GRAMD1C (GRAM domain containing 1C)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 54762
• Gene name: GRAM domain containing 1C
• Gene symbol: GRAMD1C
• Synonyms (NCBI Gene): -
• Chromosome: 3
• Chromosome location: 3q13.31

miRNA Show/Hide all (115)

miRTarBase ID	miRNA	Experiments	Reference
MIRT446265	hsa-miR-548a-3p	PAR-CLIP	22100165
MIRT446264	hsa-miR-548ar-3p	PAR-CLIP	22100165
MIRT446263	hsa-miR-548az-3p	PAR-CLIP	22100165
MIRT446262	hsa-miR-548e-3p	PAR-CLIP	22100165
MIRT446261	hsa-miR-548f-3p	PAR-CLIP	22100165
MIRT446259	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT446260	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT446257	hsa-miR-4682	PAR-CLIP	22100165
MIRT446258	hsa-miR-4424	PAR-CLIP	22100165
MIRT446265	hsa-miR-548a-3p	PAR-CLIP	22100165
MIRT446264	hsa-miR-548ar-3p	PAR-CLIP	22100165
MIRT446263	hsa-miR-548az-3p	PAR-CLIP	22100165
MIRT446262	hsa-miR-548e-3p	PAR-CLIP	22100165
MIRT446261	hsa-miR-548f-3p	PAR-CLIP	22100165
MIRT446259	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT446260	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT446257	hsa-miR-4682	PAR-CLIP	22100165
MIRT446258	hsa-miR-4424	PAR-CLIP	22100165
MIRT446265	hsa-miR-548a-3p	PAR-CLIP	22100165
MIRT446264	hsa-miR-548ar-3p	PAR-CLIP	22100165
MIRT446263	hsa-miR-548az-3p	PAR-CLIP	22100165
MIRT446262	hsa-miR-548e-3p	PAR-CLIP	22100165
MIRT446261	hsa-miR-548f-3p	PAR-CLIP	22100165
MIRT446259	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT446260	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT446257	hsa-miR-4682	PAR-CLIP	22100165
MIRT446258	hsa-miR-4424	PAR-CLIP	22100165
MIRT446265	hsa-miR-548a-3p	PAR-CLIP	22100165
MIRT446264	hsa-miR-548ar-3p	PAR-CLIP	22100165
MIRT446263	hsa-miR-548az-3p	PAR-CLIP	22100165
MIRT446262	hsa-miR-548e-3p	PAR-CLIP	22100165
MIRT446261	hsa-miR-548f-3p	PAR-CLIP	22100165
MIRT446259	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT446260	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT446257	hsa-miR-4682	PAR-CLIP	22100165
MIRT446258	hsa-miR-4424	PAR-CLIP	22100165
MIRT1032762	hsa-miR-1236	CLIP-seq
MIRT1032763	hsa-miR-190	CLIP-seq
MIRT1032764	hsa-miR-190b	CLIP-seq
MIRT1032765	hsa-miR-2355-5p	CLIP-seq
MIRT1032766	hsa-miR-297	CLIP-seq
MIRT1032767	hsa-miR-31	CLIP-seq
MIRT1032768	hsa-miR-3134	CLIP-seq
MIRT1032769	hsa-miR-3149	CLIP-seq
MIRT1032770	hsa-miR-3150b-3p	CLIP-seq
MIRT1032771	hsa-miR-3201	CLIP-seq
MIRT1032772	hsa-miR-3612	CLIP-seq
MIRT1032773	hsa-miR-3616-5p	CLIP-seq
MIRT1032774	hsa-miR-3647-5p	CLIP-seq
MIRT1032775	hsa-miR-3679-3p	CLIP-seq
MIRT1032776	hsa-miR-3682-5p	CLIP-seq
MIRT1032777	hsa-miR-3919	CLIP-seq
MIRT1032778	hsa-miR-3924	CLIP-seq
MIRT1032779	hsa-miR-4446-5p	CLIP-seq
MIRT1032780	hsa-miR-4635	CLIP-seq
MIRT1032781	hsa-miR-4689	CLIP-seq
MIRT1032782	hsa-miR-4695-5p	CLIP-seq
MIRT1032783	hsa-miR-4784	CLIP-seq
MIRT1032784	hsa-miR-4789-3p	CLIP-seq
MIRT1032785	hsa-miR-4791	CLIP-seq
MIRT1032786	hsa-miR-4802-5p	CLIP-seq
MIRT1032787	hsa-miR-502-5p	CLIP-seq
MIRT1032788	hsa-miR-573	CLIP-seq
MIRT1032789	hsa-miR-642b	CLIP-seq
MIRT1032790	hsa-miR-643	CLIP-seq
MIRT1032791	hsa-miR-650	CLIP-seq
MIRT1032792	hsa-miR-101	CLIP-seq
MIRT1032762	hsa-miR-1236	CLIP-seq
MIRT1032793	hsa-miR-1298	CLIP-seq
MIRT1032794	hsa-miR-1323	CLIP-seq
MIRT1032795	hsa-miR-144	CLIP-seq
MIRT1032796	hsa-miR-2110	CLIP-seq
MIRT1032766	hsa-miR-297	CLIP-seq
MIRT1032797	hsa-miR-3119	CLIP-seq
MIRT1032798	hsa-miR-3144-5p	CLIP-seq
MIRT1032769	hsa-miR-3149	CLIP-seq
MIRT1032799	hsa-miR-3150a-3p	CLIP-seq
MIRT1032800	hsa-miR-3191	CLIP-seq
MIRT1032773	hsa-miR-3616-5p	CLIP-seq
MIRT1032774	hsa-miR-3647-5p	CLIP-seq
MIRT1032801	hsa-miR-3662	CLIP-seq
MIRT1032776	hsa-miR-3682-5p	CLIP-seq
MIRT1032802	hsa-miR-4260	CLIP-seq
MIRT1032803	hsa-miR-4434	CLIP-seq
MIRT1032804	hsa-miR-4516	CLIP-seq
MIRT1032805	hsa-miR-4522	CLIP-seq
MIRT1032806	hsa-miR-4531	CLIP-seq
MIRT1032780	hsa-miR-4635	CLIP-seq
MIRT1032807	hsa-miR-4652-5p	CLIP-seq
MIRT1032808	hsa-miR-4684-5p	CLIP-seq
MIRT1032809	hsa-miR-4731-3p	CLIP-seq
MIRT1032784	hsa-miR-4789-3p	CLIP-seq
MIRT1032810	hsa-miR-4801	CLIP-seq
MIRT1032786	hsa-miR-4802-5p	CLIP-seq
MIRT1032811	hsa-miR-490-3p	CLIP-seq
MIRT1032787	hsa-miR-502-5p	CLIP-seq
MIRT1032812	hsa-miR-516b	CLIP-seq
MIRT1032813	hsa-miR-548o	CLIP-seq
MIRT1032788	hsa-miR-573	CLIP-seq
MIRT1032814	hsa-miR-582-5p	CLIP-seq
MIRT1032815	hsa-miR-619	CLIP-seq
MIRT1032789	hsa-miR-642b	CLIP-seq
MIRT1032790	hsa-miR-643	CLIP-seq
MIRT2006365	hsa-miR-3143	CLIP-seq
MIRT2006366	hsa-miR-365	CLIP-seq
MIRT2006367	hsa-miR-4803	CLIP-seq
MIRT2238827	hsa-miR-3185	CLIP-seq
MIRT1032801	hsa-miR-3662	CLIP-seq
MIRT2238828	hsa-miR-4420	CLIP-seq
MIRT2238829	hsa-miR-4786-3p	CLIP-seq
MIRT1032786	hsa-miR-4802-5p	CLIP-seq
MIRT2238830	hsa-miR-520d-5p	CLIP-seq
MIRT2238831	hsa-miR-524-5p	CLIP-seq
MIRT2238832	hsa-miR-586	CLIP-seq
MIRT2238833	hsa-miR-668	CLIP-seq

Gene ontology (GO) Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 25910212, 29892012, 32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	ISS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0006869	Process	Lipid transport	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0015485	Function	Cholesterol binding	IBA
GO:0015485	Function	Cholesterol binding	IEA
GO:0015485	Function	Cholesterol binding	ISS
GO:0016020	Component	Membrane	IEA
GO:0032366	Process	Intracellular sterol transport	IBA
GO:0044232	Component	Organelle membrane contact site	IEA
GO:0071397	Process	Cellular response to cholesterol	IEA
GO:0071397	Process	Cellular response to cholesterol	ISS
GO:0120020	Function	Cholesterol transfer activity	IBA
GO:0120020	Function	Cholesterol transfer activity	IEA
GO:0120020	Function	Cholesterol transfer activity	ISS
GO:0140268	Component	Endoplasmic reticulum-plasma membrane contact site	IBA
GO:0140268	Component	Endoplasmic reticulum-plasma membrane contact site	IEA
GO:0140268	Component	Endoplasmic reticulum-plasma membrane contact site	ISS

Other IDs

• MIM: 620180
• HGNC: 25252
• e!Ensembl: ENSG00000178075

Protein

• UniProt ID: Q8IYS0
• Protein name: Protein Aster-C (GRAM domain-containing protein 1C)
• Protein function: Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecu
• PDB: 6GN5
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02893	GRAM	69 → 178	GRAM domain	Domain
  PF16016	VASt	329 → 477	VAD1 Analog of StAR-related lipid transfer domain	Domain

• Sequence:

  MEGAPTVRQVMNEGDSSLATDLQEDVEENPSPTVEENNVVVKKQGPNLHNWSGDWSFWIS
  SSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWET
  TISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDK
  SLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRSPGRSSLDDSGERDEKLSKSI
  SFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPSKSLDLNK
  NEYLSLDKSSTSDSVDEENVPEKDLHGRLFINRIFHISADRMFELLFTSSRFMQKFASSR
  NIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTAATEKQTLYKESREARFYLVDSE
  VLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKSLIEKNSWSSLED
  YFKQLESDLLIEESVLNQAIEDPGKLTGLRRRRRTFNRTAETVPKLSSQHSSGDVGLGAK
  GDITGKKKEMENYNVTLIVVMSIFVLLLVLLNVTLFLKLSKIEHAAQSFYRLRLQEEKSL
  NLASDMVSRAETIQKNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLLNKNKTGMAV
  ES

• Sequence length: 662

Related Genes

No strongly related genes found yet for GRAMD1C.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to GRAMD1C.