
MIRT2239481	hsa-miR-3119	CLIP-seq
MIRT2239482	hsa-miR-3147	CLIP-seq
MIRT2239484	hsa-miR-4259	CLIP-seq
MIRT2239486	hsa-miR-4652-3p	CLIP-seq
MIRT2543216	hsa-miR-4662a-5p	CLIP-seq
MIRT2239480	hsa-miR-155	CLIP-seq
MIRT2239481	hsa-miR-3119	CLIP-seq
MIRT1035310	hsa-miR-3122	CLIP-seq
MIRT2239482	hsa-miR-3147	CLIP-seq
MIRT1035314	hsa-miR-323b-3p	CLIP-seq
MIRT1035317	hsa-miR-3913-5p	CLIP-seq
MIRT2239483	hsa-miR-409-5p	CLIP-seq
MIRT2682097	hsa-miR-4252	CLIP-seq
MIRT2239484	hsa-miR-4259	CLIP-seq
MIRT1035323	hsa-miR-4464	CLIP-seq
MIRT2239486	hsa-miR-4652-3p	CLIP-seq
MIRT2543216	hsa-miR-4662a-5p	CLIP-seq
MIRT1035329	hsa-miR-4748	CLIP-seq

21 Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000774	Function	Adenyl-nucleotide exchange factor activity	IBA
GO:0000774	Function	Adenyl-nucleotide exchange factor activity	IEA
GO:0001405	Component	PAM complex, Tim23 associated import motor	IBA
GO:0005515	Function	Protein binding	IPI	28514442, 30021884, 32296183, 33961781
GO:0005654	Component	Nucleoplasm	IDA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	10339406
GO:0005744	Component	TIM23 mitochondrial import inner membrane translocase complex	NAS	10339406
GO:0005759	Component	Mitochondrial matrix	IDA	11311562
GO:0005759	Component	Mitochondrial matrix	IEA
GO:0006457	Process	Protein folding	IEA
GO:0006886	Process	Intracellular protein transport	NAS	10339406
GO:0030150	Process	Protein import into mitochondrial matrix	IBA
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	32296183
GO:0042803	Function	Protein homodimerization activity	IEA
GO:0051082	Function	Unfolded protein binding	IBA
GO:0051082	Function	Unfolded protein binding	IDA	11311562
GO:0051087	Function	Protein-folding chaperone binding	IEA

MIM	HGNC	e!Ensembl
606173	19696	ENSG00000109519

Q9HAV7

Protein name

GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1)

Protein function

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleo

PDB

9BLS , 9BLT , 9BLU

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01025	GrpE	32 → 215	GrpE	Family

Sequence

MAAQCVRLARRSLPALALSLRPSPRLLCTATKQKNSGQNLEEDMGQSEQKADPPATEKTL
LEEKVKLEEQLKETVEKYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLEVADVLEK
ATQCVPKEEIKDDNPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNPVGAKFDPYEHEALFH
TPVEGKEPGTVALVSKVGYKLHGRTLRPALVGVVKEA

Sequence length

217

Interactions

View interactions

Related Genes Genes most often co-reported with GRPEL1 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for GRPEL1.

Diseases Linked via Similar Genes Diseases curated for genes most similar to GRPEL1 (see Related Genes above), that are NOT already directly curated for GRPEL1 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to GRPEL1.

GRPEL1 (GrpE like 1, mitochondrial)

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